Comparison of methods for multivariate gene-based association tests for complex diseases using common variants

por Chung, Jaeyoon, Jun, Gyungah R., Dupuis, Josée, Farrer, Lindsay A.
Publicado 2019

Blood and brain transcriptome analysis reveals APOE genotype-mediated and immune-related pathways involved in Alzheimer disease

por Panitch, Rebecca, Hu, Junming, Xia, Weiming, Bennett, David A., Stein, Thor D., Farrer, Lindsay A., Jun, Gyungah R.
Publicado 2022

Cytokine Levels in Human Vitreous in Proliferative Diabetic Retinopathy

por Loporchio, Dean F., Tam, Emily K., Cho, Jane, Chung, Jaeyoon, Jun, Gyungah R., Xia, Weiming, Fiorello, Marissa G., Siegel, Nicole H., Ness, Steven, Stein, Thor D., Subramanian, Manju L.
Publicado 2021

Neurofilament light chain in the vitreous humor of the eye

por Subramanian, Manju L., Vig, Viha, Chung, Jaeyoon, Fiorello, Marissa G., Xia, Weiming, Zetterberg, Henrik, Blennow, Kaj, Zetterberg, Madeleine, Shareef, Farah, Siegel, Nicole H., Ness, Steven, Jun, Gyungah R., Stein, Thor D.
Publicado 2020

Integrative brain transcriptome analysis links complement component 4 and HSPA2 to the APOE ε2 protective effect in Alzheimer disease

por Panitch, Rebecca, Hu, Junming, Chung, Jaeyoon, Zhu, Congcong, Meng, Gaoyuan, Xia, Weiming, Bennett, David A., Lunetta, Kathryn L., Ikezu, Tsuneya, Au, Rhoda, Stein, Thor D., Farrer, Lindsay A., Jun, Gyungah R.
Publicado 2021

CpG‐related SNPs in the MS4A region have a dose‐dependent effect on risk of late–onset Alzheimer disease

por Ma, Yiyi, Jun, Gyungah R., Chung, Jaeyoon, Zhang, Xiaoling, Kunkle, Brian W., Naj, Adam C., White, Charles C., Bennett, David A, De Jager, Philip L., Mayeux, Richard, Haines, Jonathan L., Pericak‐Vance, Margaret A., Schellenberg, Gerard D., Farrer, Lindsay A., Lunetta, Kathryn L.
Publicado 2019

Protein phosphatase 2A and complement component 4 are linked to the protective effect of APOE ɛ2 for Alzheimer's disease

por Jun, Gyungah R., You, Yang, Zhu, Congcong, Meng, Gaoyuan, Chung, Jaeyoon, Panitch, Rebecca, Hu, Junming, Xia, Weiming, Bennett, David A., Foroud, Tatiana M., Wang, Li‐San, Haines, Jonathan L., Mayeux, Richard, Pericak‐Vance, Margaret A., Schellenberg, Gerard D., Au, Rhoda, Lunetta, Kathryn L., Ikezu, Tsuneya, Stein, Thor D., Farrer, Lindsay A.
Publicado 2022

Genome-wide pleiotropy analysis of neuropathological traits related to Alzheimer’s disease

por Chung, Jaeyoon, Zhang, Xiaoling, Allen, Mariet, Wang, Xue, Ma, Yiyi, Beecham, Gary, Montine, Thomas J., Younkin, Steven G., Dickson, Dennis W., Golde, Todd E., Price, Nathan D., Ertekin-Taner, Nilüfer, Lunetta, Kathryn L., Mez, Jesse, Mayeux, Richard, Haines, Jonathan L., Pericak-Vance, Margaret A., Schellenberg, Gerard, Jun, Gyungah R., Farrer, Lindsay A.
Publicado 2018

Cross‐sectional and longitudinal evaluation of plasma glial fibrillary acidic protein to detect and predict clinical syndromes of Alzheimer's disease

por Ally, Madeline, Sugarman, Michael A., Zetterberg, Henrik, Blennow, Kaj, Ashton, Nicholas J., Karikari, Thomas K., Aparicio, Hugo J., Frank, Brandon, Tripodis, Yorghos, Martin, Brett, Palmisano, Joseph N., Steinberg, Eric G., Simkin, Irene, Farrer, Lindsay A., Jun, Gyungah R., Turk, Katherine W., Budson, Andrew E., O'Connor, Maureen K., Au, Rhoda, Goldstein, Lee E., Kowall, Neil W., Killiany, Ronald, Stern, Robert A., Stein, Thor D., McKee, Ann C., Qiu, Wei Qiao, Mez, Jesse, Alosco, Michael L.
Publicado 2023

