Differential impact of 5-lipoxygenase-activating protein antagonists on the biosynthesis of leukotrienes and of specialized pro-resolving mediators

por Dahlke, Philipp, Peltner, Lukas K., Jordan, Paul M., Werz, Oliver
Publicado 2023

Substituted 1,2,4-Triazoles as Novel and Selective Inhibitors of Leukotriene Biosynthesis Targeting 5-Lipoxygenase-Activating Protein

por Olğaç, Abdurrahman, Çapan, İrfan, Dahlke, Philipp, Jordan, Paul M., Werz, Oliver, Banoglu, Erden
Publicado 2023

Synthesis of Functionalized δ‐Hydroxy‐β‐keto Esters and Evaluation of Their Anti‐inflammatory Properties

por Grosse, Michel, Günther, Kerstin, Jordan, Paul M., Roman, Dávid, Werz, Oliver, Beemelmanns, Christine
Publicado 2022

Quinazoline-4(3H)-one-7-carboxamide Derivatives as Human Soluble Epoxide Hydrolase Inhibitors with Developable 5-Lipoxygenase Activating Protein Inhibition

por Turanlı, Sümeyye, Ergül, Azize Gizem, Jordan, Paul M., Olğaç, Abdurrahman, Çalışkan, Burcu, Werz, Oliver, Banoglu, Erden
Publicado 2022

Benzoxazolone-5-Urea Derivatives as Human Soluble Epoxide Hydrolase (sEH) Inhibitors

por Gur Maz, Tugce, Koc, Beyzanur, Jordan, Paul M., İbiş, Kübra, Çalışkan, Burcu, Werz, Oliver, Banoglu, Erden
Publicado 2023

Shifting the Biosynthesis of Leukotrienes Toward Specialized Pro-Resolving Mediators by the 5-Lipoxygenase-Activating Protein (FLAP) Antagonist BRP-201

por Kretzer, Christian, Jordan, Paul M, Bilancia, Rossella, Rossi, Antonietta, Gür Maz, Tuğçe, Banoglu, Erden, Schubert, Ulrich S, Werz, Oliver
Publicado 2022

Macrophage-targeting oligopeptides from Mortierella alpina

por Wurlitzer, Jacob M., Stanišić, Aleksa, Ziethe, Sebastian, Jordan, Paul M., Günther, Kerstin, Werz, Oliver, Kries, Hajo, Gressler, Markus
Publicado 2022

Synbiotic Compositions of Bacillus megaterium and Polyunsaturated Fatty Acid Salt Enable Self-Sufficient Production of Specialized Pro-Resolving Mediators

por Speckmann, Bodo, Kleinbölting, Jessica, Börner, Friedemann, Jordan, Paul M., Werz, Oliver, Pelzer, Stefan, tom Dieck, Heike, Wagner, Tanja, Schön, Christiane
Publicado 2022

Beneficial Modulation of Lipid Mediator Biosynthesis in Innate Immune Cells by Antirheumatic Tripterygium wilfordii Glycosides

por Zhang, Kehong, Pace, Simona, Jordan, Paul M., Peltner, Lukas K., Weber, Alexander, Fischer, Dagmar, Hofstetter, Robert K., Chen, Xinchun, Werz, Oliver
Publicado 2021

Allosteric Activation of 15‐Lipoxygenase‐1 by Boswellic Acid Induces the Lipid Mediator Class Switch to Promote Resolution of Inflammation

por Börner, Friedemann, Pace, Simona, Jordan, Paul M., Gerstmeier, Jana, Gomez, Mario, Rossi, Antonietta, Gilbert, Nathaniel C., Newcomer, Marcia E., Werz, Oliver
Publicado 2022

Incidence and severity of G6PI-induced arthritis are not increased in genetically distinct mouse strains upon aging

por Andreas, Nico, Müller, Sylvia, Templin, Nicole, Jordan, Paul M., Schuhwerk, Harald, Müller, Michael, Gerstmeier, Jana, Miek, Laura, Andreas, Saskia, Werz, Oliver, Kamradt, Thomas
Publicado 2021

