Harnessing Fluorine–Sulfur Contacts and Multipolar Interactions for the Design of p53 Mutant Y220C Rescue Drugs

por Bauer, Matthias R., Jones, Rhiannon N., Baud, Matthias G. J., Wilcken, Rainer, Boeckler, Frank M., Fersht, Alan R., Joerger, Andreas C., Spencer, John
Publicado 2016

Targeting Cavity-Creating p53 Cancer Mutations with Small-Molecule Stabilizers: the Y220X Paradigm

por Bauer, Matthias R., Krämer, Andreas, Settanni, Giovanni, Jones, Rhiannon N., Ni, Xiaomin, Khan Tareque, Raysa, Fersht, Alan R., Spencer, John, Joerger, Andreas C.
Publicado 2020

A structure-guided molecular chaperone approach for restoring the transcriptional activity of the p53 cancer mutant Y220C

por Bauer, Matthias R, Jones, Rhiannon N, Tareque, Raysa K, Springett, Bradley, Dingler, Felix A, Verduci, Lorena, Patel, Ketan J, Fersht, Alan R, Joerger, Andreas C, Spencer, John
Publicado 2019

A synthetic, catalytic and theoretical investigation of an unsymmetrical SCN pincer palladacycle

por Roffe, Gavin W., Boonseng, Sarote, Baltus, Christine B., Coles, Simon J., Day, Iain J., Jones, Rhiannon N., Press, Neil J., Ruiz, Mario, Tizzard, Graham J., Cox, Hazel, Spencer, John
Publicado 2016