A missense variant in SHARPIN mediates Alzheimer’s disease-specific brain damages

por Park, Jun Young, Lee, Dongsoo, Lee, Jang Jae, Gim, Jungsoo, Gunasekaran, Tamil Iniyan, Choi, Kyu Yeong, Kang, Sarang, Do, Ah Ra, Jo, Jinyeon, Park, Juhong, Park, Kyungtaek, Li, Donghe, Lee, Sanghun, Kim, Hoowon, Dhanasingh, Immanuel, Ghosh, Suparna, Keum, Seula, Choi, Jee Hye, Song, Gyun Jee, Sael, Lee, Rhee, Sangmyung, Lovestone, Simon, Kim, Eunae, Moon, Seung Hwan, Kim, Byeong C., Kim, SangYun, Saykin, Andrew J., Nho, Kwangsik, Lee, Sung Haeng, Farrer, Lindsay A., Jun, Gyungah R., Won, Sungho, Lee, Kun Ho
Publicado 2021

Resistance to autosomal dominant Alzheimer’s in an APOE3-Christchurch homozygote: a case report

por Arboleda-Velasquez, Joseph F., Lopera, Francisco, O’Hare, Michael, Delgado-Tirado, Santiago, Marino, Claudia, Chmielewska, Natalia, Saez-Torres, Kahira L., Amarnani, Dhanesh, Schultz, Aaron P., Sperling, Reisa A., Leyton-Cifuentes, David, Chen, Kewei, Baena, Ana, Aguillon, David, Rios-Romenets, Silvia, Giraldo, Margarita, Guzmán-Vélez, Edmarie, Norton, Daniel J., Pardilla-Delgado, Enmanuelle, Artola, Arabiye, Sanchez, Justin S., Acosta-Uribe, Juliana, Lalli, Matthew, Kosik, Kenneth S., Huentelman, Matthew J., Zetterberg, Henrik, Blennow, Kaj, Reiman, Rebecca A., Luo, Ji, Chen, Yinghua, Thiyyagura, Pradeep, Su, Yi, Jun, Gyungah R., Naymik, Marcus, Gai, Xiaowu, Bootwalla, Moiz, Ji, Jianling, Shen, Lishuang, Miller, John B., Kim, Leo A., Tariot, Pierre N., Johnson, Keith A., Reiman, Eric M., Quiroz, Yakeel T.
Publicado 2019

Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study

por Reiman, Eric M., Arboleda-Velasquez, Joseph F., Quiroz, Yakeel T., Huentelman, Matthew J., Beach, Thomas G., Caselli, Richard J., Chen, Yinghua, Su, Yi, Myers, Amanda J., Hardy, John, Paul Vonsattel, Jean, Younkin, Steven G., Bennett, David A., De Jager, Philip L., Larson, Eric B., Crane, Paul K., Keene, C. Dirk, Kamboh, M. Ilyas, Kofler, Julia K., Duque, Linda, Gilbert, John R., Gwirtsman, Harry E., Buxbaum, Joseph D., Dickson, Dennis W., Frosch, Matthew P., Ghetti, Bernardino F., Lunetta, Kathryn L., Wang, Li-San, Hyman, Bradley T., Kukull, Walter A., Foroud, Tatiana, Haines, Jonathan L., Mayeux, Richard P., Pericak-Vance, Margaret A., Schneider, Julie A., Trojanowski, John Q., Farrer, Lindsay A., Schellenberg, Gerard D., Beecham, Gary W., Montine, Thomas J., Jun, Gyungah R.
Publicado 2020

APOE Promoter Polymorphism-219T/G is an Effect Modifier of the Influence of APOE ε4 on Alzheimer’s Disease Risk in a Multiracial Sample

por Choi, Kyu Yeong, Lee, Jang Jae, Gunasekaran, Tamil Iniyan, Kang, Sarang, Lee, Wooje, Jeong, Jangho, Lim, Ho Jae, Zhang, Xiaoling, Zhu, Congcong, Won, So-Yoon, Choi, Yu Yong, Seo, Eun Hyun, Lee, Seok Cheol, Gim, Jungsoo, Chung, Ji Yeon, Chong, Ari, Byun, Min Soo, Seo, Sujin, Ko, Pan-Woo, Han, Ji-Won, McLean, Catriona, Farrell, John, Lunetta, Kathryn L., Miyashita, Akinori, Hara, Norikazu, Won, Sungho, Choi, Seong-Min, Ha, Jung-Min, Jeong, Jee Hyang, Kuwano, Ryozo, Song, Min Kyung, An, Seong Soo A., Lee, Young Min, Park, Kyung Won, Lee, Ho-Won, Choi, Seong Hye, Rhee, Sangmyung, Song, Woo Keun, Lee, Jung Sup, Mayeux, Richard, Haines, Jonathan L., Pericak-Vance, Margaret A., Choo, IL Han, Nho, Kwangsik, Kim, Ki-Woong, Lee, Dong Young, Kim, SangYun, Kim, Byeong C., Kim, Hoowon, Jun, Gyungah R., Schellenberg, Gerard D., Ikeuchi, Takeshi, Farrer, Lindsay A., Lee, Kun Ho
Publicado 2019

