Mechanism of the formation of DNA–protein cross-links by antitumor cisplatin

por Chválová, Kateřina, Brabec, Viktor, Kašpárková, Jana
Publicado 2007

Walking of antitumor bifunctional trinuclear Pt(II) complex on double-helical DNA

por Malina, Jaroslav, Kasparkova, Jana, Farrell, Nicholas P., Brabec, Viktor
Publicado 2011

Inhibition of nuclear factor kappaB proteins-platinated DNA interactions correlates with cytotoxic effectiveness of the platinum complexes

por Brabec, Viktor, Kasparkova, Jana, Kostrhunova, Hana, Farrell, Nicholas P.
Publicado 2016

Chiral discrimination in platinum anticancer drugs.

por Benedetti, Michele, Malina, Jaroslav, Kasparkova, Jana, Brabec, Viktor, Natile, Giovanni
Publicado 2002

Simultaneous delivery of olaparib and carboplatin in PEGylated liposomes imparts this drug combination hypersensitivity and selectivity for breast tumor cells

por Novohradsky, Vojtech, Zajac, Juraj, Vrana, Oldrich, Kasparkova, Jana, Brabec, Viktor
Publicado 2018

Correction: Simultaneous delivery of olaparib and carboplatin in PEGylated liposomes imparts this drug combination hypersensitivity and selectivity for breast tumor cells

por Novohradsky, Vojtech, Zajac, Juraj, Vrana, Oldrich, Kasparkova, Jana, Brabec, Viktor
Publicado 2018

Conformation, protein recognition and repair of DNA interstrand and intrastrand cross-links of Antitumor trans-[PtCl(2)(NH(3))(thiazole)]

por Marini, Victoria, Christofis, Petros, Novakova, Olga, Kasparkova, Jana, Farrell, Nicholas, Brabec, Viktor
Publicado 2005

An anticancer Os(II) bathophenanthroline complex as a human breast cancer stem cell-selective, mammosphere potent agent that kills cells by necroptosis

por Novohradsky, Vojtech, Markova, Lenka, Kostrhunova, Hana, Trávníček, Zdeněk, Brabec, Viktor, Kasparkova, Jana
Publicado 2019

Gallium(III) Complex with Cloxyquin Ligands Induces Ferroptosis in Cancer Cells and Is a Potent Agent against Both Differentiated and Tumorigenic Cancer Stem Rhabdomyosarcoma Cells

por Hreusova, Monika, Novohradsky, Vojtech, Markova, Lenka, Kostrhunova, Hana, Potočňák, Ivan, Brabec, Viktor, Kasparkova, Jana
Publicado 2022

Potentiating Effect of UVA Irradiation on Anticancer Activity of Carboplatin Derivatives Involving 7-Azaindoles

por Štarha, Pavel, Trávníček, Zdeněk, Dvořák, Zdeněk, Radošová-Muchová, Tereza, Prachařová, Jitka, Vančo, Ján, Kašpárková, Jana
Publicado 2015

Platinum(IV) Derivatives of [Pt(1S,2S-diaminocyclohexane)(5,6-dimethyl-1,10-phenanthroline)] with Diclofenac Ligands in the Axial Positions: A New Class of Potent Multi-action Agen...

por Kostrhunova, Hana, McGhie, Brondwyn S., Markova, Lenka, Novakova, Olga, Kasparkova, Jana, Aldrich-Wright, Janice R., Brabec, Viktor
Publicado 2023

Epigenetic and antitumor effects of platinum(IV)-octanoato conjugates

por Novohradsky, Vojtech, Zanellato, Ilaria, Marzano, Cristina, Pracharova, Jitka, Kasparkova, Jana, Gibson, Dan, Gandin, Valentina, Osella, Domenico, Brabec, Viktor
Publicado 2017

Palladium and Platinum Complexes of the Antimetabolite Fludarabine with Vastly Enhanced Selectivity for Tumour over Non-Malignant Cells

por Schleser, Sebastian W., Krytovych, Oleksandr, Ziegelmeier, Tim, Groß, Elisabeth, Kasparkova, Jana, Brabec, Viktor, Weber, Thomas, Schobert, Rainer, Mueller, Thomas
Publicado 2023

Ruthenium(II)–Tris-pyrazolylmethane Complexes Inhibit Cancer Cell Growth by Disrupting Mitochondrial Calcium Homeostasis

por Cervinka, Jakub, Gobbo, Alberto, Biancalana, Lorenzo, Markova, Lenka, Novohradsky, Vojtech, Guelfi, Massimo, Zacchini, Stefano, Kasparkova, Jana, Brabec, Viktor, Marchetti, Fabio
Publicado 2022

DNA‐Intercalative Platinum Anticancer Complexes Photoactivated by Visible Light

por Shi, Huayun, Kasparkova, Jana, Soulié, Clément, Clarkson, Guy J., Imberti, Cinzia, Novakova, Olga, Paterson, Martin J., Brabec, Viktor, Sadler, Peter J.
Publicado 2021

Cyclometalated Benzimidazole Osmium(II) Complexes with Antiproliferative Activity in Cancer Cells Disrupt Calcium Homeostasis

por Hernández-García, Alba, Marková, Lenka, Santana, María Dolores, Prachařová, Jitka, Bautista, Delia, Kostrhunová, Hana, Novohradský, Vojtěch, Brabec, Viktor, Ruiz, José, Kašpárková, Jana
Publicado 2023

Novel cis-Pt(II) Complexes with Alkylpyrazole Ligands: Synthesis, Characterization, and Unusual Mode of Anticancer Action

por Kasparkova, Jana, Kostrhunova, Hana, Novohradsky, Vojtech, Logvinov, Аlexey A., Temnov, Viktor V., Borisova, Nataliya E., Podrugina, Tatiana A., Markova, Lenka, Starha, Pavel, Nazarov, Alexey. A., Brabec, Viktor
Publicado 2022

Glycoconjugated Metallohelices have Improved Nuclear Delivery and Suppress Tumour Growth In Vivo

por Song, Hualong, Allison, Simon J., Brabec, Viktor, Bridgewater, Hannah E., Kasparkova, Jana, Kostrhunova, Hana, Novohradsky, Vojtech, Phillips, Roger M., Pracharova, Jitka, Rogers, Nicola J., Shepherd, Samantha L., Scott, Peter
Publicado 2020

Transfer Hydrogenation and Antiproliferative Activity of Tethered Half-Sandwich Organoruthenium Catalysts

por Chen, Feng, Romero-Canelón, Isolda, Soldevila-Barreda, Joan J., Song, Ji-Inn, Coverdale, James P. C., Clarkson, Guy J., Kasparkova, Jana, Habtemariam, Abraha, Wills, Martin, Brabec, Viktor, Sadler, Peter J.
Publicado 2018

Diazido Mixed-Amine Platinum(IV) Anticancer Complexes Activatable by Visible-Light Form Novel DNA Adducts

por Zhao, Yao, Woods, Julie A, Farrer, Nicola J, Robinson, Kim S, Pracharova, Jitka, Kasparkova, Jana, Novakova, Olga, Li, Huilin, Salassa, Luca, Pizarro, Ana M, Clarkson, Guy J, Song, Lijiang, Brabec, Viktor, Sadler, Peter J
Publicado 2013