Context-specific effects of genetic variants associated with autoimmune disease

por Jonkers, Iris H., Wijmenga, Cisca
Publicado 2017

Genome-wide dynamics of Pol II elongation and its interplay with promoter proximal pausing, chromatin, and exons

por Jonkers, Iris, Kwak, Hojoong, Lis, John T
Publicado 2014

Molecular Biomarkers for Celiac Disease: Past, Present and Future

por Ramírez-Sánchez, Aarón D., Tan, Ineke L., Gonera-de Jong, B.C., Visschedijk, Marijn C., Jonkers, Iris, Withoff, Sebo
Publicado 2020

A Combined mRNA- and miRNA-Sequencing Approach Reveals miRNAs as Potential Regulators of the Small Intestinal Transcriptome in Celiac Disease

por Tan, Ineke Luise, Barisani, Donatella, Panceri, Roberto, Modderman, Rutger, Visschedijk, Marijn, Weersma, Rinse K., Wijmenga, Cisca, Jonkers, Iris, Coutinho de Almeida, Rodrigo, Withoff, Sebo
Publicado 2021

The Probability to Initiate X Chromosome Inactivation Is Determined by the X to Autosomal Ratio and X Chromosome Specific Allelic Properties

por Monkhorst, Kim, de Hoon, Bas, Jonkers, Iris, Mulugeta Achame, Eskeatnaf, Monkhorst, Wouter, Hoogerbrugge, Jos, Rentmeester, Eveline, Westerhoff, Hans V., Grosveld, Frank, Grootegoed, J. Anton, Gribnau, Joost
Publicado 2009

Tissue alarmins and adaptive cytokine induce dynamic and distinct transcriptional responses in tissue-resident intraepithelial cytotoxic T lymphocytes

por Zorro, Maria Magdalena, Aguirre-Gamboa, Raul, Mayassi, Toufic, Ciszewski, Cezary, Barisani, Donatella, Hu, Shixian, Weersma, Rinse K, Withoff, Sebo, Li, Yang, Wijmenga, Cisca, Jabri, Bana, Jonkers, Iris H
Publicado 2020

Kinetics of Xist-induced gene silencing can be predicted from combinations of epigenetic and genomic features

por Barros de Andrade e Sousa, Lisa, Jonkers, Iris, Syx, Laurène, Dunkel, Ilona, Chaumeil, Julie, Picard, Christel, Foret, Benjamin, Chen, Chong-Jian, Lis, John T., Heard, Edith, Schulz, Edda G., Marsico, Annalisa
Publicado 2019

Single-Cell RNA Sequencing of Peripheral Blood Mononuclear Cells From Pediatric Coeliac Disease Patients Suggests Potential Pre-Seroconversion Markers

por Ramírez-Sánchez, Aarón D., Chu, Xiaojing, Modderman, Rutger, Kooy-Winkelaar, Yvonne, Koletzko, Sibylle, Korponay-Szabó, Ilma R., Troncone, Riccardo, Wijmenga, Cisca, Mearin, Luisa, Withoff, Sebo, Jonkers, Iris H., Li, Yang
Publicado 2022

CTCF regulates the local epigenetic state of ribosomal DNA repeats

por van de Nobelen, Suzanne, Rosa-Garrido, Manuel, Leers, Joerg, Heath, Helen, Soochit, Widia, Joosen, Linda, Jonkers, Iris, Demmers, Jeroen, van der Reijden, Michael, Torrano, Verónica, Grosveld, Frank, Delgado, M Dolores, Renkawitz, Rainer, Galjart, Niels, Sleutels, Frank
Publicado 2010

Gut mucosa dissociation protocols influence cell type proportions and single-cell gene expression levels

por Uniken Venema, Werna T. C., Ramírez-Sánchez, Aarón D., Bigaeva, Emilia, Withoff, Sebo, Jonkers, Iris, McIntyre, Rebecca E., Ghouraba, Mennatallah, Raine, Tim, Weersma, Rinse K., Franke, Lude, Festen, Eleonora A. M., van der Wijst, Monique G. P.
Publicado 2022

Using Existing Clinical Information Models for Dutch Quality Registries to Reuse Data and Follow COUMT Paradigm

por Schepens, Maike H. J., Trompert, Annemarie C., van Hooff, Miranda L., van der Velde, Erik, Kallewaard, Marjon, Verberk-Jonkers, Iris J. A. M., Cense, Huib A., Somford, Diederik M., Repping, Sjoerd, Tromp, Selma C., Wouters, Michel W. J. M.
Publicado 2023

Inflammatory Protein Profiles in Plasma of Candidaemia Patients and the Contribution of Host Genetics to Their Variability

por Matzaraki, Vasiliki, Le, Kieu T. T., Jaeger, Martin, Aguirre-Gamboa, Raúl, Johnson, Melissa D., Sanna, Serena, Rosati, Diletta, Franke, Lude, Zhernakova, Alexandra, Fu, Jingyuan, Withoff, Sebo, Jonkers, Iris, Li, Yang, Joosten, Leo A. B., Netea, Mihai G., Wijmenga, Cisca, Kumar, Vinod
Publicado 2021

An integrative genomics approach identifies novel pathways that influence candidaemia susceptibility

por Matzaraki, Vasiliki, Gresnigt, Mark S., Jaeger, Martin, Ricaño-Ponce, Isis, Johnson, Melissa D., Oosting, Marije, Franke, Lude, Withoff, Sebo, Perfect, John R., Joosten, Leo A. B., Kullberg, Bart Jan, van de Veerdonk, Frank L., Jonkers, Iris, Li, Yang, Wijmenga, Cisca, Netea, Mihai G., Kumar, Vinod
Publicado 2017

