Multiplexed relative and absolute quantitative immunopeptidomics reveals MHC I repertoire alterations induced by CDK4/6 inhibition

por Stopfer, Lauren E., Mesfin, Joshua M., Joughin, Brian A., Lauffenburger, Douglas A., White, Forest M.
Publicado 2020

An in vitro intestinal model captures immunomodulatory properties of the microbiota in inflammation

por Lock, Jaclyn Y., Caboni, Mariaelena, Strandwitz, Philip, Morrissette, Madeleine, DiBona, Kevin, Joughin, Brian A., Lewis, Kim, Carrier, Rebecca L.
Publicado 2022

Low Doses of Arsenic in a Mouse Model of Human Exposure and in Neuronal Culture Lead to S-Nitrosylation of Synaptic Proteins and Apoptosis via Nitric Oxide

por Amal, Haitham, Gong, Guanyu, Yang, Hongmei, Joughin, Brian A., Wang, Xin, Knutson, Charles G., Kartawy, Maryam, Khaliulin, Igor, Wishnok, John S., Tannenbaum, Steven R.
Publicado 2020

A genome-scale in vivo loss-of-function screen identifies Phf6 as a lineage-specific regulator of leukemia cell growth

por Meacham, Corbin E., Lawton, Lee N., Soto-Feliciano, Yadira M., Pritchard, Justin R., Joughin, Brian A., Ehrenberger, Tobias, Fenouille, Nina, Zuber, Johannes, Williams, Richard T., Young, Richard A., Hemann, Michael T.
Publicado 2015

Comprehensive substrate specificity profiling of the human Nek kinome reveals unexpected signaling outputs

por van de Kooij, Bert, Creixell, Pau, van Vlimmeren, Anne, Joughin, Brian A, Miller, Chad J, Haider, Nasir, Simpson, Craig D, Linding, Rune, Stambolic, Vuk, Turk, Benjamin E, Yaffe, Michael B
Publicado 2019

Robustness and applicability of transcription factor and pathway analysis tools on single-cell RNA-seq data

por Holland, Christian H., Tanevski, Jovan, Perales-Patón, Javier, Gleixner, Jan, Kumar, Manu P., Mereu, Elisabetta, Joughin, Brian A., Stegle, Oliver, Lauffenburger, Douglas A., Heyn, Holger, Szalai, Bence, Saez-Rodriguez, Julio
Publicado 2020

Transite: A Computational Motif-Based Analysis Platform That Identifies RNA-Binding Proteins Modulating Changes in Gene Expression

por Krismer, Konstantin, Bird, Molly A., Varmeh, Shohreh, Handly, Erika D., Gattinger, Anna, Bernwinkler, Thomas, Anderson, Daniel A., Heinzel, Andreas, Joughin, Brian A., Kong, Yi Wen, Cannell, Ian G., Yaffe, Michael B.
Publicado 2020

Phosphoproteomics identifies microglial Siglec‐F inflammatory response during neurodegeneration

por Morshed, Nader, Ralvenius, William T, Nott, Alexi, Watson, L Ashley, Rodriguez, Felicia H, Akay, Leyla A, Joughin, Brian A, Pao, Ping‐Chieh, Penney, Jay, LaRocque, Lauren, Mastroeni, Diego, Tsai, Li‐Huei, White, Forest M
Publicado 2020

The Fanconi anemia core complex promotes CtIP-dependent end-resection to drive homologous recombination at DNA double-strand breaks

por van de Kooij, Bert, van der Wal, Fenna J., Rother, Magdalena B., Creixell, Pau, Stout, Merula, Wiegant, Wouter, Joughin, Brian A., Vornberger, Julia, van Vugt, Marcel A.T.M., Altmeyer, Matthias, Yaffe, Michael B., van Attikum, Haico
Publicado 2023

PTP1B-dependent regulation of receptor tyrosine kinase signaling by the actin-binding protein Mena

por Hughes, Shannon K., Oudin, Madeleine J., Tadros, Jenny, Neil, Jason, Del Rosario, Amanda, Joughin, Brian A., Ritsma, Laila, Wyckoff, Jeff, Vasile, Eliza, Eddy, Robert, Philippar, Ulrike, Lussiez, Alisha, Condeelis, John S., van Rheenen, Jacco, White, Forest, Lauffenburger, Douglas A., Gertler, Frank B.
Publicado 2015

Cancer-Associated Fibroblasts and Squamous Epithelial Cells Constitute a Unique Microenvironment in a Mouse Model of Inflammation-Induced Colon Cancer

por Vega, Paige N., Nilsson, Avlant, Kumar, Manu P., Niitsu, Hiroaki, Simmons, Alan J., Ro, James, Wang, Jiawei, Chen, Zhengyi, Joughin, Brian A., Li, Wei, McKinley, Eliot T., Liu, Qi, Roland, Joseph T., Washington, M. Kay, Coffey, Robert J., Lauffenburger, Douglas A., Lau, Ken S.
Publicado 2022

Proteomics of Coagulopathy Following Injury Reveals Limitations of Using Laboratory Assessment to Define Trauma-Induced Coagulopathy to Predict Massive Transfusion

por Moore, Hunter B., Neal, Matthew D., Bertolet, Marnie, Joughin, Brian A., Yaffe, Michael B., Barrett, Christopher D., Bird, Molly A., Tracy, Russell P., Moore, Ernest E, Sperry, Jason L., Zuckerbraun, Brian S., Park, Myung S., Cohen, Mitchell J., Wisniewski, Stephen R., Morrissey, James H.
Publicado 2022

Integrated mapping of pharmacokinetics and pharmacodynamics in a patient-derived xenograft model of glioblastoma

por Randall, Elizabeth C., Emdal, Kristina B., Laramy, Janice K., Kim, Minjee, Roos, Alison, Calligaris, David, Regan, Michael S., Gupta, Shiv K., Mladek, Ann C., Carlson, Brett L., Johnson, Aaron J., Lu, Fa-Ke, Xie, X. Sunney, Joughin, Brian A., Reddy, Raven J., Peng, Sen, Abdelmoula, Walid M., Jackson, Pamela R., Kolluri, Aarti, Kellersberger, Katherine A., Agar, Jeffrey N., Lauffenburger, Douglas A., Swanson, Kristin R., Tran, Nhan L., Elmquist, William F., White, Forest M., Sarkaria, Jann N., Agar, Nathalie Y. R.
Publicado 2018