CD244 expression represents functional decline of murine hematopoietic stem cells after in vitro culture

por Koide, Shuhei, Sigurdsson, Valgardur, Radulovic, Visnja, Saito, Kiyoka, Zheng, Zhiqian, Lang, Stefan, Soneji, Shamit, Iwama, Atsushi, Miharada, Kenichi
Publicado 2021

Drug resistance originating from a TGF-β/FGF-2-driven epithelial-to-mesenchymal transition and its reversion in human lung adenocarcinoma cell lines harboring an EGFR mutation

por KURIMOTO, RYOTA, IWASAWA, SHUNICHIRO, EBATA, TAKAHIRO, ISHIWATA, TSUKASA, SEKINE, IKUO, TADA, YUJI, TATSUMI, KOICHIRO, KOIDE, SHUHEI, IWAMA, ATSUSHI, TAKIGUCHI, YUICHI
Publicado 2016

Mesenchymal loss of p53 alters stem cell capacity and models human soft tissue sarcoma traits

por Sorimachi, Yuriko, Kobayashi, Hiroshi, Shiozawa, Yusuke, Koide, Shuhei, Nakato, Ryuichiro, Shimizu, Yukiko, Okamura, Tadashi, Shirahige, Katsuhiko, Iwama, Atsushi, Goda, Nobuhito, Takubo, Kaiyo, Takubo, Keiyo
Publicado 2023

Limited rejuvenation of aged hematopoietic stem cells in young bone marrow niche

por Kuribayashi, Wakako, Oshima, Motohiko, Itokawa, Naoki, Koide, Shuhei, Nakajima-Takagi, Yaeko, Yamashita, Masayuki, Yamazaki, Satoshi, Rahmutulla, Bahityar, Miura, Fumihito, Ito, Takashi, Kaneda, Atsushi, Iwama, Atsushi
Publicado 2020

Epigenetic traits inscribed in chromatin accessibility in aged hematopoietic stem cells

por Itokawa, Naoki, Oshima, Motohiko, Koide, Shuhei, Takayama, Naoya, Kuribayashi, Wakako, Nakajima-Takagi, Yaeko, Aoyama, Kazumasa, Yamazaki, Satoshi, Yamaguchi, Kiyoshi, Furukawa, Yoichi, Eto, Koji, Iwama, Atsushi
Publicado 2022

Ezh1 Targets Bivalent Genes to Maintain Self-Renewing Stem Cells in Ezh2-Insufficient Myelodysplastic Syndrome

por Aoyama, Kazumasa, Oshima, Motohiko, Koide, Shuhei, Suzuki, Emi, Mochizuki-Kashio, Makiko, Kato, Yuko, Tara, Shiro, Shinoda, Daisuke, Hiura, Nobuhiro, Nakajima-Takagi, Yaeko, Sashida, Goro, Iwama, Atsushi
Publicado 2018

Akt inhibition synergizes with polycomb repressive complex 2 inhibition in the treatment of multiple myeloma

por Rizk, Mohamed, Rizq, Ola, Oshima, Motohiko, Nakajima‐Takagi, Yaeko, Koide, Shuhei, Saraya, Atsunori, Isshiki, Yusuke, Chiba, Tetsuhiro, Yamazaki, Satoshi, Ma, Anqi, Jin, Jian, Iwama, Atsushi, Mimura, Naoya
Publicado 2019

The TIF1β-HP1 System Maintains Transcriptional Integrity of Hematopoietic Stem Cells

por Miyagi, Satoru, Koide, Shuhei, Saraya, Atsunori, Wendt, George R., Oshima, Motohiko, Konuma, Takaaki, Yamazaki, Satoshi, Mochizuki-Kashio, Makiko, Nakajima-Takagi, Yaeko, Wang, Changshan, Chiba, Tetsuhiro, Kitabayashi, Issay, Nakauchi, Hiromitsu, Iwama, Atsushi
Publicado 2014

