Small-molecule screening of PC3 prostate cancer cells identifies tilorone dihydrochloride to selectively inhibit cell growth based on cyclin-dependent kinase 5 expression

por WISSING, MICHEL D., DADON, TIKVA, KIM, EUNICE, PIONTEK, KLAUS B., SHIM, JOONG S., KAELBER, NADINE S., LIU, JUN O., KACHHAP, SUSHANT K., NELKIN, BARRY D.
Publicado 2014

HIF1 and ID1 Interplay Confers Adaptive Survival to HIF1α-Inhibition

por Geng, Hao, Ko, Hyun-Kyung, Pittsenbarger, Janet, Harvey, Christopher T., Xue, Changhui, Liu, Qiong, Wiens, Sadie, Kachhap, Sushant K., Beer, Tomasz M., Qian, David Z.
Publicado 2021

The N-Myc Down Regulated Gene1 (NDRG1) Is a Rab4a Effector Involved in Vesicular Recycling of E-Cadherin

por Kachhap, Sushant K., Faith, Dennis, Qian, David Z., Shabbeer, Shabana, Galloway, Nathan L., Pili, Roberto, Denmeade, Samuel R., DeMarzo, Angelo M., Carducci, Michael A.
Publicado 2007

Downregulation of Homologous Recombination DNA Repair Genes by HDAC Inhibition in Prostate Cancer Is Mediated through the E2F1 Transcription Factor

por Kachhap, Sushant K., Rosmus, Nadine, Collis, Spencer J., Kortenhorst, Madeleine S. Q., Wissing, Michel D., Hedayati, Mohammad, Shabbeer, Shabana, Mendonca, Janet, Deangelis, Justin, Marchionni, Luigi, Lin, Jianqing, Höti, Naseruddin, Nortier, Johan W. R., DeWeese, Theodore L., Hammers, Hans, Carducci, Michael A.
Publicado 2010

Combining the pan-aurora kinase inhibitor AMG 900 with histone deacetylase inhibitors enhances antitumor activity in prostate cancer

por Paller, Channing J, Wissing, Michel D, Mendonca, Janet, Sharma, Anup, Kim, Eugene, Kim, Hea-Soo, Kortenhorst, Madeleine S Q, Gerber, Stephanie, Rosen, Marc, Shaikh, Faraz, Zahurak, Marianna L, Rudek, Michelle A, Hammers, Hans, Rudin, Charles M, Carducci, Michael A, Kachhap, Sushant K
Publicado 2014

Interplay between hypoxia and androgen controls a metabolic switch conferring resistance to androgen/AR-targeted therapy

por Geng, Hao, Xue, Changhui, Mendonca, Janet, Sun, Xiao-Xin, Liu, Qiong, Reardon, Patrick N., Chen, Yingxiao, Qian, Kendrick, Hua, Vivian, Chen, Alice, Pan, Freddy, Yuan, Julia, Dang, Sang, Beer, Tomasz M., Dai, Mu-Shui, Kachhap, Sushant K., Qian, David Z.
Publicado 2018

Publisher Correction: Interplay between hypoxia and androgen controls a metabolic switch conferring resistance to androgen/AR-targeted therapy

por Geng, Hao, Xue, Changhui, Mendonca, Janet, Sun, Xiao-Xin, Liu, Qiong, Reardon, Patrick N., Chen, Yingxiao, Qian, Kendrick, Hua, Vivian, Chen, Alice, Pan, Freddy, Yuan, Julia, Dang, Sang, Beer, Tomasz M., Dai, Mu-Shui, Kachhap, Sushant K., Qian, David Z.
Publicado 2019

Phase I Trial of Intravenous Mistletoe Extract in Advanced Cancer

por Paller, Channing J., Wang, Lin, Fu, Wei, Kumar, Rajendra, Durham, Jennifer N., Azad, Nilofer S., Laheru, Daniel A., Browner, Ilene, Kachhap, Sushant K., Boyapati, Kavya, Odeny, Thomas, Armstrong, Deborah K., Meyer, Christian F., Gaillard, Stephanie, Brahmer, Julie R., Page, Ivelisse, Wang, Hao, Diaz, Luis A.
Publicado 2023

Muscadine grape skin extract inhibits prostate cancer cells by inducing cell-cycle arrest, and decreasing migration through heat shock protein 40

por Ignacio, Diane N., Mason, Kimberly D., Hackett-Morton, Ezra C., Albanese, Christopher, Ringer, Lymor, Wagner, William D., Wang, Paul C., Carducci, Michael A., Kachhap, Sushant K., Paller, Channing J., Mendonca, Janet, Li-Ying Chan, Leo, Lin, Bo, Hartle, Diane K., Green, Jeffrey E., Brown, Collis A., Hudson, Tamaro S.
Publicado 2019

Androgen receptor activity in prostate cancer dictates efficacy of bipolar androgen therapy through MYC

por Sena, Laura A., Kumar, Rajendra, Sanin, David E., Thompson, Elizabeth A., Rosen, D. Marc, Dalrymple, Susan L., Antony, Lizamma, Yang, Yuhan, Gomes-Alexandre, Carolina, Hicks, Jessica L., Jones, Tracy, Bowers, Kiara A., Eskra, Jillian N., Meyers, Jennifer, Gupta, Anuj, Skaist, Alyza, Yegnasubramanian, Srinivasan, Luo, Jun, Brennen, W. Nathaniel, Kachhap, Sushant K., Antonarakis, Emmanuel S., De Marzo, Angelo M., Isaacs, John T., Markowski, Mark C., Denmeade, Samuel R.
Publicado 2022