CRISPR/Cas9 Epigenome Editing Potential for Rare Imprinting Diseases: A Review

por Syding, Linn Amanda, Nickl, Petr, Kasparek, Petr, Sedlacek, Radislav
Publicado 2020

NPFFR2-deficient mice fed a high-fat diet develop strong intolerance to glucose

por Karnošová, Alena, Strnadová, Veronika, Železná, Blanka, Kuneš, Jaroslav, Kašpárek, Petr, Maletínská, Lenka
Publicado 2023

CRL4-DCAF12 Ubiquitin Ligase Controls MOV10 RNA Helicase during Spermatogenesis and T Cell Activation

por Lidak, Tomas, Baloghova, Nikol, Korinek, Vladimir, Sedlacek, Radislav, Balounova, Jana, Kasparek, Petr, Cermak, Lukas
Publicado 2021

ADAM10 and ADAM17 regulate EGFR, c-Met and TNF RI signalling in liver regeneration and fibrosis

por Zbodakova, Olga, Chalupsky, Karel, Sarnova, Lenka, Kasparek, Petr, Jirouskova, Marketa, Gregor, Martin, Sedlacek, Radislav
Publicado 2021

Generation and Characterization of a Novel Angelman Syndrome Mouse Model with a Full Deletion of the Ube3a Gene

por Syding, Linn Amanda, Kubik-Zahorodna, Agnieszka, Nickl, Petr, Novosadova, Vendula, Kopkanova, Jana, Kasparek, Petr, Prochazka, Jan, Sedlacek, Radislav
Publicado 2022

KLK5 and KLK7 Ablation Fully Rescues Lethality of Netherton Syndrome-Like Phenotype

por Kasparek, Petr, Ileninova, Zuzana, Zbodakova, Olga, Kanchev, Ivan, Benada, Oldrich, Chalupsky, Karel, Brattsand, Maria, Beck, Inken M., Sedlacek, Radislav
Publicado 2017

The iRhom2/ADAM17 Axis Attenuates Bacterial Uptake by Phagocytes in a Cell Autonomous Manner

por Seifert, Anke, Wozniak, Justyna, Düsterhöft, Stefan, Kasparek, Petr, Sedlacek, Radislav, Dreschers, Stephan, Orlikowsky, Thorsten W., Yildiz, Daniela, Ludwig, Andreas
Publicado 2020

FBXO38 Ubiquitin Ligase Controls Sertoli Cell Maturation

por Dibus, Nikol, Zobalova, Eliska, Monleon, Mario A. M., Korinek, Vladimir, Filipp, Dominik, Petrusova, Jana, Sedlacek, Radislav, Kasparek, Petr, Cermak, Lukas
Publicado 2022

Comprehensive Transcriptional Profiling and Mouse Phenotyping Reveals Dispensable Role for Adipose Tissue Selective Long Noncoding RNA Gm15551

por Engelhard, Christoph Andreas, Huang, Chien, Khani, Sajjad, Kasparek, Petr, Prochazka, Jan, Rozman, Jan, Reguera, David Pajuelo, Sedlacek, Radislav, Kornfeld, Jan-Wilhelm
Publicado 2022

Molecular interactions of adaptor protein PSTPIP2 control neutrophil-mediated responses leading to autoinflammation

por Pavliuchenko, Nataliia, Duric, Iris, Kralova, Jarmila, Fabisik, Matej, Spoutil, Frantisek, Prochazka, Jan, Kasparek, Petr, Pokorna, Jana, Skopcova, Tereza, Sedlacek, Radislav, Brdicka, Tomas
Publicado 2022

TALEN-Based HvMPK3 Knock-Out Attenuates Proteome and Root Hair Phenotypic Responses to flg22 in Barley

por Takáč, Tomáš, Křenek, Pavel, Komis, George, Vadovič, Pavol, Ovečka, Miroslav, Ohnoutková, Ludmila, Pechan, Tibor, Kašpárek, Petr, Tichá, Tereza, Basheer, Jasim, Arick, Mark, Šamaj, Jozef
Publicado 2021

Generation and characterization of human U-2 OS cell lines with the CRISPR/Cas9-edited protoporphyrinogen oxidase IX gene

por Novakova, Zora, Milosevic, Mirko, Kutil, Zsofia, Ondrakova, Marketa, Havlinova, Barbora, Kasparek, Petr, Sandoval-Acuña, Cristian, Korandova, Zuzana, Truksa, Jaroslav, Vrbacky, Marek, Rohlena, Jakub, Barinka, Cyril
Publicado 2022

Intronic Determinants Coordinate Charme lncRNA Nuclear Activity through the Interaction with MATR3 and PTBP1

por Desideri, Fabio, Cipriano, Andrea, Petrezselyova, Silvia, Buonaiuto, Giulia, Santini, Tiziana, Kasparek, Petr, Prochazka, Jan, Janson, Giacomo, Paiardini, Alessandro, Calicchio, Alessandro, Colantoni, Alessio, Sedlacek, Radislav, Bozzoni, Irene, Ballarino, Monica
Publicado 2020

The iRhom homology domain is indispensable for ADAM17-mediated TNFα and EGF receptor ligand release

por Düsterhöft, Stefan, Kahveci-Türköz, Selcan, Wozniak, Justyna, Seifert, Anke, Kasparek, Petr, Ohm, Henrike, Liu, Shixin, Kopkanova, Jana, Lokau, Juliane, Garbers, Christoph, Preisinger, Christian, Sedlacek, Radislav, Freeman, Matthew, Ludwig, Andreas
Publicado 2021

