Regulation of drug metabolizing enzymes in the leukaemic bone marrow microenvironment

por Su, Meng, Chang, Yu‐Ting, Hernandez, Daniela, Jones, Richard J., Ghiaur, Gabriel
Publicado 2019

Sex-Related Differences in Chronic Myeloid Neoplasms: From the Clinical Observation to the Underlying Biology

por Karantanos, Theodoros, Jain, Tania, Moliterno, Alison R., Jones, Richard J., DeZern, Amy E.
Publicado 2021

HLA-matching with PTCy: a reanalysis of a CIBMTR dataset with propensity score matching and donor age

por Ambinder, Alexander, Jain, Tania, Tsai, Hua-Ling, Horowitz, Mary M., Jones, Richard J., Varadhan, Ravi
Publicado 2022

All-Trans Retinoic Acid Activity in Acute Myeloid Leukemia: Role of Cytochrome P450 Enzyme Expression by the Microenvironment

por Su, Meng, Alonso, Salvador, Jones, Jace W., Yu, Jianshi, Kane, Maureen A., Jones, Richard J., Ghiaur, Gabriel
Publicado 2015

Human bone marrow niche chemoprotection mediated by cytochrome p450 enzymes

por Alonso, Salvador, Su, Meng, Jones, Jace W., Ganguly, Sudipto, Kane, Maureen A., Jones, Richard J., Ghiaur, Gabriel
Publicado 2015

Nonmyeloablative, HLA-haploidentical bone marrow transplantation with high dose, post-transplantation cyclophosphamide

por Munchel, Ashley, Kesserwan, Chimen, Symons, Heather J., Luznik, Leo, Kasamon, Yvette L., Jones, Richard J., Fuchs, Ephraim J.
Publicado 2011

Chondroitin sulfate proteoglycan serglycin influences protein cargo loading and functions of tumor-derived exosomes

por Purushothaman, Anurag, Bandari, Shyam K., Chandrashekar, Darshan S., Jones, Richard J., Lee, Hans C., Weber, Donna M., Orlowski, Robert Z.
Publicado 2017

Telomerase Inhibition Targets Clonogenic Multiple Myeloma Cells through Telomere Length-Dependent and Independent Mechanisms

por Brennan, Sarah K., Wang, Qiuju, Tressler, Robert, Harley, Calvin, Go, Ning, Bassett, Ekaterina, Huff, Carol Ann, Jones, Richard J., Matsui, William
Publicado 2010

Epstein-Barr virus-specific methylation of human genes in gastric cancer cells

por Ryan, Julie L, Jones, Richard J, Kenney, Shannon C, Rivenbark, Ashley G, Tang, Weihua, Knight, Elizabeth RW, Coleman, William B, Gulley, Margaret L
Publicado 2010

Genome-wide comparison of the transcriptomes of highly enriched normal and chronic myeloid leukemia stem and progenitor cell populations

por Gerber, Jonathan M., Gucwa, Jessica L., Esopi, David, Gurel, Meltem, Haffner, Michael C., Vala, Milada, Nelson, William G., Jones, Richard J., Yegnasubramanian, Srinivasan
Publicado 2013

Reduced Intensity Bone Marrow Transplantation with Post-Transplant Cyclophosphamide for Pediatric Inherited Immune Deficiencies and Bone Marrow Failure Syndromes

por Klein, Orly R., Bapty, Samantha, Lederman, Howard M., Younger, M. Elizabeth M., Zambidis, Elias T., Jones, Richard J., Cooke, Kenneth R., Symons, Heather J.
Publicado 2020

Identification and characterization of a spontaneous ovarian carcinoma in Lewis rats

por Sharrow, Allison C, Ronnett, Brigitte M, Thoburn, Christopher J, Barber, James P, Giuntoli, Robert L, Armstrong, Deborah K, Jones, Richard J, Hess, Allan D
Publicado 2010

