Farnesyltransferase inhibitor LNK-754 attenuates axonal dystrophy and reduces amyloid pathology in mice

por Cuddy, Leah K., Alia, Alia O., Salvo, Miranda A., Chandra, Sidhanth, Grammatopoulos, Tom N., Justman, Craig J., Lansbury, Peter T., Mazzulli, Joseph R., Vassar, Robert
Publicado 2022

A randomized single and multiple ascending dose study in healthy volunteers of LTI‐291, a centrally penetrant glucocerebrosidase activator

por den Heijer, Jonas M., Kruithof, Annelieke C., van Amerongen, Guido, de Kam, Marieke L., Thijssen, Eva, Grievink, Hendrika W., Moerland, Matthijs, Walker, Mike, Been, Kees, Skerlj, Renato, Justman, Craig, Dudgeon, Lindsay, Lansbury, Peter, Cullen, Valerie C., Hilt, Dana C., Groeneveld, Geert Jan
Publicado 2021