Chloride sensing by WNK1 regulates NLRP3 inflammasome activation and pyroptosis

por Mayes-Hopfinger, Lindsey, Enache, Aura, Xie, Jian, Huang, Chou-Long, Köchl, Robert, Tybulewicz, Victor L. J., Fernandes-Alnemri, Teresa, Alnemri, Emad S.
Publicado 2021

Critical role of WNK1 in MYC-dependent early mouse thymocyte development

por Köchl, Robert, Vanes, Lesley, Llorian Sopena, Miriam, Chakravarty, Probir, Hartweger, Harald, Fountain, Kathryn, White, Andrea, Cowan, Jennifer, Anderson, Graham, Tybulewicz, Victor LJ
Publicado 2020

Mechanism and function of Vav1 localisation in TCR signalling

por Ksionda, Olga, Saveliev, Alexander, Köchl, Robert, Rapley, Jonathan, Faroudi, Mustapha, Smith-Garvin, Jennifer E., Wülfing, Christoph, Rittinger, Katrin, Carter, Tom, Tybulewicz, Victor L. J.
Publicado 2012

WNK1 kinase balances T cell adhesion versus migration in vivo

por Köchl, Robert, Thelen, Flavian, Vanes, Lesley, Brazao, Tiago F., Fountain, Kathryn, Xie, Jian, Huang, Chou-Long, Lyck, Ruth, Stein, Jens V., Tybulewicz, Victor L. J.
Publicado 2016

Nox2-deficient Tregs improve heart transplant outcomes via their increased graft recruitment and enhanced potency

por Trevelin, Silvia C., Zampetaki, Anna, Sawyer, Greta, Ivetic, Aleksandar, Brewer, Alison C., Smyth, Lesley Ann, Marelli-Berg, Federica, Köchl, Robert, Lechler, Robert I., Shah, Ajay M., Lombardi, Giovanna
Publicado 2021

B cell–intrinsic requirement for WNK1 kinase in antibody responses in mice

por Hayward, Darryl A., Vanes, Lesley, Wissmann, Stefanie, Sivapatham, Sujana, Hartweger, Harald, O’May, Joshua Biggs, de Boer, Leonard L., Mitter, Richard, Köchl, Robert, Stein, Jens V., Tybulewicz, Victor L.J.
Publicado 2023

Nance-Horan Syndrome-like 1 protein negatively regulates Scar/WAVE-Arp2/3 activity and inhibits lamellipodia stability and cell migration

por Law, Ah-Lai, Jalal, Shamsinar, Pallett, Tommy, Mosis, Fuad, Guni, Ahmad, Brayford, Simon, Yolland, Lawrence, Marcotti, Stefania, Levitt, James A., Poland, Simon P., Rowe-Sampson, Maia, Jandke, Anett, Köchl, Robert, Pula, Giordano, Ameer-Beg, Simon M., Stramer, Brian Marc, Krause, Matthias
Publicado 2021