Ketogenic diets attenuate cyclooxygenase and lipoxygenase gene expression in multiple sclerosis

por Bock, Markus, Karber, Mirjam, Kuhn, Hartmut
Publicado 2018

Expression Silencing of Glutathione Peroxidase 4 in Mouse Erythroleukemia Cells Delays In Vitro Erythropoiesis

por Rademacher, Marlena, Kuhn, Hartmut, Borchert, Astrid
Publicado 2021

Functional Characterization of Novel Bony Fish Lipoxygenase Isoforms and Their Possible Involvement in Inflammation

por Roigas, Sophie, Heydeck, Dagmar, Kuhn, Hartmut
Publicado 2022

Functional characterization of a novel arachidonic acid 12S‐lipoxygenase in the halotolerant bacterium Myxococcus fulvus exhibiting complex social living patterns

por Goloshchapova, Kateryna, Stehling, Sabine, Heydeck, Dagmar, Blum, Maximilian, Kuhn, Hartmut
Publicado 2018

Bony Fish Arachidonic Acid 15-Lipoxygenases Exhibit Different Catalytic Properties than Their Mammalian Orthologs, Suggesting Functional Enzyme Evolution during Vertebrate Developm...

por Roigas, Sophie, Kakularam, Kumar R., Rothe, Michael, Heydeck, Dagmar, Aparoy, Polamarasetty, Kuhn, Hartmut
Publicado 2023

Functional characterization of genetic enzyme variations in human lipoxygenases()

por Horn, Thomas, Reddy Kakularam, Kumar, Anton, Monika, Richter, Constanze, Reddanna, Pallu, Kuhn, Hartmut
Publicado 2013

Male guanine-rich RNA sequence binding factor 1 knockout mice (Grsf1(−/−)) gain less body weight during adolescence and adulthood

por Dumoulin, Bernhard, Heydeck, Dagmar, Jähn, Desiree, Lassé, Moritz, Sofi, Sajad, Ufer, Christoph, Kuhn, Hartmut
Publicado 2022

Functional Characterization of Transgenic Mice Overexpressing Human 15-Lipoxygenase-1 (ALOX15) under the Control of the aP2 Promoter

por Heydeck, Dagmar, Ufer, Christoph, Kakularam, Kumar R., Rothe, Michael, Liehr, Thomas, Poulain, Philippe, Kuhn, Hartmut
Publicado 2023

Transgenic mice overexpressing human ALOX15 under the control of the aP2 promoter are partly protected in the complete Freund’s adjuvant-induced paw inflammation model

por Heydeck, Dagmar, Kakularam, Kumar R., Labuz, Dominika, Machelska, Halina, Rohwer, Nadine, Weylandt, Karsten, Kuhn, Hartmut
Publicado 2023

Functional Characterization of Mouse and Human Arachidonic Acid Lipoxygenase 15B (ALOX15B) Orthologs and of Their Mutants Exhibiting Humanized and Murinized Reaction Specificities

por Kakularam, Kumar R., Canyelles-Niño, Miquel, Chen, Xin, Lluch, José M., González-Lafont, Àngels, Kuhn, Hartmut
Publicado 2023

Specific oxygenation of plasma membrane phospholipids by Pseudomonas aeruginosa lipoxygenase induces structural and functional alterations in mammalian cells

por Aldrovandi, Maceler, Banthiya, Swathi, Meckelmann, Sven, Zhou, You, Heydeck, Dagmar, O'Donnell, Valerie B., Kuhn, Hartmut
Publicado 2018

Corrigendum to “Specific oxygenation of plasma membrane phospholipids by Pseudomonas aeruginosa lipoxygenase induces structural and functional alterations in mammalian cells” [BBA-...

por Aldrovandi, Maceler, Banthiya, Swathi, Meckelmann, Sven, Zhou, You, Heydeck, Dagmar, O'Donnell, Valerie B., Kuhn, Hartmut
Publicado 2020

Knock-in mice expressing a humanized arachidonic acid 15-lipoxygenase (Alox15) carry a partly dysfunctional erythropoietic system

por Reisch, Florian, Heydeck, Dagmar, Schäfer, Marjann, Rothe, Michael, Yang, Jiaxing, Stehling, Sabine, Püschel, Gerhard P., Kuhn, Hartmut
Publicado 2023

Different Structures—Similar Effect: Do Substituted 5-(4-Methoxyphenyl)-1H-indoles and 5-(4-Methoxyphenyl)-1H-imidazoles Represent a Common Pharmacophore for Substrate Selective In...

por Zhuravlev, Alexander, Cruz, Alejandro, Aksenov, Vladislav, Golovanov, Alexey, Lluch, José M., Kuhn, Hartmut, González-Lafont, Àngels, Ivanov, Igor
Publicado 2023

Male Knock-in Mice Expressing an Arachidonic Acid Lipoxygenase 15B (Alox15B) with Humanized Reaction Specificity Are Prematurely Growth Arrested When Aging

por Schäfer, Marjann, Kakularam, Kumar R., Reisch, Florian, Rothe, Michael, Stehling, Sabine, Heydeck, Dagmar, Püschel, Gerhard P., Kuhn, Hartmut
Publicado 2022

Humanization of the Reaction Specificity of Mouse Alox15b Inversely Modified the Susceptibility of Corresponding Knock-In Mice in Two Different Animal Inflammation Models

por Schäfer, Marjann, Reisch, Florian, Labuz, Dominika, Machelska, Halina, Stehling, Sabine, Püschel, Gerhard P., Rothe, Michael, Heydeck, Dagmar, Kuhn, Hartmut
Publicado 2023

Evolutionary aspects of lipoxygenases and genetic diversity of human leukotriene signaling

por Horn, Thomas, Adel, Susan, Schumann, Ralf, Sur, Saubashya, Kakularam, Kumar Reddy, Polamarasetty, Aparoy, Redanna, Pallu, Kuhn, Hartmut, Heydeck, Dagmar
Publicado 2015

The Reaction Specificity of Mammalian ALOX15 Orthologs is Changed During Late Primate Evolution and These Alterations Might Offer Evolutionary Advantages for Hominidae

por Heydeck, Dagmar, Reisch, Florian, Schäfer, Marjann, Kakularam, Kumar R., Roigas, Sophie A., Stehling, Sabine, Püschel, Gerhard P., Kuhn, Hartmut
Publicado 2022

Unbalanced Expression of Glutathione Peroxidase 4 and Arachidonate 15-Lipoxygenase Affects Acrosome Reaction and In Vitro Fertilization

por Soria-Tiedemann, Mariana, Michel, Geert, Urban, Iris, Aldrovandi, Maceler, O’Donnell, Valerie B., Stehling, Sabine, Kuhn, Hartmut, Borchert, Astrid
Publicado 2022

Conformational Heterogeneity and Cooperative Effects of Mammalian ALOX15

por Ivanov, Igor, Cruz, Alejandro, Zhuravlev, Alexander, Di Venere, Almerinda, Nicolai, Eleonora, Stehling, Sabine, Lluch, José M., González-Lafont, Àngels, Kuhn, Hartmut
Publicado 2021