Retinal Pigment Epithelium and Photoreceptor Preconditioning Protection Requires Docosanoid Signaling

por Knott, Eric J., Gordon, William C., Jun, Bokkyoo, Do, Khanh, Bazan, Nicolas G.
Publicado 2017

Defining a mechanistic link between pigment epithelium–derived factor, docosahexaenoic acid, and corneal nerve regeneration

por Pham, Thang Luong, He, Jiucheng, Kakazu, Azucena H., Jun, Bokkyoo, Bazan, Nicolas G., Bazan, Haydee E. P.
Publicado 2017

Novel RvD6 stereoisomer induces corneal nerve regeneration and wound healing post-injury by modulating trigeminal transcriptomic signature

por Pham, Thang L., Kakazu, Azucena H., He, Jiucheng, Jun, Bokkyoo, Bazan, Nicolas G., Bazan, Haydee E. P.
Publicado 2020

Microglial ramification and redistribution concomitant with the attenuation of choroidal neovascularization by neuroprotectin D1

por Sheets, Kristopher G., Jun, Bokkyoo, Zhou, Yongdong, Zhu, Min, Petasis, Nicos A., Gordon, William C., Bazan, Nicolas G.
Publicado 2013

Membrane‐type frizzled‐related protein regulates lipidome and transcription for photoreceptor function

por Kautzmann, Marie‐Audrey I., Gordon, William C., Jun, Bokkyoo, Do, Khanh V., Matherne, Blake J., Fang, Zhide, Bazan, Nicolas G.
Publicado 2019

Elovanoids counteract oligomeric β-amyloid-induced gene expression and protect photoreceptors

por Do, Khanh V., Kautzmann, Marie-Audrey I., Jun, Bokkyoo, Gordon, William C., Nshimiyimana, Robert, Yang, Rong, Petasis, Nicos A., Bazan, Nicolas G.
Publicado 2019

Elucidating the structure and functions of Resolvin D6 isomers on nerve regeneration with a distinctive trigeminal transcriptome

por Pham, Thang L., Kakazu, Azucena H., He, Jiucheng, Nshimiyimana, Robert, Petasis, Nicos A., Jun, Bokkyoo, Bazan, Nicolas G., Bazan, Haydee E. P.
Publicado 2021

Cerebrospinal Fluid Profile of Lipid Mediators in Alzheimer’s Disease

por Do, Khanh V., Hjorth, Erik, Wang, Ying, Jun, Bokkyoo, Kautzmann, Marie-Audrey I., Ohshima, Makiko, Eriksdotter, Maria, Schultzberg, Marianne, Bazan, Nicolas G.
Publicado 2022

Increased Antioxidant Capacity and Pro-Homeostatic Lipid Mediators in Ocular Hypertension—A Human Experimental Model

por Langbøl, Mia, Saruhanian, Sarkis, Baskaran, Thisayini, Tiedemann, Daniel, Mouhammad, Zaynab A., Toft-Kehler, Anne Katrine, Jun, Bokkyoo, Vohra, Rupali, Bazan, Nicolas G., Kolko, Miriam
Publicado 2020

Elovanoids are novel cell-specific lipid mediators necessary for neuroprotective signaling for photoreceptor cell integrity

por Jun, Bokkyoo, Mukherjee, Pranab K., Asatryan, Aram, Kautzmann, Marie-Audrey, Heap, Jessica, Gordon, William C., Bhattacharjee, Surjyadipta, Yang, Rong, Petasis, Nicos A., Bazan, Nicolas G.
Publicado 2017

Age-related changes in brain phospholipids and bioactive lipids in the APP knock-in mouse model of Alzheimer’s disease

por Emre, Ceren, Do, Khanh V., Jun, Bokkyoo, Hjorth, Erik, Alcalde, Silvia Gómez, Kautzmann, Marie-Audrey I., Gordon, William C., Nilsson, Per, Bazan, Nicolas G., Schultzberg, Marianne
Publicado 2021

Elovanoids are a novel class of homeostatic lipid mediators that protect neural cell integrity upon injury

por Bhattacharjee, Surjyadipta, Jun, Bokkyoo, Belayev, Ludmila, Heap, Jessica, Kautzmann, Marie-Audrey, Obenaus, Andre, Menghani, Hemant, Marcell, Shawn J., Khoutorova, Larissa, Yang, Rong, Petasis, Nicos A., Bazan, Nicolas G.
Publicado 2017