Internal deletion of BCOR reveals a tumor suppressor function for BCOR in T lymphocyte malignancies

por Tanaka, Tomoyuki, Nakajima-Takagi, Yaeko, Aoyama, Kazumasa, Tara, Shiro, Oshima, Motohiko, Saraya, Atsunori, Koide, Shuhei, Si, Sha, Manabe, Ichiro, Sanada, Masashi, Nakayama, Manabu, Masuko, Masayoshi, Sone, Hirohito, Koseki, Haruhiko, Iwama, Atsushi
Publicado 2017

Noncanonical EZH2 drives retinoic acid resistance of variant acute promyelocytic leukemias

por Poplineau, Mathilde, Platet, Nadine, Mazuel, Adrien, Hérault, Léonard, N’Guyen, Lia, Koide, Shuhei, Nakajima-Takagi, Yaeko, Kuribayashi, Wakako, Carbuccia, Nadine, Haboub, Loreen, Vernerey, Julien, Oshima, Motohiko, Birnbaum, Daniel, Iwama, Atsushi, Duprez, Estelle
Publicado 2022

Metformin, a Diabetes Drug, Eliminates Tumor-Initiating Hepatocellular Carcinoma Cells

por Saito, Tomoko, Chiba, Tetsuhiro, Yuki, Kaori, Zen, Yoh, Oshima, Motohiko, Koide, Shuhei, Motoyama, Tenyu, Ogasawara, Sadahisa, Suzuki, Eiichiro, Ooka, Yoshihiko, Tawada, Akinobu, Tada, Motohisa, Kanai, Fumihiko, Takiguchi, Yuichi, Iwama, Atsushi, Yokosuka, Osamu
Publicado 2013

Genome-Wide Mapping of Bivalent Histone Modifications in Hepatic Stem/Progenitor Cells

por Kanayama, Kengo, Chiba, Tetsuhiro, Oshima, Motohiko, Kanzaki, Hiroaki, Koide, Shuhei, Saraya, Atsunori, Miyagi, Satoru, Mimura, Naoya, Kusakabe, Yuko, Saito, Tomoko, Ogasawara, Sadahisa, Suzuki, Eiichiro, Ooka, Yoshihiko, Maruyama, Hitoshi, Iwama, Atsushi, Kato, Naoya
Publicado 2019

Clonal hematopoiesis with JAK2V617F promotes pulmonary hypertension with ALK1 upregulation in lung neutrophils

por Kimishima, Yusuke, Misaka, Tomofumi, Yokokawa, Tetsuro, Wada, Kento, Ueda, Koki, Sugimoto, Koichi, Minakawa, Keiji, Nakazato, Kazuhiko, Ishida, Takafumi, Oshima, Motohiko, Koide, Shuhei, Shide, Kotaro, Shimoda, Kazuya, Iwama, Atsushi, Ikeda, Kazuhiko, Takeishi, Yasuchika
Publicado 2021

Polycomb repressive complex 1.1 coordinates homeostatic and emergency myelopoiesis

por Nakajima-Takagi, Yaeko, Oshima, Motohiko, Takano, Junichiro, Koide, Shuhei, Itokawa, Naoki, Uemura, Shun, Yamashita, Masayuki, Andoh, Shohei, Aoyama, Kazumasa, Isshiki, Yusuke, Shinoda, Daisuke, Saraya, Atsunori, Arai, Fumio, Yamaguchi, Kiyoshi, Furukawa, Yoichi, Koseki, Haruhiko, Ikawa, Tomokatsu, Iwama, Atsushi
Publicado 2023

Disulfiram Eradicates Tumor-Initiating Hepatocellular Carcinoma Cells in ROS-p38 MAPK Pathway-Dependent and -Independent Manners

por Chiba, Tetsuhiro, Suzuki, Eiichiro, Yuki, Kaori, Zen, Yoh, Oshima, Motohiko, Miyagi, Satoru, Saraya, Atsunori, Koide, Shuhei, Motoyama, Tenyu, Ogasawara, Sadahisa, Ooka, Yoshihiko, Tawada, Akinobu, Nakatsura, Tetsuya, Hayashi, Takehiro, Yamashita, Taro, Kaneko, Syuichi, Miyazaki, Masaru, Iwama, Atsushi, Yokosuka, Osamu
Publicado 2014

