Drp1/Fis1 interaction mediates mitochondrial dysfunction, bioenergetic failure and cognitive decline in Alzheimer's disease

por Joshi, Amit U., Saw, Nay L., Shamloo, Mehrdad, Mochly-Rosen, Daria
Publicado 2017

Mitochondrial dysfunction mediated through dynamin-related protein 1 (Drp1) propagates impairment in blood brain barrier in septic encephalopathy

por Haileselassie, Bereketeab, Joshi, Amit U., Minhas, Paras S., Mukherjee, Riddhita, Andreasson, Katrin I., Mochly-Rosen, Daria
Publicado 2020

Inhibition of Drp1/Fis1 interaction slows progression of amyotrophic lateral sclerosis

por Joshi, Amit U, Saw, Nay L, Vogel, Hannes, Cunnigham, Anna D, Shamloo, Mehrdad, Mochly‐Rosen, Daria
Publicado 2018

Potential biomarkers to follow the progression and treatment response of Huntington’s disease

por Disatnik, Marie-Hélène, Joshi, Amit U., Saw, Nay L., Shamloo, Mehrdad, Leavitt, Blair R., Qi, Xin, Mochly-Rosen, Daria
Publicado 2016

Fragmented mitochondria released from microglia trigger A1 astrocytic response and propagate inflammatory neurodegeneration

por Joshi, Amit U., Minhas, Paras S., Liddelow, Shane A., Haileselassie, Bereketeab, Andreasson, Katrin I., Dorn II, Gerald W., Mochly-Rosen, Daria
Publicado 2019

Aldehyde dehydrogenase 2 activity and aldehydic load contribute to neuroinflammation and Alzheimer’s disease related pathology

por Joshi, Amit U., Van Wassenhove, Lauren D., Logas, Kelsey R., Minhas, Paras S., Andreasson, Katrin I., Weinberg, Kenneth I., Chen, Che-Hong, Mochly-Rosen, Daria
Publicado 2019

Novel and prevalent non-East Asian ALDH2 variants; Implications for global susceptibility to aldehydes’ toxicity

por Chen, Che-Hong, Ferreira, Julio C.B., Joshi, Amit U., Stevens, Matthew C., Li, Sin-Jin, Hsu, Jade H.-M., Maclean, Rory, Ferreira, Nikolas D., Cervantes, Pilar R., Martinez, Diana D., Barrientos, Fernando L., Quintanares, Gibran H.R., Mochly-Rosen, Daria
Publicado 2020