In Vitro Infection with Hepatitis B Virus Using Differentiated Human Serum Culture of Huh7.5-NTCP Cells without Requiring Dimethyl Sulfoxide

por Le, Connie, Sirajee, Reshma, Steenbergen, Rineke, Joyce, Michael A., Addison, William R., Tyrrell, D. Lorne
Publicado 2021

Multiplex Assays Enable Simultaneous Detection and Identification of SARS-CoV-2 Variants of Concern in Clinical and Wastewater Samples

por Liu, Yanming, Kumblathan, Teresa, Joyce, Michael A., Tyrrell, D. Lorne, Tipples, Graham, Pang, Xiaoli, Li, Xing-Fang, Le, X. Chris
Publicado 2023

HCV and flaviviruses hijack cellular mechanisms for nuclear STAT2 degradation: Up-regulation of PDLIM2 suppresses the innate immune response

por Joyce, Michael A., Berry-Wynne, Karyn M., dos Santos, Theodore, Addison, William R., McFarlane, Nicola, Hobman, Tom, Tyrrell, D. Lorne
Publicado 2019

Hepatitis C Virus-Induced Cytoplasmic Organelles Use the Nuclear Transport Machinery to Establish an Environment Conducive to Virus Replication

por Neufeldt, Christopher J., Joyce, Michael A., Levin, Aviad, Steenbergen, Rineke H., Pang, Daniel, Shields, Justin, Tyrrell, D. Lorne J., Wozniak, Richard W.
Publicado 2013

Functional Characterization of Nuclear Localization and Export Signals in Hepatitis C Virus Proteins and Their Role in the Membranous Web

por Levin, Aviad, Neufeldt, Christopher J., Pang, Daniel, Wilson, Kristen, Loewen-Dobler, Darci, Joyce, Michael A., Wozniak, Richard W., Tyrrell, D. Lorne J
Publicado 2014

The Hepatitis C Virus-Induced Membranous Web and Associated Nuclear Transport Machinery Limit Access of Pattern Recognition Receptors to Viral Replication Sites

por Neufeldt, Christopher J., Joyce, Michael A., Van Buuren, Nicholas, Levin, Aviad, Kirkegaard, Karla, Gale Jr., Michael, Tyrrell, D. Lorne J., Wozniak, Richard W.
Publicado 2016

Application of functional genomics to the chimeric mouse model of HCV infection: optimization of microarray protocols and genomics analysis

por Walters, Kathie-Anne, Joyce, Michael A, Thompson, Jill C, Proll, Sean, Wallace, James, Smith, Maria W, Furlong, Jeff, Tyrrell, D Lorne, Katze, Michael G
Publicado 2006

Interferon regulatory factor 3 mediates effective antiviral responses to human coronavirus 229E and OC43 infection

por Duncan, Joseph K. Sampson, Xu, Danyang, Licursi, Maria, Joyce, Michael A., Saffran, Holly A., Liu, Kaiwen, Gohda, Jin, Tyrrell, D. Lorne, Kawaguchi, Yasushi, Hirasawa, Kensuke
Publicado 2023

HCV Induces Oxidative and ER Stress, and Sensitizes Infected Cells to Apoptosis in SCID/Alb-uPA Mice

por Joyce, Michael A., Walters, Kathie-Anne, Lamb, Sue-Ellen, Yeh, Mathew M., Zhu, Lin-Fu, Kneteman, Norman, Doyle, Jason S., Katze, Michael G., Tyrrell, D. Lorne
Publicado 2009

On-Site Viral Inactivation and RNA Preservation of Gargle and Saliva Samples Combined with Direct Analysis of SARS-CoV-2 RNA on Magnetic Beads

por Liu, Yanming, Kumblathan, Teresa, Feng, Wei, Pang, Bo, Tao, Jeffrey, Xu, Jingyang, Xiao, Huyan, Joyce, Michael A., Tyrrell, D. Lorne, Zhang, Hongquan, Li, Xing-Fang, Le, X. Chris
Publicado 2022

Host-Specific Response to HCV Infection in the Chimeric SCID-beige/Alb-uPA Mouse Model: Role of the Innate Antiviral Immune Response

por Walters, Kathie-Anne, Joyce, Michael A, Thompson, Jill C, Smith, Maria W, Yeh, Matthew M, Proll, Sean, Zhu, Lin-Fu, Gao, T. J, Kneteman, Norman M, Tyrrell, D. Lorne, Katze, Michael G
Publicado 2006

Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication

por Vuong, Wayne, Khan, Muhammad Bashir, Fischer, Conrad, Arutyunova, Elena, Lamer, Tess, Shields, Justin, Saffran, Holly A., McKay, Ryan T., van Belkum, Marco J., Joyce, Michael A., Young, Howard S., Tyrrell, D. Lorne, Vederas, John C., Lemieux, M. Joanne
Publicado 2020

Author Correction: Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication

por Vuong, Wayne, Khan, Muhammad Bashir, Fischer, Conrad, Arutyunova, Elena, Lamer, Tess, Shields, Justin, Saffran, Holly A., McKay, Ryan T., van Belkum, Marco J., Joyce, Michael A., Young, Howard S., Tyrrell, D. Lorne, Vederas, John C., Lemieux, M. Joanne
Publicado 2020

Improved SARS-CoV-2 M(pro) inhibitors based on feline antiviral drug GC376: Structural enhancements, increased solubility, and micellar studies

por Vuong, Wayne, Fischer, Conrad, Khan, Muhammad Bashir, van Belkum, Marco J., Lamer, Tess, Willoughby, Kurtis D., Lu, Jimmy, Arutyunova, Elena, Joyce, Michael A., Saffran, Holly A., Shields, Justin A., Young, Howard S., Nieman, James A., Tyrrell, D. Lorne, Lemieux, M. Joanne, Vederas, John C.
Publicado 2021

IL-28B is a Key Regulator of B- and T-Cell Vaccine Responses against Influenza

por Egli, Adrian, Santer, Deanna M., O'Shea, Daire, Barakat, Khaled, Syedbasha, Mohammedyaseen, Vollmer, Madeleine, Baluch, Aliyah, Bhat, Rakesh, Groenendyk, Jody, Joyce, Michael A., Lisboa, Luiz F., Thomas, Brad S., Battegay, Manuel, Khanna, Nina, Mueller, Thomas, Tyrrell, D. Lorne J., Houghton, Michael, Humar, Atul, Kumar, Deepali
Publicado 2014

SARS-COV-2 recombinant Receptor-Binding-Domain (RBD) induces neutralizing antibodies against variant strains of SARS-CoV-2 and SARS-CoV-1

por Law, John Lok Man, Logan, Michael, Joyce, Michael A., Landi, Abdolamir, Hockman, Darren, Crawford, Kevin, Johnson, Janelle, LaChance, Gerald, Saffran, Holly A., Shields, Justin, Hobart, Eve, Brassard, Raelynn, Arutyunova, Elena, Pabbaraju, Kanti, Croxen, Matthew, Tipples, Graham, Lemieux, M. Joanne, Tyrrell, D. Lorne, Houghton, Michael
Publicado 2021

Antibodies to neutralising epitopes synergistically block the interaction of the receptor‐binding domain of SARS‐CoV‐2 to ACE 2

por Pandey, Manisha, Ozberk, Victoria, Eskandari, Sharareh, Shalash, Ahmed O, Joyce, Michael A, Saffran, Holly A, Day, Christopher J, Lepletier, Ailin, Spillings, Belinda L, Mills, Jamie‐Lee, Calcutt, Ainslie, Fan, Fan, Williams, James T, Stanisic, Danielle I, Hattingh, Laetitia, Gerrard, John, Skwarczynski, Mariusz, Mak, Johnson, Jennings, Michael P, Toth, Istvan, Tyrrell, D Lorne, Good, Michael F
Publicado 2021

Two DNA vaccines protect against severe disease and pathology due to SARS-CoV-2 in Syrian hamsters

por Babuadze, George Giorgi, Fausther-Bovendo, Hugues, deLaVega, Marc-Antoine, Lillie, Brandon, Naghibosadat, Maedeh, Shahhosseini, Nariman, Joyce, Michael A., Saffran, Holly A., Lorne Tyrrell, D., Falzarano, Darryl, Senthilkumaran, Chandrika, Christie-Holmes, Natasha, Ahn, Steven, Gray-Owen, Scott D., Banerjee, Arinjay, Mubareka, Samira, Mossman, Karen, Dupont, Chanel, Pedersen, Jannie, Lafrance, Mark-Alexandre, Kobinger, Gary P., Kozak, Robert
Publicado 2022