AT-527, a Double Prodrug of a Guanosine Nucleotide Analog, Is a Potent Inhibitor of SARS-CoV-2 In Vitro and a Promising Oral Antiviral for Treatment of COVID-19

por Good, Steven S., Westover, Jonna, Jung, Kie Hoon, Zhou, Xiao-Jian, Moussa, Adel, La Colla, Paolo, Collu, Gabriella, Canard, Bruno, Sommadossi, Jean-Pierre
Publicado 2021

MP-12 virus containing the clone 13 deletion in the NSs gene prevents lethal disease when administered after Rift Valley fever virus infection in hamsters

por Gowen, Brian B., Westover, Jonna B., Sefing, Eric J., Bailey, Kevin W., Nishiyama, Shoko, Wandersee, Luci, Scharton, Dionna, Jung, Kie-Hoon, Ikegami, Tetsuro
Publicado 2015

Treatment of Late Stage Disease in a Model of Arenaviral Hemorrhagic Fever: T-705 Efficacy and Reduced Toxicity Suggests an Alternative to Ribavirin

por Gowen, Brian B., Smee, Donald F., Wong, Min-Hui, Hall, Jeffery O., Jung, Kie-Hoon, Bailey, Kevin W., Stevens, John R., Furuta, Yousuke, Morrey, John D.
Publicado 2008

Galidesivir limits Rift Valley fever virus infection and disease in Syrian golden hamsters

por Westover, Jonna B., Mathis, Amanda, Taylor, Ray, Wandersee, Luci, Bailey, Kevin W., Sefing, Eric J., Hickerson, Brady T., Jung, Kie-Hoon, Sheridan, William P., Gowen, Brian B.
Publicado 2018

Is the anti-psychotic, 10-(3-(dimethylamino)propyl)phenothiazine (promazine), a potential drug with which to treat SARS infections?: Lack of efficacy of promazine on SARS-CoV repli...

por Barnard, Dale L., Day, Craig W., Bailey, Kevin, Heiner, Matthew, Montgomery, Robert, Lauridsen, Larry, Jung, Kie-Hoon, Li, Joseph K.-K., Chan, Paul K.S., Sidwell, Robert W.
Publicado 2008

Development of a New Tacaribe Arenavirus Infection Model and Its Use to Explore Antiviral Activity of a Novel Aristeromycin Analog

por Gowen, Brian B., Wong, Min-Hui, Larson, Deanna, Ye, Wei, Jung, Kie-Hoon, Sefing, Eric J., Skirpstunas, Ramona, Smee, Donald F., Morrey, John D., Schneller, Stewart W.
Publicado 2010

Clinical stage molecule PT150 is a modulator of glucocorticoid and androgen receptors with antiviral activity against SARS-CoV-2.

por Theise, Neil D., Arment, Anthony R., Chakravarty, Dimple, Gregg, John M. H., Jacobson, Ira M., Jung, Kie Hoon, Nair, Sujit S., Tewari, Ashutosh K., Thurston, Archie W., Van Drie, John, Westover, Jonna B.
Publicado 2020

A potent Lassa virus antiviral targets an arenavirus virulence determinant

por Madu, Ikenna G., Files, Megan, Gharaibeh, Dima N., Moore, Amy L., Jung, Kie-Hoon, Gowen, Brian B., Dai, Dongcheng, Jones, Kevin F., Tyavanagimatt, Shanthakumar R., Burgeson, James R., Korth, Marcus J., Bedard, Kristin M., Iadonato, Shawn P., Amberg, Sean M.
Publicado 2018