Neutralizing IL-17 during re-activation of experimental arthritis prevents joint inflammation and bone erosion by decreasing RANKL and IL-1

por Koenders, MI, Lubberts, E, Joosten, LAB, van den Berg, WB
Publicado 2005

IL-1-dependent cartilage damage in a macrophage-driven arthritis model can be circumvented by T cell IL-17

por Koenders, MI, Lubberts, E, Joosten, LAB, Kolls, JK, van den Berg, WB
Publicado 2004

Reporter cell lines for real-time imaging of NF-κB activation in the arthritic joint

por Smeets, RL, Joosten, LAB, van den Berg, WB, van de Loo, FAJ
Publicado 2004

Suppressor of cytokine signaling (SOCS)-3 gene transfer protects against collagen-induced arthritis

por van de Loo, FAJ, Smeets, RL, Joosten, LAB, van den Berg, WB
Publicado 2004

Expression of Toll-like receptor (TLR) 2, TLR3, TLR4 and TLR7 is increased in rheumatoid arthritis synovium and regulates cytokine production by dendritic cells upon stimulation of...

por Roelofs, MF, Joosten, LAB, Abdollahi-Roodsaz, S, van Lieshout, AWT, Radstake, TRDJ, van den Berg, WB
Publicado 2005

Interleukin-1 receptor antagonist lentiviral gene transfer to the murine knee joint ameliorates collagen-induced arthritis

por van de Loo, FAJ, Delavallee, LM, Arntz, OJ, Bennink, MB, Joosten, LAB, van den Berg, WB
Publicado 2005

Local inhibition of endogenous IL-18 through adenoviral overexpression of IL-18BPc results in reduced incidence and severity of collagen induced arthritis in mice

por Smeets, RL, van de Loo, AAJ, Joosten, LAB, Arntz, AJ, Bennink, MB, van den Berg, WB
Publicado 2002

Differential effects of IL-17 pathway in disseminated candidiasis and zymosan-induced multiple organ failure

por Veerdonk, FL van de, Kullberg, BJ, Verschueren, IC, Hendriks, T, Meer, JWM van der, Joosten, LAB, Netea, MG
Publicado 2009

Local interleukin-12 gene transfer promotes conversion of an acute to a chronic destructive murine streptococcal cell wall arthritis

por Joosten, LAB, Heuvelmans-Jacobs, M, Lubberts, E, van de Loo, FAJ, Helsen, MMA, van den Berg, WB
Publicado 2001

Toll-like receptor 4 polymorphism influences susceptibility to but not severity and outcome of rheumatoid arthritis

por Radstake, TRDJ, Franke, B, Hanssen, S, Welsing, P, Joosten, LAB, van Riel, PLCM, Barrera, P, van den Berg, WB
Publicado 2004

Local IL-17 gene therapy accelerates collagen arthritis with severe bone erosion and rank ligand and rank expression in synovial infiltrate and at bone erosion sites

por Lubberts, E, Joosten, LAB, Schwarzenberger, P, Oppers, B, van de Bersselaar, L, Kolls, JK, van den Berg, WB
Publicado 2001

inflammation-inducible intra-articular production of human IL-1 receptor antagonist results in a more efficient inhibition of collagen-induced arthritis than does constitutive expr...

por Bakker, AC, van de Loo, FAJ, Bennink, MB, Joosten, LAB, Varley, AW, Munford, RS, van den Berg, WB
Publicado 2001

IL-1-driven cartilage and bone destruction are dependent on Toll-like receptor (TLR) 4, but not TLR2

por Abdollahi-Roodsaz, S, Joosten, LAB, Roelofs, MF, Helsen, MMA, Oppers-Walgreen, B, Arndtz, CHM, Radstake, TRDJ, van den Berg, WB
Publicado 2005

IL-18 expression in synovial biopsies of patients with active rheumatoid arthritis is associated with enhanced levels of both IL-1 and TNFα

por Joosten, LAB, Barrera, P, Lubberts, E, Blom, AB, Oppers-Walgreen, B, van den Bersselaa, LAM, van den Berg, WB
Publicado 2002

Caspase-1 and ASC but not NLRP3 mediate antifungal defense in candidiasis sepsis

por Veerdonk, F van de, Joosten, LAB, Shaw, P, Smeekens, S, Meer, JWM van der, Kullberg, B-J, Netea, MG, Kanneganti, T-D
Publicado 2009

Using a tropism-modified adenoviral vector for the intra-articular production of IL-1 receptor antagonist results in a more efficient inhibition of collagen-induced arthritis than...

por Bakker, AC, van de Loo, FAJ, Arntz, OJ, Joosten, LAB, Dmitriev, I, Krasnykh, V, Curiel, DT, van den Berg, WB
Publicado 2001

Local IL-18 gene transfer prevents severe joint destruction in murine collagen-induced arthritis by induction of IL-4 and osteoprotegerin

por Joosten, LAB, Smeets, RL, Koenders, MI, Helsen, MMA, Oppers-Walgreen, B, van de Loo, FAJ, Lubberts, E, van den Berg, WB
Publicado 2005

Increased FcγRII and III expression in synovium and on monocyte derived macrophages of RA-patients results in altered function after immune complex stimulation

por Blom, AB, van Lent, PLEM, Radstake, TRDJ, Holthuysen, AEM, Slöetjes, AW, Smeets, RL, Barrera, P, Joosten, LAB, van den Berg, WB
Publicado 2002

Neutralizing synovial RANKL by local OPG gene therapy in collagen-induced arthritis prevents cartilage erosion through induction of a non-destructive type 2 synovitis

por Lubberts, E, Koenders, MI, Oppers-Walgreen, B, Wagenmans, M, van den Bersselaar, L, Joosten, LAB, Schurr, J, Kolls, JK, van den Berg, WB
Publicado 2004

Genome-wide gene expression in experimental arthritis: defining new targets of chronic/destructive rheumatoid arthritis (RA)

por Takahashi, N, Boenafaes, T, Ostendorf, B, de Hooge, ASK, Lubberts, E, van Lent, PLEM, Rottiers, P, van de Loo, FAJ, Joosten, LAB, Grooten, J, van den Berg, WB
Publicado 2002