Allosteric control of mammalian DNA methyltransferases – a new regulatory paradigm

por Jeltsch, Albert, Jurkowska, Renata Z.
Publicado 2016

Function and disruption of DNA Methyltransferase 3a cooperative DNA binding and nucleoprotein filament formation

por Rajavelu, Arumugam, Jurkowska, Renata Z., Fritz, Jürgen, Jeltsch, Albert
Publicado 2012

The DNMT3A R882H mutation does not cause dominant negative effects in purified mixed DNMT3A/R882H complexes

por Emperle, Max, Dukatz, Michael, Kunert, Stefan, Holzer, Katharina, Rajavelu, Arumugam, Jurkowska, Renata Z., Jeltsch, Albert
Publicado 2018

The DNMT3A R882H mutant displays altered flanking sequence preferences

por Emperle, Max, Rajavelu, Arumugam, Kunert, Stefan, Arimondo, Paola B, Reinhardt, Richard, Jurkowska, Renata Z, Jeltsch, Albert
Publicado 2018

Formation of nucleoprotein filaments by mammalian DNA methyltransferase Dnmt3a in complex with regulator Dnmt3L

por Jurkowska, Renata Z., Anspach, Nils, Urbanke, Claus, Jia, Da, Reinhardt, Richard, Nellen, Wolfgang, Cheng, Xiaodong, Jeltsch, Albert
Publicado 2008

Early Career Members at the ERS Lung Science Conference 2020: metabolic alterations in lung ageing and disease

por Ogger, Patricia P., Silva, Johnatas Dutra, Aghapour, Mahyar, Mahmutovic Persson, Irma, Tulen, Christy, Jurkowska, Renata, Ubags, Niki D.
Publicado 2020

Application of histone modification-specific interaction domains as an alternative to antibodies

por Kungulovski, Goran, Kycia, Ina, Tamas, Raluca, Jurkowska, Renata Z., Kudithipudi, Srikanth, Henry, Chisato, Reinhardt, Richard, Labhart, Paul, Jeltsch, Albert
Publicado 2014

Efficient targeted DNA methylation with chimeric dCas9–Dnmt3a–Dnmt3L methyltransferase

por Stepper, Peter, Kungulovski, Goran, Jurkowska, Renata Z., Chandra, Tamir, Krueger, Felix, Reinhardt, Richard, Reik, Wolf, Jeltsch, Albert, Jurkowski, Tomasz P.
Publicado 2017

Chromatin methylation activity of Dnmt3a and Dnmt3a/3L is guided by interaction of the ADD domain with the histone H3 tail

por Zhang, Yingying, Jurkowska, Renata, Soeroes, Szabolcs, Rajavelu, Arumugam, Dhayalan, Arunkumar, Bock, Ina, Rathert, Philipp, Brandt, Ole, Reinhardt, Richard, Fischle, Wolfgang, Jeltsch, Albert
Publicado 2010

Mechanistic Insights on the Inhibition of C5 DNA Methyltransferases by Zebularine

por Champion, Christine, Guianvarc'h, Dominique, Sénamaud-Beaufort, Catherine, Jurkowska, Renata Z., Jeltsch, Albert, Ponger, Loïc, Arimondo, Paola B., Guieysse-Peugeot, Anne-Laure
Publicado 2010

Chromatin-dependent allosteric regulation of DNMT3A activity by MeCP2

por Rajavelu, Arumugam, Lungu, Cristiana, Emperle, Max, Dukatz, Michael, Bröhm, Alexander, Broche, Julian, Hanelt, Ines, Parsa, Edris, Schiffers, Sarah, Karnik, Rahul, Meissner, Alexander, Carell, Thomas, Rathert, Philipp, Jurkowska, Renata Z, Jeltsch, Albert
Publicado 2018

EpiCRISPR targeted methylation of Arx gene initiates transient switch of mouse pancreatic alpha to insulin-producing cells

por Đorđević, Marija, Stepper, Peter, Feuerstein-Akgoz, Clarissa, Gerhauser, Clarissa, Paunović, Verica, Tolić, Anja, Rajić, Jovana, Dinić, Svetlana, Uskoković, Aleksandra, Grdović, Nevena, Mihailović, Mirjana, Jurkowska, Renata Z., Jurkowski, Tomasz P., Jovanović, Jelena Arambašić, Vidaković, Melita
Publicado 2023

