Dispatches from the functional phase of genome biology

por Jostins, Luke
Publicado 2012

Reverse engineering a gene network using an asynchronous parallel evolution strategy

por Jostins, Luke, Jaeger, Johannes
Publicado 2010

Genetic risk prediction in complex disease

por Jostins, Luke, Barrett, Jeffrey C.
Publicado 2011

Trinculo: Bayesian and frequentist multinomial logistic regression for genome-wide association studies of multi-category phenotypes

por Jostins, Luke, McVean, Gilean
Publicado 2016

Graphical Model Selection for Gaussian Conditional Random Fields in the Presence of Latent Variables

por Frot, Benjamin, Jostins, Luke, McVean, Gilean
Publicado 2018

Using Genetic Prediction from Known Complex Disease Loci to Guide the Design of Next-Generation Sequencing Experiments

por Jostins, Luke, Levine, Adam P., Barrett, Jeffrey C.
Publicado 2013

Next-generation sequencing and the era of personal Y genomes

por Ayub, Qasim, Jostins, Luke, Xue, Yali, Turner, Daniel, Tyler-Smith, Chris
Publicado 2010

Comparison of LABORAS with static incapacitance testing for assessing spontaneous pain behaviour in surgically-induced murine osteoarthritis

por von Loga, Isabell S., Miotla-Zarebska, Jadwiga, Huang, Yi-Shu, Williams, Richard, Jostins, Luke, Vincent, Tonia L.
Publicado 2020

Genomic profiling of T-cell activation suggests increased sensitivity of memory T cells to CD28 costimulation

por Glinos, Dafni A., Soskic, Blagoje, Williams, Cayman, Kennedy, Alan, Jostins, Luke, Sansom, David M., Trynka, Gosia
Publicado 2020

Bayesian analysis of genetic association across tree-structured routine healthcare data in the UK Biobank

por Cortes, Adrian, Dendrou, Calliope A., Motyer, Allan, Jostins, Luke, Vukcevic, Damjan, Dilthey, Alexander, Donnelly, Peter, Leslie, Stephen, Fugger, Lars, McVean, Gil
Publicado 2017

Active immunisation targeting nerve growth factor attenuates chronic pain behaviour in murine osteoarthritis

por von Loga, Isabell S, El-Turabi, Aadil, Jostins, Luke, Miotla-Zarebska, Jadwiga, Mackay-Alderson, Jennifer, Zeltins, Andris, Parisi, Ida, Bachmann, Martin F, Vincent, Tonia L
Publicado 2019

Genetic Complexity of Crohn’s Disease in Two Large Ashkenazi Jewish Families

por Levine, Adam P., Pontikos, Nikolas, Schiff, Elena R., Jostins, Luke, Speed, Doug, Lovat, Laurence B., Barrett, Jeffrey C., Grasberger, Helmut, Plagnol, Vincent, Segal, Anthony W.
Publicado 2016

Defective tumor necrosis factor release from Crohn's disease macrophages in response to toll-like receptor activation: Relationship to phenotype and genome-wide association suscept...

por Sewell, Gavin W, Rahman, Farooq Z, Levine, Adam P, Jostins, Luke, Smith, Philip J, Walker, Ann P, Bloom, Stuart L, Segal, Anthony W, Smith, Andrew M
Publicado 2012

Mapping autophagosome contents identifies interleukin-7 receptor-α as a key cargo modulating CD4+ T cell proliferation

por Zhou, Dingxi, Borsa, Mariana, Puleston, Daniel J., Zellner, Susanne, Capera, Jesusa, Sanderson, Sharon, Schifferer, Martina, Hester, Svenja S., Ge, Xin, Fischer, Roman, Jostins, Luke, Behrends, Christian, Alsaleh, Ghada, Simon, Anna Katharina
Publicado 2022

Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis

por Liu, Jimmy Z, Almarri, Mohamed A, Gaffney, Daniel J, Mells, George F, Jostins, Luke, Cordell, Heather J, Ducker, Samantha J, Day, Darren B, Heneghan, Michael A, Neuberger, James M., Donaldson, Peter T, Bathgate, Andrew J, Burroughs, Andrew, Davies, Mervyn H, Jones, David E, Alexander, Graeme J, Barrett, Jeffrey C, Sandford, Richard N, Anderson, Carl A
Publicado 2012

