Prevention of guanylyl cyclase–B dephosphorylation rescues achondroplastic dwarfism

por Wagner, Brandon M., Robinson, Jerid W., Lin, Yun-Wen, Lee, Yi-Ching, Kaci, Nabil, Legeai-Mallet, Laurence, Potter, Lincoln R.
Publicado 2021

The Impairment of MAGMAS Function in Human Is Responsible for a Severe Skeletal Dysplasia

por Mehawej, Cybel, Delahodde, Agnès, Legeai-Mallet, Laurence, Delague, Valérie, Kaci, Nabil, Desvignes, Jean-Pierre, Kibar, Zoha, Capo-Chichi, José-Mario, Chouery, Eliane, Munnich, Arnold, Cormier-Daire, Valérie, Mégarbané, André
Publicado 2014

Meckel’s and condylar cartilages anomalies in achondroplasia result in defective development and growth of the mandible

por Biosse Duplan, Martin, Komla-Ebri, Davide, Heuzé, Yann, Estibals, Valentin, Gaudas, Emilie, Kaci, Nabil, Benoist-Lasselin, Catherine, Zerah, Michel, Kramer, Ina, Kneissel, Michaela, Porta, Diana Grauss, Di Rocco, Federico, Legeai-Mallet, Laurence
Publicado 2016

Hypochondroplasia gain-of-function mutation in FGFR3 causes defective bone mineralization in mice

por Loisay, Léa, Komla-Ebri, Davide, Morice, Anne, Heuzé, Yann, Viaut, Camille, de La Seiglière, Amélie, Kaci, Nabil, Chan, Danny, Lamouroux, Audrey, Baujat, Geneviève, Bassett, J.H. Duncan, Williams, Graham R., Legeai-Mallet, Laurence
Publicado 2023

Phosphatase inhibition by LB-100 enhances BMN-111 stimulation of bone growth

por Shuhaibar, Leia C., Kaci, Nabil, Egbert, Jeremy R., Horville, Thibault, Loisay, Léa, Vigone, Giulia, Uliasz, Tracy F., Dambroise, Emilie, Swingle, Mark R., Honkanen, Richard E., Duplan, Martin Biosse, Jaffe, Laurinda A., Legeai-Mallet, Laurence
Publicado 2021

Theobroma cacao improves bone growth by modulating defective ciliogenesis in a mouse model of achondroplasia

por Martin, Ludovic, Kaci, Nabil, Benoist-Lasselin, Catherine, Mondoloni, Marine, Decaudaveine, Suzanne, Estibals, Valentin, Cornille, Maxence, Loisay, Léa, Flipo, Justine, Demuynck, Benoît, de la Luz Cádiz-Gurrea, Maria, Barbault, Florent, Fernández-Arroyo, Salvador, Schibler, Laurent, Segura-Carretero, Antonio, Dambroise, Emilie, Legeai-Mallet, Laurence
Publicado 2022

FGFR3 overactivation in the brain is responsible for memory impairments in Crouzon syndrome mouse model

por Cornille, Maxence, Moriceau, Stéphanie, Khonsari, Roman H., Heuzé, Yann, Loisay, Léa, Boitez, Valérie, Morice, Anne, Arnaud, Eric, Collet, Corinne, Bensidhoum, Morad, Kaci, Nabil, Boddaert, Nathalie, Paternoster, Giovanna, Rauschendorfer, Theresa, Werner, Sabine, Mansour, Suzanne L., Di Rocco, Federico, Oury, Franck, Legeai-Mallet, Laurence
Publicado 2022