Coumarin-Based Profluorescent and Fluorescent Substrates for Determining Xenobiotic-Metabolizing Enzyme Activities In Vitro

por Raunio, Hannu, Pentikäinen, Olli, Juvonen, Risto O.
Publicado 2020

Modeling of interactions between xenobiotics and cytochrome P450 (CYP) enzymes

por Raunio, Hannu, Kuusisto, Mira, Juvonen, Risto O., Pentikäinen, Olli T.
Publicado 2015

Western Diet Decreases Hepatic Drug Metabolism in Male LDLr(−/−)ApoB(100/100) Mice

por Koponen, Markus, Rysä, Jaana, Ruotsalainen, Anna-Kaisa, Kärkkäinen, Olli, Juvonen, Risto O.
Publicado 2023

Apoptosis-induced anticancer effect of transferrin-conjugated solid lipid nanoparticles of curcumin

por Mulik, Rohit S., Mönkkönen, Jukka, Juvonen, Risto O., Mahadik, Kakasaheb R., Paradkar, Anant R.
Publicado 2012

Comparison of trapping profiles between d-peptides and glutathione in the identification of reactive metabolites

por Laine, Jaana E., Häkkinen, Merja R., Auriola, Seppo, Juvonen, Risto O., Pasanen, Markku
Publicado 2015

In Vitro Human Metabolism and Inhibition Potency of Verbascoside for CYP Enzymes

por Reid, Anna-Mari, Juvonen, Risto, Huuskonen, Pasi, Lehtonen, Marko, Pasanen, Markku, Lall, Namrita
Publicado 2019

Substrate Selectivity of Coumarin Derivatives by Human CYP1 Enzymes: In Vitro Enzyme Kinetics and In Silico Modeling

por Juvonen, Risto O., Ahinko, Mira, Jokinen, Elmeri M., Huuskonen, Juhani, Raunio, Hannu, Pentikäinen, Olli T.
Publicado 2021

Reduced natriuretic response to acute sodium loading in COMT Gene deleted mice

por Odlind, Cecilia, Reenilä, Ilkka, Männistö, Pekka T, Juvonen, Risto, Uhlén, Staffan, Gogos, Joseph A, Karayiorgou, Maria, Hansell, Peter
Publicado 2002

Molecular Docking-Based Design and Development of a Highly Selective Probe Substrate for UDP-glucuronosyltransferase 1A10

por Juvonen, Risto O., Rauhamäki, Sanna, Kortet, Sami, Niinivehmas, Sanna, Troberg, Johanna, Petsalo, Aleksanteri, Huuskonen, Juhani, Raunio, Hannu, Finel, Moshe, Pentikäinen, Olli T.
Publicado 2018

Identification of Gut Microbial Lysine and Histidine Degradation and CYP-Dependent Metabolites as Biomarkers of Fatty Liver Disease

por Driuchina, Anastasiia, Hintikka, Jukka, Lehtonen, Marko, Keski-Rahkonen, Pekka, O’Connell, Thomas, Juvonen, Risto, Kuula, Juho, Hakkarainen, Antti, Laukkanen, Jari A., Mäkinen, Elina, Lensu, Sanna, Pietiläinen, Kirsi H., Pekkala, Satu
Publicado 2023

Blocking oestradiol synthesis pathways with potent and selective coumarin derivatives

por Niinivehmas, Sanna, Postila, Pekka A., Rauhamäki, Sanna, Manivannan, Elangovan, Kortet, Sami, Ahinko, Mira, Huuskonen, Pasi, Nyberg, Niina, Koskimies, Pasi, Lätti, Sakari, Multamäki, Elina, Juvonen, Risto O., Raunio, Hannu, Pasanen, Markku, Huuskonen, Juhani, Pentikäinen, Olli T.
Publicado 2018

Structure-Activity Relationship Analysis of 3-Phenylcoumarin-Based Monoamine Oxidase B Inhibitors

por Rauhamäki, Sanna, Postila, Pekka A., Niinivehmas, Sanna, Kortet, Sami, Schildt, Emmi, Pasanen, Mira, Manivannan, Elangovan, Ahinko, Mira, Koskimies, Pasi, Nyberg, Niina, Huuskonen, Pasi, Multamäki, Elina, Pasanen, Markku, Juvonen, Risto O., Raunio, Hannu, Huuskonen, Juhani, Pentikäinen, Olli T.
Publicado 2018

A Comprehensive Evaluation of Sdox, a Promising H(2)S-Releasing Doxorubicin for the Treatment of Chemoresistant Tumors

por Alov, Petko, Al Sharif, Merilin, Aluani, Denitsa, Chegaev, Konstantin, Dinic, Jelena, Divac Rankov, Aleksandra, Fernandes, Miguel X., Fusi, Fabio, García-Sosa, Alfonso T., Juvonen, Risto, Kondeva-Burdina, Magdalena, Padrón, José M., Pajeva, Ilza, Pencheva, Tania, Puerta, Adrián, Raunio, Hannu, Riganti, Chiara, Tsakovska, Ivanka, Tzankova, Virginia, Yordanov, Yordan, Saponara, Simona
Publicado 2022