A solid‐phase transfection platform for arrayed CRISPR screens

por Serçin, Özdemirhan, Reither, Sabine, Roidos, Paris, Ballin, Nadja, Palikyras, Spyridon, Baginska, Anna, Rein, Katrin, Llamazares, Maria, Halavatyi, Aliaksandr, Winter, Hauke, Muley, Thomas, Jurkowska, Renata Z, Abdollahi, Amir, Zenke, Frank T, Neumann, Beate, Mardin, Balca R
Publicado 2019

H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1

por Jurkowska, Renata Z., Qin, Su, Kungulovski, Goran, Tempel, Wolfram, Liu, Yanli, Bashtrykov, Pavel, Stiefelmaier, Judith, Jurkowski, Tomasz P., Kudithipudi, Srikanth, Weirich, Sara, Tamas, Raluca, Wu, Hong, Dombrovski, Ludmila, Loppnau, Peter, Reinhardt, Richard, Min, Jinrong, Jeltsch, Albert
Publicado 2017

Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms

por Gao, Linfeng, Emperle, Max, Guo, Yiran, Grimm, Sara A., Ren, Wendan, Adam, Sabrina, Uryu, Hidetaka, Zhang, Zhi-Min, Chen, Dongliang, Yin, Jiekai, Dukatz, Michael, Anteneh, Hiwot, Jurkowska, Renata Z., Lu, Jiuwei, Wang, Yinsheng, Bashtrykov, Pavel, Wade, Paul A., Wang, Gang Greg, Jeltsch, Albert, Song, Jikui
Publicado 2020

Pronounced sequence specificity of the TET enzyme catalytic domain guides its cellular function

por Ravichandran, Mirunalini, Rafalski, Dominik, Davies, Claudia I., Ortega-Recalde, Oscar, Nan, Xinsheng, Glanfield, Cassandra R., Kotter, Annika, Misztal, Katarzyna, Wang, Andrew H., Wojciechowski, Marek, Rażew, Michał, Mayyas, Issam M., Kardailsky, Olga, Schwartz, Uwe, Zembrzycki, Krzysztof, Morison, Ian M., Helm, Mark, Weichenhan, Dieter, Jurkowska, Renata Z., Krueger, Felix, Plass, Christoph, Zacharias, Martin, Bochtler, Matthias, Hore, Timothy A., Jurkowski, Tomasz P.
Publicado 2022

Versatile workflow for cell type–resolved transcriptional and epigenetic profiles from cryopreserved human lung

por Llamazares-Prada, Maria, Espinet, Elisa, Mijošek, Vedrana, Schwartz, Uwe, Lutsik, Pavlo, Tamas, Raluca, Richter, Mandy, Behrendt, Annika, Pohl, Stephanie T., Benz, Naja P., Muley, Thomas, Warth, Arne, Heußel, Claus Peter, Winter, Hauke, Landry, Jonathan J. M., Herth, Felix J.F., Mertens, Tinne C.J., Karmouty-Quintana, Harry, Koch, Ina, Benes, Vladimir, Korbel, Jan O., Waszak, Sebastian M., Trumpp, Andreas, Wyatt, David M., Stahl, Heiko F., Plass, Christoph, Jurkowska, Renata Z.
Publicado 2021

High‐resolution transcriptomic and epigenetic profiling identifies novel regulators of COPD

por Schwartz, Uwe, Llamazares Prada, Maria, Pohl, Stephanie T, Richter, Mandy, Tamas, Raluca, Schuler, Michael, Keller, Corinna, Mijosek, Vedrana, Muley, Thomas, Schneider, Marc A, Quast, Karsten, Hey, Joschka, Heußel, Claus P, Warth, Arne, Winter, Hauke, Serçin, Özdemirhan, Karmouty‐Quintana, Harry, Jyothula, Soma SK, Patel, Manish K, Herth, Felix, Koch, Ina, Petrosino, Giuseppe, Titimeaua, Alexandru, Mardin, Balca R, Weichenhan, Dieter, Jurkowski, Tomasz P, Imbusch, Charles D, Brors, Benedikt, Benes, Vladimir, Jung, Birgit, Wyatt, David, Stahl, Heiko F, Plass, Christoph, Jurkowska, Renata Z
Publicado 2023