GWAS of stool frequency provides insights into gastrointestinal motility and irritable bowel syndrome

por Bonfiglio, Ferdinando, Liu, Xingrong, Smillie, Christopher, Pandit, Anita, Kurilshikov, Alexander, Bacigalupe, Rodrigo, Zheng, Tenghao, Nim, Hieu, Garcia-Etxebarria, Koldo, Bujanda, Luis, Andreasson, Anna, Agreus, Lars, Walter, Susanna, Abecasis, Gonçalo, Eijsbouts, Chris, Jostins, Luke, Parkes, Miles, Hughes, David A., Timpson, Nicholas, Raes, Jeroen, Franke, Andre, Kennedy, Nicholas A., Regev, Aviv, Zhernakova, Alexandra, Simren, Magnus, Camilleri, Michael, D’Amato, Mauro
Publicado 2021

High density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis

por Goyette, Philippe, Boucher, Gabrielle, Mallon, Dermot, Ellinghaus, Eva, Jostins, Luke, Huang, Hailiang, Ripke, Stephan, Gusareva, Elena S, Annese, Vito, Hauser, Stephen L, Oksenberg, Jorge R, Thomsen, Ingo, Leslie, Stephen, Daly, Mark J, Van Steen, Kristel, Duerr, Richard H, Barrett, Jeffrey C, McGovern, Dermot PB, Schumm, L Philip, Traherne, James A, Carrington, Mary N, Kosmoliaptsis, Vasilis, Karlsen, Tom H, Franke, Andre, Rioux, John D
Publicado 2015

Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders

por Eijsbouts, Chris, Zheng, Tenghao, Kennedy, Nicholas A., Bonfiglio, Ferdinando, Anderson, Carl A., Moutsianas, Loukas, Holliday, Joanne, Shi, Jingchunzi, Shringarpure, Suyash, Voda, Alexandru-Ioan, Farrugia, Gianrico, Franke, Andre, Hübenthal, Matthias, Abecasis, Gonçalo, Zawistowski, Matthew, Skogholt, Anne Heidi, Ness-Jensen, Eivind, Hveem, Kristian, Esko, Tõnu, Teder-Laving, Maris, Zhernakova, Alexandra, Camilleri, Michael, Boeckxstaens, Guy, Whorwell, Peter J., Spiller, Robin, McVean, Gil, D’Amato, Mauro, Jostins, Luke, Parkes, Miles
Publicado 2021

Exploring the genetic architecture of inflammatory bowel disease by whole genome sequencing identifies association at ADCY7

por Luo, Yang, de Lange, Katrina M., Jostins, Luke, Moutsianas, Loukas, Randall, Joshua, Kennedy, Nicholas A., Lamb, Christopher A., McCarthy, Shane, Ahmad, Tariq, Edwards, Cathryn, Serra, Eva Goncalves, Hart, Ailsa, Hawkey, Chris, Mansfield, John C., Mowat, Craig, Newman, William G., Nichols, Sam, Pollard, Martin, Satsangi, Jack, Simmons, Alison, Tremelling, Mark, Uhlig, Holm, Wilson, David C., Lee, James C., Prescott, Natalie J., Lees, Charlie W., Mathew, Christopher G., Parkes, Miles, Barrett, Jeffrey C., Anderson, Carl A.
Publicado 2017

Imputation-Based Meta-Analysis of Severe Malaria in Three African Populations

por Band, Gavin, Le, Quang Si, Jostins, Luke, Pirinen, Matti, Kivinen, Katja, Jallow, Muminatou, Sisay-Joof, Fatoumatta, Bojang, Kalifa, Pinder, Margaret, Sirugo, Giorgio, Conway, David J., Nyirongo, Vysaul, Kachala, David, Molyneux, Malcolm, Taylor, Terrie, Ndila, Carolyne, Peshu, Norbert, Marsh, Kevin, Williams, Thomas N., Alcock, Daniel, Andrews, Robert, Edkins, Sarah, Gray, Emma, Hubbart, Christina, Jeffreys, Anna, Rowlands, Kate, Schuldt, Kathrin, Clark, Taane G., Small, Kerrin S., Teo, Yik Ying, Kwiatkowski, Dominic P., Rockett, Kirk A., Barrett, Jeffrey C., Spencer, Chris C. A.
Publicado 2013