Transcriptomic signature, bioactivity and safety of a non-hepatoxic analgesic generating AM404 in the mid-brain PAG region

por Bazan, Hernan, Bhattacharjee, Surjyadipta, Reid, Madigan, Jun, Bokkyoo, Polk, Connor, Strain, Madeleine, Pierre, Linsey St, Desai, Neehar, Daly, Patrick, Cucinello-Ragland, Jessica, Edwards, Scott, Alvarez-Builla, Julio, Cai, James, Bazan, Nicolas
Publicado 2023

Elovanoids downregulate SARS-CoV-2 cell-entry, canonical mediators and enhance protective signaling in human alveolar cells

por Calandria, Jorgelina M., Bhattacharjee, Surjyadipta, Maness, Nicholas J., Kautzmann, Marie-Audrey I., Asatryan, Aram, Gordon, William C., Do, Khanh V., Jun, Bokkyoo, Mukherjee, Pranab K., Petasis, Nicos A., Bazan, Nicolas G.
Publicado 2021

Intranasal delivery of pro-resolving lipid mediators rescues memory and gamma oscillation impairment in App(NL-G-F/NL-G-F) mice

por Emre, Ceren, Arroyo-García, Luis E., Do, Khanh V., Jun, Bokkyoo, Ohshima, Makiko, Alcalde, Silvia Gómez, Cothern, Megan L., Maioli, Silvia, Nilsson, Per, Hjorth, Erik, Fisahn, André, Bazan, Nicolas G., Schultzberg, Marianne
Publicado 2022

New Retinal Pigment Epithelial Cell Model to Unravel Neuroprotection Sensors of Neurodegeneration in Retinal Disease

por Asatryan, Aram, Calandria, Jorgelina M., Kautzmann, Marie-Audrey I., Jun, Bokkyoo, Gordon, William C., Do, Khanh V., Bhattacharjee, Surjyadipta, Pham, Thang L., Bermúdez, Vicente, Mateos, Melina Valeria, Heap, Jessica, Bazan, Nicolas G.
Publicado 2022

Enteral Arg-Gln Dipeptide Administration Increases Retinal Docosahexaenoic Acid and Neuroprotectin D1 in a Murine Model of Retinopathy of Prematurity

por Shaw, Lynn Calvin, Li Calzi, Sergio, Li, Nan, Moldovan, Leni, Sengupta-Caballero, Nilanjana, Quigley, Judith Lindsey, Ivan, Mircea, Jun, Bokkyoo, Bazan, Nicolas G., Boulton, Michael Edwin, Busik, Julia, Neu, Josef, Grant, Maria B.
Publicado 2018

Microtubule-Associated Protein 1 Light Chain 3B, (LC3B) Is Necessary to Maintain Lipid-Mediated Homeostasis in the Retinal Pigment Epithelium

por Dhingra, Anuradha, Bell, Brent A., Peachey, Neal S., Daniele, Lauren L., Reyes-Reveles, Juan, Sharp, Rachel C., Jun, Bokkyoo, Bazan, Nicolas G., Sparrow, Janet R., Kim, Hye Jin, Philp, Nancy J., Boesze-Battaglia, Kathleen
Publicado 2018

A novel pipeline of 2-(benzenesulfonamide)-N-(4-hydroxyphenyl) acetamide analgesics that lack hepatotoxicity and retain antipyresis

por Bazan, Hernan A., Bhattacharjee, Surjyadipta, Burgos, Carolina, Recio, Javier, Abet, Valentina, Pahng, Amanda R., Jun, Bokkyoo, Heap, Jessica, Ledet, Alexander J., Gordon, William C., Edwards, Scott, Paul, Dennis, Alvarez-Builla, Julio, Bazan, Nicolas G.
Publicado 2020

Peroxisomal Multifunctional Protein 2 Deficiency Perturbs Lipid Homeostasis in the Retina and Causes Visual Dysfunction in Mice

por Das, Yannick, Swinkels, Daniëlle, Kocherlakota, Sai, Vinckier, Stefan, Vaz, Frédéric M., Wever, Eric, van Kampen, Antoine H. C., Jun, Bokkyoo, Do, Khanh V., Moons, Lieve, Bazan, Nicolas G., Van Veldhoven, Paul P., Baes, Myriam
Publicado 2021