Common variants in SOX-2 and congenital cataract genes contribute to age-related nuclear cataract

por Yonova-Doing, Ekaterina, Zhao, Wanting, Igo, Robert P., Wang, Chaolong, Sundaresan, Periasamy, Lee, Kristine E., Jun, Gyungah R., Alves, Alexessander Couto, Chai, Xiaoran, Chan, Anita S. Y., Lee, Mei Chin, Fong, Allan, Tan, Ava G., Khor, Chiea Chuen, Chew, Emily Y., Hysi, Pirro G., Fan, Qiao, Chua, Jacqueline, Chung, Jaeyoon, Liao, Jiemin, Colijn, Johanna M., Burdon, Kathryn P., Fritsche, Lars G., Swift, Maria K., Hilmy, Maryam H., Chee, Miao Ling, Tedja, Milly, Bonnemaijer, Pieter W. M., Gupta, Preeti, Tan, Queenie S., Li, Zheng, Vithana, Eranga N., Ravindran, Ravilla D., Chee, Soon-Phaik, Shi, Yuan, Liu, Wenting, Su, Xinyi, Sim, Xueling, Shen, Yang, Wang, Ya Xing, Li, Hengtong, Tham, Yih-Chung, Teo, Yik Ying, Aung, Tin, Small, Kerrin S., Mitchell, Paul, Jonas, Jost B., Wong, Tien Yin, Fletcher, Astrid E., Klaver, Caroline C. W., Klein, Barbara E. K., Wang, Jie Jin, Iyengar, Sudha K., Hammond, Christopher J., Cheng, Ching-Yu
Publicado 2020

New insights into the genetic etiology of Alzheimer’s disease and related dementias

