Novel splice variants derived from the receptor tyrosine kinase superfamily are potential therapeutics for rheumatoid arthritis

por Jin, Pei, Zhang, Juan, Sumariwalla, Percy F, Ni, Irene, Jorgensen, Brett, Crawford, Damian, Phillips, Suzanne, Feldmann, Marc, Shepard, H Michael, Paleolog, Ewa M
Publicado 2008

PEGylated IL-10 Activates Kupffer Cells to Control Hypercholesterolemia

por Chan, Ivan H., Van Hoof, Dennis, Abramova, Marina, Bilardello, Melissa, Mar, Elliot, Jorgensen, Brett, McCauley, Scott, Bal, Harminder, Oft, Martin, Van Vlasselaer, Peter, Mumm, John B.
Publicado 2016

TNB-486 induces potent tumor cell cytotoxicity coupled with low cytokine release in preclinical models of B-NHL

por Malik-Chaudhry, Harbani K., Prabhakar, Kirthana, Ugamraj, Harshad S., Boudreau, Andrew A., Buelow, Benjamin, Dang, Kevin, Davison, Laura M., Harris, Katherine E., Jorgensen, Brett, Ogana, Heather, Pham, Duy, Schellenberger, Ute, Van Schooten, Wim, Buelow, Roland, Iyer, Suhasini, Trinklein, Nathan D., Rangaswamy, Udaya S.
Publicado 2021

Selective Allosteric Inhibition of MMP9 Is Efficacious in Preclinical Models of Ulcerative Colitis and Colorectal Cancer

por Marshall, Derek C., Lyman, Susan K., McCauley, Scott, Kovalenko, Maria, Spangler, Rhyannon, Liu, Chian, Lee, Michael, O’Sullivan, Christopher, Barry-Hamilton, Vivian, Ghermazien, Haben, Mikels-Vigdal, Amanda, Garcia, Carlos A., Jorgensen, Brett, Velayo, Arleene C., Wang, Ruth, Adamkewicz, Joanne I., Smith, Victoria
Publicado 2015

Efficient tumor killing and minimal cytokine release with novel T-cell agonist bispecific antibodies

por Trinklein, Nathan D., Pham, Duy, Schellenberger, Ute, Buelow, Ben, Boudreau, Andrew, Choudhry, Priya, Clarke, Starlynn C., Dang, Kevin, Harris, Katherine E., Iyer, Suhasini, Jorgensen, Brett, Pratap, Payal P., Rangaswamy, Udaya S., Ugamraj, Harshad S., Vafa, Omid, Wiita, Arun P., van Schooten, Wim, Buelow, Roland, Force Aldred, Shelley
Publicado 2019

Sequence-Based Discovery Demonstrates That Fixed Light Chain Human Transgenic Rats Produce a Diverse Repertoire of Antigen-Specific Antibodies

por Harris, Katherine E., Aldred, Shelley Force, Davison, Laura M., Ogana, Heather Anne N., Boudreau, Andrew, Brüggemann, Marianne, Osborn, Michael, Ma, Biao, Buelow, Benjamin, Clarke, Starlynn C., Dang, Kevin H., Iyer, Suhasini, Jorgensen, Brett, Pham, Duy T., Pratap, Payal P., Rangaswamy, Udaya S., Schellenberger, Ute, van Schooten, Wim C., Ugamraj, Harshad S., Vafa, Omid, Buelow, Roland, Trinklein, Nathan D.
Publicado 2018

Multispecific Antibody Development Platform Based on Human Heavy Chain Antibodies

por Clarke, Starlynn C., Ma, Biao, Trinklein, Nathan D., Schellenberger, Ute, Osborn, Michael J., Ouisse, Laure-Hélène, Boudreau, Andrew, Davison, Laura M., Harris, Katherine E., Ugamraj, Harshad S., Balasubramani, Aarti, Dang, Kevin H., Jorgensen, Brett, Ogana, Heather Anne N., Pham, Duy T., Pratap, Payal P., Sankaran, Preethi, Anegon, Ignacio, van Schooten, Wim C., Brüggemann, Marianne, Buelow, Roland, Force Aldred, Shelley
Publicado 2019