Establishment and Characterization of Mild Atopic Dermatitis in the DNCB-Induced Mouse Model

por Riedl, Rebecca, Kühn, Annika, Rietz, Denise, Hebecker, Betty, Glowalla, Karl-Gunther, Peltner, Lukas K., Jordan, Paul M., Werz, Oliver, Lorkowski, Stefan, Wiegand, Cornelia, Wallert, Maria
Publicado 2023

ATP/IL‐33‐triggered hyperactivation of mast cells results in an amplified production of pro‐inflammatory cytokines and eicosanoids

por Jordan, Paul M., Andreas, Nico, Groth, Marco, Wegner, Philine, Weber, Franziska, Jäger, Ute, Küchler, Claudia, Werz, Oliver, Serfling, Edgar, Kamradt, Thomas, Dudeck, Anne, Drube, Sebastian
Publicado 2021

The Natural Combination Medicine Traumeel (Tr14) Improves Resolution of Inflammation by Promoting the Biosynthesis of Specialized Pro-Resolving Mediators

por Jordan, Paul M., van Goethem, Emeline, Müller, Andrea M., Hemmer, Kathrin, Gavioli, Virginie, Baillif, Vincent, Burmeister, Yvonne, Krömmelbein, Natascha, Dubourdeau, Marc, Seilheimer, Bernd, Werz, Oliver
Publicado 2021

Sex Hormone–Dependent Lipid Mediator Formation in Male and Female Mice During Peritonitis

por Troisi, Fabiana, Pace, Simona, Jordan, Paul M., Meyer, Katharina P. L., Bilancia, Rossella, Ialenti, Armando, Borrelli, Francesca, Rossi, Antonietta, Sautebin, Lidia, Serhan, Charles N., Werz, Oliver
Publicado 2022

Osteocytes Serve as a Reservoir for Intracellular Persisting Staphylococcus aureus Due to the Lack of Defense Mechanisms

por Garcia-Moreno, Marina, Jordan, Paul M., Günther, Kerstin, Dau, Therese, Fritzsch, Christian, Vermes, Monika, Schoppa, Astrid, Ignatius, Anita, Wildemann, Britt, Werz, Oliver, Löffler, Bettina, Tuchscherr, Lorena
Publicado 2022

Staphylococcus aureus controls eicosanoid and specialized pro‐resolving mediator production via lipoteichoic acid

por Miek, Laura, Jordan, Paul M., Günther, Kerstin, Pace, Simona, Beyer, Timo, Kowalak, David, Hoerr, Verena, Löffler, Bettina, Tuchscherr, Lorena, Serhan, Charles N., Gerstmeier, Jana, Werz, Oliver
Publicado 2022

Ethoxy acetalated dextran nanoparticles for drug delivery: A comparative study of formulation methods

por Behnke, Mira, Klemm, Paul, Dahlke, Philipp, Shkodra, Blerina, Beringer-Siemers, Baerbel, Czaplewska, Justyna Anna, Stumpf, Steffi, Jordan, Paul M., Schubert, Stephanie, Hoeppener, Stephanie, Vollrath, Antje, Werz, Oliver, Schubert, Ulrich S.
Publicado 2023

Encapsulation of the dual FLAP/mPEGS-1 inhibitor BRP-187 into acetalated dextran and PLGA nanoparticles improves its cellular bioactivity

por Shkodra-Pula, Blerina, Kretzer, Christian, Jordan, Paul M., Klemm, Paul, Koeberle, Andreas, Pretzel, David, Banoglu, Erden, Lorkowski, Stefan, Wallert, Maria, Höppener, Stephanie, Stumpf, Steffi, Vollrath, Antje, Schubert, Stephanie, Werz, Oliver, Schubert, Ulrich S.
Publicado 2020

Lipid droplets control mitogenic lipid mediator production in human cancer cells

por Jovičić, Eva Jarc, Janež, Anja Pucer, Eichmann, Thomas O., Koren, Špela, Brglez, Vesna, Jordan, Paul M., Gerstmeier, Jana, Lainšček, Duško, Golob-Urbanc, Anja, Jerala, Roman, Lambeau, Gérard, Werz, Oliver, Zimmermann, Robert, Petan, Toni
Publicado 2023