Viral Vector-Based Innovative Approaches to Directly Abolishing Tumorigenic Pluripotent Stem Cells for Safer Regenerative Medicine

por Mitsui, Kaoru, Ide, Kanako, Takahashi, Tomoyuki, Kosai, Ken-ichiro
Publicado 2017

Adenovirus Biology, Recombinant Adenovirus, and Adenovirus Usage in Gene Therapy

por Watanabe, Maki, Nishikawaji, Yuya, Kawakami, Hirotaka, Kosai, Ken-ichiro
Publicado 2021

Alterations of Gene Expression and Glutamate Clearance in Astrocytes Derived from an MeCP2-Null Mouse Model of Rett Syndrome

por Okabe, Yasunori, Takahashi, Tomoyuki, Mitsumasu, Chiaki, Kosai, Ken-ichiro, Tanaka, Eiichiro, Matsuishi, Toyojiro
Publicado 2012

Conditionally replicating adenovirus prevents pluripotent stem cell–derived teratoma by specifically eliminating undifferentiated cells

por Mitsui, Kaoru, Ide, Kanako, Takayama, Akiko, Wada, Tadahisa, Irie, Rie, Kosai, Ken-ichiro
Publicado 2015

Activation of STAT3 by the Hepatitis C Virus Core Protein Leads to Cellular Transformation

por Yoshida, Takafumi, Hanada, Toshikatsu, Tokuhisa, Takeshi, Kosai, Ken-ichiro, Sata, Michio, Kohara, Michinori, Yoshimura, Akihiko
Publicado 2002

Efficient elimination of pancreatic cancer stem cells by hedgehog/GLI inhibitor GANT61 in combination with mTOR inhibition

por Miyazaki, Yumi, Matsubara, Shyuichirou, Ding, Qiang, Tsukasa, Koichiro, Yoshimitsu, Makoto, Kosai, Ken-ichiro, Takao, Sonshin
Publicado 2016

Intramuscular injection of adenoviral hepatocyte growth factor at a distal site ameliorates dextran sodium sulfate-induced colitis in mice

por YUGE, KENTARO, TAKAHASHI, TOMOYUKI, KHAI, NGIN CIN, GOTO, KAZUKO, FUJIWARA, TAKAKO, FUJIWARA, HISAYOSHI, KOSAI, KEN-ICHIRO
Publicado 2014

Heparin-binding epidermal growth factor-like growth factor and hepatocyte growth factor inhibit cholestatic liver injury in mice through different mechanisms

por Sakamoto, Kouichi, Khai, Ngin Cin, Wang, Yuqing, Irie, Rie, Takamatsu, Hideo, Matsufuji, Hiroshi, Kosai, Ken-Ichiro
Publicado 2016

A survivin-responsive, conditionally replicating adenovirus induces potent cytocidal effects in adult T-cell leukemia/lymphoma

por Suzuki, Shinsuke, Kofune, Hiroki, Uozumi, Kimiharu, Yoshimitsu, Makoto, Arima, Naomichi, Ishitsuka, Kenji, Ueno, Shin-ichi, Kosai, Ken-ichiro
Publicado 2019

Survivin-responsive conditionally replicating adenovirus kills rhabdomyosarcoma stem cells more efficiently than their progeny

por Tanoue, Kiyonori, Wang, Yuqing, Ikeda, Minako, Mitsui, Kaoru, Irie, Rie, Setoguchi, Takao, Komiya, Setsuro, Natsugoe, Shoji, Kosai, Ken-ichiro
Publicado 2014

FAD-dependent lysine-specific demethylase-1 regulates cellular energy expenditure

por Hino, Shinjiro, Sakamoto, Akihisa, Nagaoka, Katsuya, Anan, Kotaro, Wang, Yuqing, Mimasu, Shinya, Umehara, Takashi, Yokoyama, Shigeyuki, Kosai, Ken-ichiro, Nakao, Mitsuyoshi
Publicado 2012

Pathogenesis of Lethal Aspiration Pneumonia in Mecp2-null Mouse Model for Rett Syndrome

por Kida, Hiroshi, Takahashi, Tomoyuki, Nakamura, Yuki, Kinoshita, Takashi, Hara, Munetsugu, Okamoto, Masaki, Okayama, Satoko, Nakamura, Keiichiro, Kosai, Ken-ichiro, Taniwaki, Takayuki, Yamashita, Yushiro, Matsuishi, Toyojiro
Publicado 2017

Disturbance of cardiac gene expression and cardiomyocyte structure predisposes Mecp2-null mice to arrhythmias

por Hara, Munetsugu, Takahashi, Tomoyuki, Mitsumasu, Chiaki, Igata, Sachiyo, Takano, Makoto, Minami, Tomoko, Yasukawa, Hideo, Okayama, Satoko, Nakamura, Keiichiro, Okabe, Yasunori, Tanaka, Eiichiro, Takemura, Genzou, Kosai, Ken-ichiro, Yamashita, Yushiro, Matsuishi, Toyojiro
Publicado 2015