por Bellenguez, Céline, Küçükali, Fahri, Jansen, Iris E., Kleineidam, Luca, Moreno-Grau, Sonia, Amin, Najaf, Naj, Adam C., Campos-Martin, Rafael, Grenier-Boley, Benjamin, Andrade, Victor, Holmans, Peter A., Boland, Anne, Damotte, Vincent, van der Lee, Sven J., Costa, Marcos R., Kuulasmaa, Teemu, Yang, Qiong, de Rojas, Itziar, Bis, Joshua C., Yaqub, Amber, Prokic, Ivana, Chapuis, Julien, Ahmad, Shahzad, Giedraitis, Vilmantas, Aarsland, Dag, Garcia-Gonzalez, Pablo, Abdelnour, Carla, Alarcón-Martín, Emilio, Alcolea, Daniel, Alegret, Montserrat, Alvarez, Ignacio, Álvarez, Victoria, Armstrong, Nicola J., Tsolaki, Anthoula, Antúnez, Carmen, Appollonio, Ildebrando, Arcaro, Marina, Archetti, Silvana, Pastor, Alfonso Arias, Arosio, Beatrice, Athanasiu, Lavinia, Bailly, Henri, Banaj, Nerisa, Baquero, Miquel, Barral, Sandra, Beiser, Alexa, Pastor, Ana Belén, Below, Jennifer E., Benchek, Penelope, Benussi, Luisa, Berr, Claudine, Besse, Céline, Bessi, Valentina, Binetti, Giuliano, Bizarro, Alessandra, Blesa, Rafael, Boada, Mercè, Boerwinkle, Eric, Borroni, Barbara, Boschi, Silvia, Bossù, Paola, Bråthen, Geir, Bressler, Jan, Bresner, Catherine, Brodaty, Henry, Brookes, Keeley J., Brusco, Luis Ignacio, Buiza-Rueda, Dolores, Bûrger, Katharina, Burholt, Vanessa, Bush, William S., Calero, Miguel, Cantwell, Laura B., Chene, Geneviève, Chung, Jaeyoon, Cuccaro, Michael L., Carracedo, Ángel, Cecchetti, Roberta, Cervera-Carles, Laura, Charbonnier, Camille, Chen, Hung-Hsin, Chillotti, Caterina, Ciccone, Simona, Claassen, Jurgen A. H. R., Clark, Christopher, Conti, Elisa, Corma-Gómez, Anaïs, Costantini, Emanuele, Custodero, Carlo, Daian, Delphine, Dalmasso, Maria Carolina, Daniele, Antonio, Dardiotis, Efthimios, Dartigues, Jean-François, de Deyn, Peter Paul, de Paiva Lopes, Katia, de Witte, Lot D., Debette, Stéphanie, Deckert, Jürgen, del Ser, Teodoro, Denning, Nicola, DeStefano, Anita, Dichgans, Martin, Diehl-Schmid, Janine, Diez-Fairen, Mónica, Rossi, Paolo Dionigi, Djurovic, Srdjan, Duron, Emmanuelle, Düzel, Emrah, Dufouil, Carole, Eiriksdottir, Gudny, Engelborghs, Sebastiaan, Escott-Price, Valentina, Espinosa, Ana, Ewers, Michael, Faber, Kelley M., Fabrizio, Tagliavini, Nielsen, Sune Fallgaard, Fardo, David W., Farotti, Lucia, Fenoglio, Chiara, Fernández-Fuertes, Marta, Ferrari, Raffaele, Ferreira, Catarina B., Ferri, Evelyn, Fin, Bertrand, Fischer, Peter, Fladby, Tormod, Fließbach, Klaus, Fongang, Bernard, Fornage, Myriam, Fortea, Juan, Foroud, Tatiana M., Fostinelli, Silvia, Fox, Nick C., Franco-Macías, Emlio, Bullido, María J., Frank-García, Ana, Froelich, Lutz, Fulton-Howard, Brian, Galimberti, Daniela, García-Alberca, Jose Maria, García-González, Pablo, Garcia-Madrona, Sebastian, Garcia-Ribas, Guillermo, Ghidoni, Roberta, Giegling, Ina, Giorgio, Giaccone, Goate, Alison M., Goldhardt, Oliver, Gomez-Fonseca, Duber, González-Pérez, Antonio, Graff, Caroline, Grande, Giulia, Green, Emma, Grimmer, Timo, Grünblatt, Edna, Grunin, Michelle, Gudnason, Vilmundur, Guetta-Baranes, Tamar, Haapasalo, Annakaisa, Hadjigeorgiou, Georgios, Haines, Jonathan L., Hamilton-Nelson, Kara L., Hampel, Harald, Hanon, Olivier, Hardy, John, Hartmann, Annette M., Hausner, Lucrezia, Harwood, Janet, Heilmann-Heimbach, Stefanie, Helisalmi, Seppo, Heneka, Michael T., Hernández, Isabel, Herrmann, Martin J., Hoffmann, Per, Holmes, Clive, Holstege, Henne, Vilas, Raquel Huerto, Hulsman, Marc, Humphrey, Jack, Biessels, Geert Jan, Jian, Xueqiu, Johansson, Charlotte, Jun, Gyungah R., Kastumata, Yuriko, Kauwe, John, Kehoe, Patrick G., Kilander, Lena, Ståhlbom, Anne Kinhult, Kivipelto, Miia, Koivisto, Anne, Kornhuber, Johannes, Kosmidis, Mary H., Kukull, Walter A., Kuksa, Pavel P., Kunkle, Brian W., Kuzma, Amanda B., Lage, Carmen, Laukka, Erika