Pop in, pop out: a novel gene-targeting strategy for use with CRISPR-Cas9

por Kühn, Ralf, Chu, Van Trung
Publicado 2015

Conditional brain-specific knockdown of MAPK using Cre/loxP regulated RNA interference

por Hitz, Christiane, Wurst, Wolfgang, Kühn, Ralf
Publicado 2007

Local Knockdown of ERK2 in the Adult Mouse Brain Via Adeno-Associated Virus-Mediated RNA Interference

por Benedetto, Barbara Di, Wefers, Benedikt, Wurst, Wolfgang, Kühn, Ralf
Publicado 2008

Local Knockdown of ERK2 in the Adult Mouse Brain Via Adeno-Associated Virus-Mediated RNA Interference

por Di Benedetto, Barbara, Wefers, Benedikt, Wurst, Wolfgang, Kühn, Ralf
Publicado 2008

Enhancement of CRISPR-Cas9 induced precise gene editing by targeting histone H2A-K15 ubiquitination

por Bashir, Sanum, Dang, Tu, Rossius, Jana, Wolf, Johanna, Kühn, Ralf
Publicado 2020

A homology independent sequence replacement strategy in human cells using a CRISPR nuclease

por Danner, Eric, Lebedin, Mikhail, de la Rosa, Kathrin, Kühn, Ralf
Publicado 2021

Creation of targeted genomic deletions using TALEN or CRISPR/Cas nuclease pairs in one-cell mouse embryos

por Brandl, Christina, Ortiz, Oskar, Röttig, Bernhard, Wefers, Benedikt, Wurst, Wolfgang, Kühn, Ralf
Publicado 2014

Generation of a NES-mScarlet Red Fluorescent Reporter Human iPSC Line for Live Cell Imaging and Flow Cytometric Analysis and Sorting Using CRISPR-Cas9-Mediated Gene Editing

por Nouri, Parivash, Zimmer, Anja, Brüggemann, Stefanie, Friedrich, Robin, Kühn, Ralf, Prakash, Nilima
Publicado 2022

Application of a Spacer-nick Gene-targeting Approach to Repair Disease-causing Mutations with Increased Safety

por Tran, Ngoc Tung, Lebedin, Mikhail, Danner, Eric, Kühn, Ralf, Rajewsky, Klaus, Chu, Van Trung
Publicado 2023

An RNAi-Based Approach to Down-Regulate a Gene Family In Vivo

por Kim, Jeehee, Badaloni, Aurora, Willert, Torsten, Zimber-Strobl, Ursula, Kühn, Ralf, Wurst, Wolfgang, Kieslinger, Matthias
Publicado 2013

Correction: An RNAi-Based Approach to Down-Regulate a Gene Family In Vivo

por Kim, Jeehee, Badaloni, Aurora, Willert, Torsten, Zimber-Strobl, Ursula, Kühn, Ralf, Wurst, Wolfgang, Kieslinger, Matthias
Publicado 2013

A deletion containing a CTCF-element in intron 8 of the Bbs7 gene is partially responsible for juvenile obesity in the Berlin Fat Mouse

por Krause, Florian, Mohebian, Kourosh, Delpero, Manuel, Hesse, Deike, Kühn, Ralf, Arends, Danny, Brockmann, Gudrun A.
Publicado 2021

Development of an intein-mediated split–Cas9 system for gene therapy

por Truong, Dong-Jiunn Jeffery, Kühner, Karin, Kühn, Ralf, Werfel, Stanislas, Engelhardt, Stefan, Wurst, Wolfgang, Ortiz, Oskar
Publicado 2015

Enhancement of Precise Gene Editing by the Association of Cas9 With Homologous Recombination Factors

por Tran, Ngoc-Tung, Bashir, Sanum, Li, Xun, Rossius, Jana, Chu, Van Trung, Rajewsky, Klaus, Kühn, Ralf
Publicado 2019

Corrigendum: Enhancement of Precise Gene Editing by the Association of Cas9 With Homologous Recombination Factors

por Tran, Ngoc-Tung, Bashir, Sanum, Li, Xun, Rossius, Jana, Chu, Van Trung, Rajewsky, Klaus, Kühn, Ralf
Publicado 2020

Development of a species-specific RNA polymerase I-based shRNA expression vector

por Verca, M. S. Brenz, Weber, Peter, Mayer, Christine, Graf, Cornelia, Refojo, Damián, Kühn, Ralf, Grummt, Ingrid, Lutz, Beat
Publicado 2007

Efficient generation of Rosa26 knock-in mice using CRISPR/Cas9 in C57BL/6 zygotes

por Chu, Van Trung, Weber, Timm, Graf, Robin, Sommermann, Thomas, Petsch, Kerstin, Sack, Ulrike, Volchkov, Pavel, Rajewsky, Klaus, Kühn, Ralf
Publicado 2016

Single copy shRNA configuration for ubiquitous gene knockdown in mice

por Seibler, Jost, Küter-Luks, Birgit, Kern, Heidrun, Streu, Sandra, Plum, Leona, Mauer, Jan, Kühn, Ralf, Brüning, Jens C., Schwenk, Frieder
Publicado 2005

Efficient CRISPR/Cas9-Mediated Gene Knockin in Mouse Hematopoietic Stem and Progenitor Cells

por Tran, Ngoc Tung, Sommermann, Thomas, Graf, Robin, Trombke, Janine, Pempe, Jenniffer, Petsch, Kerstin, Kühn, Ralf, Rajewsky, Klaus, Chu, Van Trung
Publicado 2019

CRISPR-Cas9-Mediated ELANE Mutation Correction in Hematopoietic Stem and Progenitor Cells to Treat Severe Congenital Neutropenia

por Tran, Ngoc Tung, Graf, Robin, Wulf-Goldenberg, Annika, Stecklum, Maria, Strauß, Gabriele, Kühn, Ralf, Kocks, Christine, Rajewsky, Klaus, Chu, Van Trung
Publicado 2020