Systematic Prioritization of Candidate Genes in Disease Loci Identifies TRAFD1 as a Master Regulator of IFNγ Signaling in Celiac Disease

por van der Graaf, Adriaan, Zorro, Maria M., Claringbould, Annique, Võsa, Urmo, Aguirre-Gamboa, Raúl, Li, Chan, Mooiweer, Joram, Ricaño-Ponce, Isis, Borek, Zuzanna, Koning, Frits, Kooy-Winkelaar, Yvonne, Sollid, Ludvig M., Qiao, Shuo-Wang, Kumar, Vinod, Li, Yang, Franke, Lude, Withoff, Sebo, Wijmenga, Cisca, Sanna, Serena, Jonkers, Iris
Publicado 2021

Potential impact of celiac disease genetic risk factors on T cell receptor signaling in gluten-specific CD4+ T cells

por Bakker, Olivier B., Ramírez-Sánchez, Aarón D., Borek, Zuzanna A., de Klein, Niek, Li, Yang, Modderman, Rutger, Kooy-Winkelaar, Yvonne, Johannesen, Marie K., Matarese, Filomena, Martens, Joost H. A., Kumar, Vinod, van Bergen, Jeroen, Qiao, Shuo-Wang, Lundin, Knut E. A., Sollid, Ludvig M., Koning, Frits, Wijmenga, Cisca, Withoff, Sebo, Jonkers, Iris H.
Publicado 2021

Refined mapping of autoimmune disease associated genetic variants with gene expression suggests an important role for non-coding RNAs

por Ricaño-Ponce, Isis, Zhernakova, Daria V., Deelen, Patrick, Luo, Oscar, Li, Xingwang, Isaacs, Aaron, Karjalainen, Juha, Di Tommaso, Jennifer, Borek, Zuzanna Agnieszka, Zorro, Maria M., Gutierrez-Achury, Javier, Uitterlinden, Andre G., Hofman, Albert, van Meurs, Joyce, Netea, Mihai G., Jonkers, Iris H., Withoff, Sebo, van Duijn, Cornelia M., Li, Yang, Ruan, Yijun, Franke, Lude, Wijmenga, Cisca, Kumar, Vinod
Publicado 2016

Circulating miRNAs as Potential Biomarkers for Celiac Disease Development

por Tan, Ineke L., Coutinho de Almeida, Rodrigo, Modderman, Rutger, Stachurska, Anna, Dekens, Jackie, Barisani, Donatella, Meijer, Caroline R., Roca, María, Martinez-Ojinaga, Eva, Shamir, Raanan, Auricchio, Renata, Korponay-Szabó, Ilma R., Castillejo, Gemma, Szajewska, Hania, Koletzko, Sibylle, Zhernakova, Alexandra, Kumar, Vinod, Li, Yang, Visschedijk, Marijn C., Weersma, Rinse K., Troncone, Riccardo, Mearin, M. Luisa, Wijmenga, Cisca, Jonkers, Iris, Withoff, Sebo
Publicado 2021

Antigen-driven colonic inflammation is associated with development of dysplasia in primary sclerosing cholangitis

por Shaw, Dustin G., Aguirre-Gamboa, Raúl, Vieira, Marcos C., Gona, Saideep, DiNardi, Nicholas, Wang, Anni, Dumaine, Anne, Gelderloos-Arends, Jody, Earley, Zachary M., Meckel, Katherine R., Ciszewski, Cezary, Castillo, Anabella, Monroe, Kelly, Torres, Joana, Shah, Shailja C., Colombel, Jean-Frédéric, Itzkowitz, Steven, Newberry, Rodney, Cohen, Russell D., Rubin, David T., Quince, Christopher, Cobey, Sarah, Jonkers, Iris H., Weber, Christopher R., Pekow, Joel, Wilson, Patrick C., Barreiro, Luis B., Jabri, Bana
Publicado 2023

Randomized trial of one-hour sodium bicarbonate vs standard periprocedural saline hydration in chronic kidney disease patients undergoing cardiovascular contrast procedures

por Kooiman, Judith, de Vries, Jean-Paul P. M., Van der Heyden, Jan, Sijpkens, Yvo W. J., van Dijkman, Paul R. M., Wever, Jan J., van Overhagen, Hans, Vahl, Antonie C., Aarts, Nico, Verberk-Jonkers, Iris J. A. M., Brulez, Harald F. H., Hamming, Jaap F., van der Molen, Aart J., Cannegieter, Suzanne C., Putter, Hein, van den Hout, Wilbert B., Kilicsoy, Inci, Rabelink, Ton J., Huisman, Menno V.
Publicado 2018

Deconvolution of bulk blood eQTL effects into immune cell subpopulations

por Aguirre-Gamboa, Raúl, de Klein, Niek, di Tommaso, Jennifer, Claringbould, Annique, van der Wijst, Monique GP, de Vries, Dylan, Brugge, Harm, Oelen, Roy, Võsa, Urmo, Zorro, Maria M., Chu, Xiaojin, Bakker, Olivier B., Borek, Zuzanna, Ricaño-Ponce, Isis, Deelen, Patrick, Xu, Cheng-Jiang, Swertz, Morris, Jonkers, Iris, Withoff, Sebo, Joosten, Irma, Sanna, Serena, Kumar, Vinod, Koenen, Hans J. P. M., Joosten, Leo A. B., Netea, Mihai G., Wijmenga, Cisca, Franke, Lude, Li, Yang
Publicado 2020