A culture platform to study quiescent hematopoietic stem cells following genome editing

por Shiroshita, Kohei, Kobayashi, Hiroshi, Watanuki, Shintaro, Karigane, Daiki, Sorimachi, Yuriko, Fujita, Shinya, Tamaki, Shinpei, Haraguchi, Miho, Itokawa, Naoki, Aoyoama, Kazumasa, Koide, Shuhei, Masamoto, Yosuke, Kobayashi, Kenta, Nakamura-Ishizu, Ayako, Kurokawa, Mineo, Iwama, Atsushi, Okamoto, Shinichiro, Kataoka, Keisuke, Takubo, Keiyo
Publicado 2022

Efficacy of the novel tubulin polymerization inhibitor PTC‐028 for myelodysplastic syndrome

por Zhong, Cheng, Kayamori, Kensuke, Koide, Shuhei, Shinoda, Daisuke, Oshima, Motohiko, Nakajima‐Takagi, Yaeko, Nagai, Yurie, Mimura, Naoya, Sakaida, Emiko, Yamazaki, Satoshi, Iwano, Satoshi, Miyawaki, Atsushi, Ito, Ryoji, Tohyama, Kaoru, Yamaguchi, Kiyoshi, Furukawa, Yoichi, Lennox, William, Sheedy, Josephine, Weetall, Marla, Iwama, Atsushi
Publicado 2020

Histone lysine methyltransferase G9a is a novel epigenetic target for the treatment of hepatocellular carcinoma

por Yokoyama, Masayuki, Chiba, Tetsuhiro, Zen, Yoh, Oshima, Motohiko, Kusakabe, Yuko, Noguchi, Yoshiko, Yuki, Kaori, Koide, Shuhei, Tara, Shiro, Saraya, Atsunori, Aoyama, Kazumasa, Mimura, Naoya, Miyagi, Satoru, Inoue, Masanori, Wakamatsu, Toru, Saito, Tomoko, Ogasawara, Sadahisa, Suzuki, Eiichiro, Ooka, Yoshihiko, Tawada, Akinobu, Otsuka, Masayuki, Miyazaki, Masaru, Yokosuka, Osamu, Iwama, Atsushi
Publicado 2017

The combination of the tubulin binding small molecule PTC596 and proteasome inhibitors suppresses the growth of myeloma cells

por Nagai, Yurie, Mimura, Naoya, Rizq, Ola, Isshiki, Yusuke, Oshima, Motohiko, Rizk, Mohamed, Saraya, Atsunori, Koide, Shuhei, Nakajima-Takagi, Yaeko, Miyota, Makiko, Chiba, Tetsuhiro, Oshima-Hasegawa, Nagisa, Muto, Tomoya, Tsukamoto, Shokichi, Mitsukawa, Shio, Takeda, Yusuke, Ohwada, Chikako, Takeuchi, Masahiro, Iseki, Tohru, Nakaseko, Chiaki, Lennox, William, Sheedy, Josephine, Weetall, Marla, Yokote, Koutaro, Iwama, Atsushi, Sakaida, Emiko
Publicado 2021

Correction: UTX inactivation in germinal center B cells promotes the development of multiple myeloma with extramedullary disease

por Rizq, Ola, Mimura, Naoya, Oshima, Motohiko, Momose, Shuji, Takayama, Naoya, Itokawa, Naoki, Koide, Shuhei, Shibamiya, Asuka, Miyamoto-Nagai, Yurie, Rizk, Mohamed, Nakajima-Takagi, Yaeko, Aoyama, Kazumasa, Wang, Changshan, Saraya, Atsunori, Ito, Ryoji, Seimiya, Masanori, Watanabe, Mariko, Yamasaki, Satoshi, Shibata, Tatsuhiro, Yamaguchi, Kiyoshi, Furukawa, Yoichi, Chiba, Tetsuhiro, Sakaida, Emiko, Nakaseko, Chiaki, Tamaru, Jun-ichi, Tai, Yu-Tzu, Anderson, Kenneth C., Honda, Hiroaki, Iwama, Atsushi
Publicado 2023