Inhibition of the MDM2 E3 Ligase Induces Apoptosis and Autophagy in Wild-Type and Mutant p53 Models of Multiple Myeloma, and Acts Synergistically with ABT-737

por Gu, Dongmin, Wang, Shuhong, Kuiatse, Isere, Wang, Hua, He, Jin, Dai, Yun, Jones, Richard J., Bjorklund, Chad C., Yang, Jing, Grant, Steven, Orlowski, Robert Z.
Publicado 2014

Identification of Novel p53 Pathway Activating Small-Molecule Compounds Reveals Unexpected Similarities with Known Therapeutic Agents

por Peltonen, Karita, Colis, Laureen, Liu, Hester, Jäämaa, Sari, Moore, Henna M., Enbäck, Juulia, Laakkonen, Pirjo, Vaahtokari, Anne, Jones, Richard J., af Hällström, Taija M., Laiho, Marikki
Publicado 2010

Intravenous Immunoglobulin G Suppresses Heat Shock Protein (HSP)-70 Expression and Enhances the Activity of HSP90 and Proteasome Inhibitors

por Jones, Richard J., Singh, Ram K., Shirazi, Fazal, Wan, Jie, Wang, Hua, Wang, Xiaobin, Ha, Min Jin, Baljevic, Muhamed, Kuiatse, Isere, Davis, Richard E., Orlowski, Robert Z.
Publicado 2020

A Phase 1 Study of IRX195183, a RARα-Selective CYP26 Resistant Retinoid, in Patients With Relapsed or Refractory AML

por Ambinder, Alexander J., Norsworthy, Kelly, Hernandez, Daniela, Palau, Laura, Paun, Bogdan, Duffield, Amy, Chandraratna, Rosh, Sanders, Martin, Varadhan, Ravi, Jones, Richard J., Douglas Smith, B., Ghiaur, Gabriel
Publicado 2020

Hematopoietic Cell Transplantation: Practice Predictions for the Year 2023

por Farhadfar, Nosha, Burns, Linda J., Mupfudze, Tatenda, Shaw, Bronwen E., Bollard, Catherine M., Devine, Steven M., Horowitz, Mary M., Jones, Richard J., Murthy, Hemant S., Wingard, John R., Lee, Stephanie J.
Publicado 2021

Cell-free DNA measurable residual disease as a predictor of postallogeneic hematopoietic cell transplant outcomes

por Pasca, Sergiu, Guo, Matthew Z., Wang, Shiyu, Stokvis, Kristin, Shedeck, Audra, Pallavajjala, Aparna, Shams, Cynthia, Pallavajjala, Roshni, DeZern, Amy E., Varadhan, Ravi, Gocke, Christopher D., Jones, Richard J., Gondek, Lukasz P.
Publicado 2023

The role of the atypical chemokine receptor CCRL2 in myelodysplastic syndrome and secondary acute myeloid leukemia

por Karantanos, Theodoros, Teodorescu, Patric, Perkins, Brandy, Christodoulou, Ilias, Esteb, Christopher, Varadhan, Ravi, Helmenstine, Eric, Rajkhowa, Trivikram, Paun, Bogdan C., Bonifant, Challice, Dalton, W. Brian, Gondek, Lukasz P., Moliterno, Alison R., Levis, Mark J., Ghiaur, Gabriel, Jones, Richard J.
Publicado 2022

CCRL2 affects the sensitivity of myelodysplastic syndrome and secondary acute myeloid leukemia cells to azacitidine

por Karantanos, Theodoros, Teodorescu, Patric, Arvanitis, Marios, Perkins, Brandy, Jain, Tania, DeZern, Amy E., Dalton, W. Brian, Christodoulou, Ilias, Paun, Bogdan C., Varadhan, Ravi, Esteb, Christopher, Rajkhowa, Trivikram, Bonifant, Challice, Gondek, Lukasz P., Levis, Mark J., Yegnasubramanian, Srinivasan, Ghiaur, Gabriel, Jones, Richard J.
Publicado 2022