Evaluation of Muscle microRNA Expression in Relation to Human Peripheral Insulin Sensitivity: A Cross-Sectional Study in Metabolically Distinct Subject Groups

por Dahlmans, Dennis, Houzelle, Alexandre, Jörgensen, Johanna A., Phielix, Esther, Lindeboom, Lucas, Hesselink, Matthijs K. C., Schrauwen, Patrick, Hoeks, Joris
Publicado 2017

An unbiased silencing screen in muscle cells identifies miR-320a, miR-150, miR-196b, and miR-34c as regulators of skeletal muscle mitochondrial metabolism

por Dahlmans, Dennis, Houzelle, Alexandre, Andreux, Pénélope, Jörgensen, Johanna A., Wang, Xu, de Windt, Leon J., Schrauwen, Patrick, Auwerx, Johan, Hoeks, Joris
Publicado 2017

MicroRNA‐382 silencing induces a mitonuclear protein imbalance and activates the mitochondrial unfolded protein response in muscle cells

por Dahlmans, Dennis, Houzelle, Alexandre, Andreux, Pénélope, Wang, Xu, Jörgensen, Johanna A., Moullan, Norman, Daemen, Sabine, Kersten, Sander, Auwerx, Johan, Hoeks, Joris
Publicado 2018

MicroRNA‐204‐5p modulates mitochondrial biogenesis in C2C12 myotubes and associates with oxidative capacity in humans

por Houzelle, Alexandre, Dahlmans, Dennis, Nascimento, Emmani B. M., Schaart, Gert, Jörgensen, Johanna A., Moonen‐Kornips, Esther, Kersten, Sander, Wang, Xu, Hoeks, Joris
Publicado 2020

Human skeletal muscle mitochondrial dynamics in relation to oxidative capacity and insulin sensitivity

por Houzelle, Alexandre, Jörgensen, Johanna A., Schaart, Gert, Daemen, Sabine, van Polanen, Nynke, Fealy, Ciarán E., Hesselink, Matthijs K. C., Schrauwen, Patrick, Hoeks, Joris
Publicado 2020

A genistein-enriched diet neither improves skeletal muscle oxidative capacity nor prevents the transition towards advanced insulin resistance in ZDF rats

por van Bree, Bianca W. J., Lenaers, Ellen, Nabben, Miranda, Briedé, Jacco J., Jörgensen, Johanna A., Schaart, Gert, Schrauwen, Patrick, Hoeks, Joris, Hesselink, Matthijs K. C.
Publicado 2016

Twenty-four hour rhythmicity in mitochondrial network connectivity and mitochondrial respiration; a study in human skeletal muscle biopsies of young lean and older individuals with...

por Gemmink, Anne, Daemen, Sabine, Wefers, Jakob, Hansen, Jan, van Moorsel, Dirk, Astuti, Puji, Jorgensen, Johanna A., Kornips, Esther, Schaart, Gert, Hoeks, Joris, Schrauwen, Patrick, Hesselink, Matthijs K.C.
Publicado 2023

ANT1-mediated fatty acid-induced uncoupling as a target for improving myocellular insulin sensitivity

por Sparks, Lauren M., Gemmink, Anne, Phielix, Esther, Bosma, Madeleen, Schaart, Gert, Moonen-Kornips, Esther, Jörgensen, Johanna A., Nascimento, Emmani B. M., Hesselink, Matthijs K. C., Schrauwen, Patrick, Hoeks, Joris
Publicado 2016

Day-night rhythm of skeletal muscle metabolism is disturbed in older, metabolically compromised individuals

por Wefers, Jakob, Connell, Niels J., Fealy, Ciarán E., Andriessen, Charlotte, de Wit, Vera, van Moorsel, Dirk, Moonen-Kornips, Esther, Jörgensen, Johanna A., Hesselink, Matthijs K.C., Havekes, Bas, Hoeks, Joris, Schrauwen, Patrick
Publicado 2020

Demonstration of a day-night rhythm in human skeletal muscle oxidative capacity

por van Moorsel, Dirk, Hansen, Jan, Havekes, Bas, Scheer, Frank A.J.L., Jörgensen, Johanna A., Hoeks, Joris, Schrauwen-Hinderling, Vera B., Duez, Helene, Lefebvre, Philippe, Schaper, Nicolaas C., Hesselink, Matthijs K.C., Staels, Bart, Schrauwen, Patrick
Publicado 2016

One-leg inactivity induces a reduction in mitochondrial oxidative capacity, intramyocellular lipid accumulation and reduced insulin signalling upon lipid infusion: a human study wi...

por Bilet, Lena, Phielix, Esther, van de Weijer, Tineke, Gemmink, Anne, Bosma, Madeleen, Moonen-Kornips, Esther, Jorgensen, Johanna A., Schaart, Gert, Zhang, Dongyan, Meijer, Kenneth, Hopman, Maria, Hesselink, Matthijs K. C., Ouwens, D. Margriet, Shulman, Gerald I., Schrauwen-Hinderling, Vera B., Schrauwen, Patrick
Publicado 2020

PCr/ATP ratios and mitochondrial function in the heart. A comparative study in humans

por de Wit-Verheggen, Vera H. W., Schrauwen-Hinderling, Vera B., Brouwers, Kim, Jörgensen, Johanna A., Schaart, Gert, Gemmink, Anne, Nascimento, Emmani B. M., Hesselink, Matthijs K. C., Wildberger, Joachim E., Segers, Patrique, Montaigne, David, Staels, Bart, Schrauwen, Patrick, Lindeboom, Lucas, Hoeks, Joris, van de Weijer, Tineke
Publicado 2023

Sitting less elicits metabolic responses similar to exercise and enhances insulin sensitivity in postmenopausal women

por Remie, Carlijn M. E., Janssens, Georges E., Bilet, Lena, van Weeghel, Michel, Duvivier, Bernard M. F. M., de Wit, Vera H. W., Connell, Niels J., Jörgensen, Johanna A., Schomakers, Bauke V., Schrauwen-Hinderling, Vera B., Hoeks, Joris, Hesselink, Matthijs K. C., Phielix, Esther, Houtkooper, Riekelt H., Schrauwen, Patrick
Publicado 2021

Effects of SGLT2 inhibitor dapagliflozin in patients with type 2 diabetes on skeletal muscle cellular metabolism

por op den Kamp, Yvo J.M., Gemmink, Anne, de Ligt, Marlies, Dautzenberg, Bas, Kornips, Esther, Jorgensen, Johanna A., Schaart, Gert, Esterline, Russell, Pava, Diego A., Hoeks, Joris, Schrauwen-Hinderling, Vera B., Kersten, Sander, Havekes, Bas, Koves, Timothy R., Muoio, Deborah M., Hesselink, Matthijs K.C., Oscarsson, Jan, Phielix, Esther, Schrauwen, Patrick
Publicado 2022

Effect of β2-agonist treatment on insulin-stimulated peripheral glucose disposal in healthy men in a randomised placebo-controlled trial

por van Beek, Sten M. M., Bruls, Yvonne M. H., Vanweert, Froukje, Fealy, Ciarán E., Connell, Niels J., Schaart, Gert, Moonen-Kornips, Esther, Jörgensen, Johanna A., Vaz, Frédéric M., Smeets, Ellen T. H. C., Joris, Peter J., Gemmink, Anne, Houtkooper, Riekelt H., Hesselink, Matthijs K. C., Bengtsson, Tore, Havekes, Bas, Schrauwen, Patrick, Hoeks, Joris
Publicado 2023