Supercoiling and looping promote DNA base accessibility and coordination among distant sites

por Fogg, Jonathan M., Judge, Allison K., Stricker, Erik, Chan, Hilda L., Zechiedrich, Lynn
Publicado 2021

Mapping the determinants of catalysis and substrate specificity of the antibiotic resistance enzyme CTX-M β-lactamase

por Judge, Allison, Hu, Liya, Sankaran, Banumathi, Van Riper, Justin, Venkataram Prasad, B. V., Palzkill, Timothy
Publicado 2023

An active site loop toggles between conformations to control antibiotic hydrolysis and inhibition potency for CTX-M β-lactamase drug-resistance enzymes

por Lu, Shuo, Hu, Liya, Lin, Hanfeng, Judge, Allison, Rivera, Paola, Palaniappan, Murugesan, Sankaran, Banumathi, Wang, Jin, Prasad, B. V. Venkataram, Palzkill, Timothy
Publicado 2022

DNA-encoded chemical libraries yield non-covalent and non-peptidic SARS-CoV-2 main protease inhibitors

por Jimmidi, Ravikumar, Chamakuri, Srinivas, Lu, Shuo, Ucisik, Melek Nihan, Chen, Peng-Jen, Bohren, Kurt M., Moghadasi, Seyed Arad, Versteeg, Leroy, Nnabuife, Christina, Li, Jian-Yuan, Qin, Xuan, Chen, Ying-Chu, Faver, John C., Nyshadham, Pranavanand, Sharma, Kiran L., Sankaran, Banumathi, Judge, Allison, Yu, Zhifeng, Li, Feng, Pollet, Jeroen, Harris, Reuben S., Matzuk, Martin M., Palzkill, Timothy, Young, Damian W.
Publicado 2023