Ablation of Gabra5 Influences Corticosterone Levels and Anxiety-like Behavior in Mice

por Syding, Linn Amanda, Kubik-Zahorodna, Agnieszka, Reguera, David Pajuelo, Nickl, Petr, Hruskova, Bohdana, Kralikova, Michaela, Kopkanova, Jana, Novosadova, Vendula, Kasparek, Petr, Prochazka, Jan, Rozman, Jan, Turecek, Rostislav, Sedlacek, Radislav
Publicado 2023

A structural model of the iRhom–ADAM17 sheddase complex reveals functional insights into its trafficking and activity

por Kahveci-Türköz, Selcan, Bläsius, Katharina, Wozniak, Justyna, Rinkens, Cindy, Seifert, Anke, Kasparek, Petr, Ohm, Henrike, Oltzen, Shixin, Nieszporek, Martin, Schwarz, Nicole, Babendreyer, Aaron, Preisinger, Christian, Sedlacek, Radislav, Ludwig, Andreas, Düsterhöft, Stefan
Publicado 2023

Early evolution of enamel matrix proteins is reflected by pleiotropy of physiological functions

por Spoutil, Frantisek, Aranaz-Novaliches, Goretti, Prochazkova, Michaela, Wald, Tomas, Novosadova, Vendula, Kasparek, Petr, Osicka, Radim, Reseland, Janne E., Lyngstadaas, Staale P., Tiainen, Hanna, Bousova, Kristyna, Vondrasek, Jiri, Sedlacek, Radislav, Prochazka, Jan
Publicado 2023

Truncated PPM1D impairs stem cell response to genotoxic stress and promotes growth of APC-deficient tumors in the mouse colon

por Burocziova, Monika, Burdova, Kamila, Martinikova, Andra S., Kasparek, Petr, Kleiblova, Petra, Danielsen, Stine A., Borecka, Marianna, Jenikova, Gabriela, Janečková, Lucie, Pavel, Jozef, Zemankova, Petra, Schneiderova, Michaela, Schwarzova, Lucie, Ticha, Ivana, Sun, Xiao-Feng, Jiraskova, Katerina, Liska, Vaclav, Vodickova, Ludmila, Vodicka, Pavel, Sedlacek, Radislav, Kleibl, Zdenek, Lothe, Ragnhild A., Korinek, Vladimír, Macurek, Libor
Publicado 2019

A previously uncharacterized Factor Associated with Metabolism and Energy (FAME/C14orf105/CCDC198/1700011H14Rik) is related to evolutionary adaptation, energy balance, and kidney p...

por Petersen, Julian, Englmaier, Lukas, Artemov, Artem V., Poverennaya, Irina, Mahmoud, Ruba, Bouderlique, Thibault, Tesarova, Marketa, Deviatiiarov, Ruslan, Szilvásy-Szabó, Anett, Akkuratov, Evgeny E., Pajuelo Reguera, David, Zeberg, Hugo, Kaucka, Marketa, Kastriti, Maria Eleni, Krivanek, Jan, Radaszkiewicz, Tomasz, Gömöryová, Kristína, Knauth, Sarah, Potesil, David, Zdrahal, Zbynek, Ganji, Ranjani Sri, Grabowski, Anna, Buhl, Miriam E., Zikmund, Tomas, Kavkova, Michaela, Axelson, Håkan, Lindgren, David, Kramann, Rafael, Kuppe, Christoph, Erdélyi, Ferenc, Máté, Zoltán, Szabó, Gábor, Koehne, Till, Harkany, Tibor, Fried, Kaj, Kaiser, Jozef, Boor, Peter, Fekete, Csaba, Rozman, Jan, Kasparek, Petr, Prochazka, Jan, Sedlacek, Radislav, Bryja, Vitezslav, Gusev, Oleg, Adameyko, Igor
Publicado 2023

Author Correction: A previously uncharacterized Factor Associated with Metabolism and Energy (FAME/C14orf105/CCDC198/1700011H14Rik) is related to evolutionary adaptation, energy ba...

por Petersen, Julian, Englmaier, Lukas, Artemov, Artem V., Poverennaya, Irina, Mahmoud, Ruba, Bouderlique, Thibault, Tesarova, Marketa, Deviatiiarov, Ruslan, Szilvásy-Szabó, Anett, Akkuratov, Evgeny E., Pajuelo Reguera, David, Zeberg, Hugo, Kaucka, Marketa, Kastriti, Maria Eleni, Krivanek, Jan, Radaszkiewicz, Tomasz, Gömöryová, Kristína, Knauth, Sarah, Potesil, David, Zdrahal, Zbynek, Ganji, Ranjani Sri, Grabowski, Anna, Buhl, Miriam E., Zikmund, Tomas, Kavkova, Michaela, Axelson, Håkan, Lindgren, David, Kramann, Rafael, Kuppe, Christoph, Erdélyi, Ferenc, Máté, Zoltán, Szabó, Gábor, Koehne, Till, Harkany, Tibor, Fried, Kaj, Kaiser, Jozef, Boor, Peter, Fekete, Csaba, Rozman, Jan, Kasparek, Petr, Prochazka, Jan, Sedlacek, Radislav, Bryja, Vitezslav, Gusev, Oleg, Adameyko, Igor
Publicado 2023