J., Launer, Lenore, Lauria, Alessandra, Lee, Chien-Yueh, Lehtisalo, Jenni, Lerch, Ondrej, Lleó, Alberto, Longstreth, William, Lopez, Oscar, de Munain, Adolfo Lopez, Love, Seth, Löwemark, Malin, Luckcuck, Lauren, Lunetta, Kathryn L., Ma, Yiyi, Macías, Juan, MacLeod, Catherine A., Maier, Wolfgang, Mangialasche, Francesca, Spallazzi, Marco, Marquié, Marta, Marshall, Rachel, Martin, Eden R., Montes, Angel Martín, Rodríguez, Carmen Martínez, Masullo, Carlo, Mayeux, Richard, Mead, Simon, Mecocci, Patrizia, Medina, Miguel, Meggy, Alun, Mehrabian, Shima, Mendoza, Silvia, Menéndez-González, Manuel, Mir, Pablo, Moebus, Susanne, Mol, Merel, Molina-Porcel, Laura, Montrreal, Laura, Morelli, Laura, Moreno, Fermin, Morgan, Kevin, Mosley, Thomas, Nöthen, Markus M., Muchnik, Carolina, Mukherjee, Shubhabrata, Nacmias, Benedetta, Ngandu, Tiia, Nicolas, Gael, Nordestgaard, Børge G., Olaso, Robert, Orellana, Adelina, Orsini, Michela, Ortega, Gemma, Padovani, Alessandro, Paolo, Caffarra, Papenberg, Goran, Parnetti, Lucilla, Pasquier, Florence, Pastor, Pau, Peloso, Gina, Pérez-Cordón, Alba, Pérez-Tur, Jordi, Pericard, Pierre, Peters, Oliver, Pijnenburg, Yolande A. L., Pineda, Juan A., Piñol-Ripoll, Gerard, Pisanu, Claudia, Polak, Thomas, Popp, Julius, Posthuma, Danielle, Priller, Josef, Puerta, Raquel, Quenez, Olivier, Quintela, Inés, Thomassen, Jesper Qvist, Rábano, Alberto, Rainero, Innocenzo, Rajabli, Farid, Ramakers, Inez, Real, Luis M., Reinders, Marcel J. T., Reitz, Christiane, Reyes-Dumeyer, Dolly, Ridge, Perry, Riedel-Heller, Steffi, Riederer, Peter, Roberto, Natalia, Rodriguez-Rodriguez, Eloy, Rongve, Arvid, Allende, Irene Rosas, Rosende-Roca, Maitée, Royo, Jose Luis, Rubino, Elisa, Rujescu, Dan, Sáez, María Eugenia, Sakka, Paraskevi, Saltvedt, Ingvild, Sanabria, Ángela, Sánchez-Arjona, María Bernal, Sanchez-Garcia, Florentino, Juan, Pascual Sánchez, Sánchez-Valle, Raquel, Sando, Sigrid B., Sarnowski, Chloé, Satizabal, Claudia L., Scamosci, Michela, Scarmeas, Nikolaos, Scarpini, Elio, Scheltens, Philip, Scherbaum, Norbert, Scherer, Martin, Schmid, Matthias, Schneider, Anja, Schott, Jonathan M., Selbæk, Geir, Seripa, Davide, Serrano, Manuel, Sha, Jin, Shadrin, Alexey A., Skrobot, Olivia, Slifer, Susan, Snijders, Gijsje J. L., Soininen, Hilkka, Solfrizzi, Vincenzo, Solomon, Alina, Song, Yeunjoo, Sorbi, Sandro, Sotolongo-Grau, Oscar, Spalletta, Gianfranco, Spottke, Annika, Squassina, Alessio, Stordal, Eystein, Tartan, Juan Pablo, Tárraga, Lluís, Tesí, Niccolo, Thalamuthu, Anbupalam, Thomas, Tegos, Tosto, Giuseppe, Traykov, Latchezar, Tremolizzo, Lucio, Tybjærg-Hansen, Anne, Uitterlinden, Andre, Ullgren, Abbe, Ulstein, Ingun, Valero, Sergi, Valladares, Otto, Broeckhoven, Christine Van, Vance, Jeffery, Vardarajan, Badri N., van der Lugt, Aad, Dongen, Jasper Van, van Rooij, Jeroen, van Swieten, John, Vandenberghe, Rik, Verhey, Frans, Vidal, Jean-Sébastien, Vogelgsang, Jonathan, Vyhnalek, Martin, Wagner, Michael, Wallon, David, Wang, Li-San, Wang, Ruiqi, Weinhold, Leonie, Wiltfang, Jens, Windle, Gill, Woods, Bob, Yannakoulia, Mary, Zare, Habil, Zhao, Yi, Zhang, Xiaoling, Zhu, Congcong, Zulaica, Miren, Farrer, Lindsay A., Psaty, Bruce M., Ghanbari, Mohsen, Raj, Towfique, Sachdev, Perminder, Mather, Karen, Jessen, Frank, Ikram, M. Arfan, de Mendonça, Alexandre, Hort, Jakub, Tsolaki, Magda, Pericak-Vance, Margaret A., Amouyel, Philippe, Williams, Julie, Frikke-Schmidt, Ruth, Clarimon, Jordi, Deleuze, Jean-François, Rossi, Giacomina, Seshadri, Sudha, Andreassen, Ole A., Ingelsson, Martin, Hiltunen, Mikko, Sleegers, Kristel, Schellenberg, Gerard D., van Duijn, Cornelia M., Sims, Rebecca, van der Flier, Wiesje M., Ruiz, Agustín, Ramirez, Alfredo, Lambert, Jean-Charles
Publicado 2022