Chromosome separation during Drosophila male meiosis I requires separase-mediated cleavage of the homolog conjunction protein UNO

por Weber, Joe, Kabakci, Zeynep, Chaurasia, Soumya, Brunner, Erich, Lehner, Christian F.
Publicado 2020

Teflon promotes chromosomal recruitment of homolog conjunction proteins during Drosophila male meiosis

por Kabakci, Zeynep, Yamada, Hiro, Vernizzi, Luisa, Gupta, Samir, Weber, Joe, Sun, Michael Shoujie, Lehner, Christian F.
Publicado 2022

Homologous chromosomes are stably conjoined for Drosophila male meiosis I by SUM, a multimerized protein assembly with modules for DNA-binding and for separase-mediated dissociatio...

por Kabakci, Zeynep, Reichle, Heidi E., Lemke, Bianca, Rousova, Dorota, Gupta, Samir, Weber, Joe, Schleiffer, Alexander, Weir, John R., Lehner, Christian F.
Publicado 2022

Pharmacophore-guided discovery of CDC25 inhibitors causing cell cycle arrest and tumor regression

por Kabakci, Zeynep, Käppeli, Simon, Cantù, Claudio, Jensen, Lasse D., König, Christiane, Toggweiler, Janine, Gentili, Christian, Ribaudo, Giovanni, Zagotto, Giuseppe, Basler, Konrad, Pinna, Lorenzo A., Cozza, Giorgio, Ferrari, Stefano
Publicado 2019