Reconstruction of the Cytokine Signaling in Lysosomal Storage Diseases by Literature Mining and Network Analysis

por Parolo, Silvia, Tomasoni, Danilo, Bora, Pranami, Ramponi, Alan, Kaddi, Chanchala, Azer, Karim, Domenici, Enrico, Neves-Zaph, Susana, Lombardo, Rosario
Publicado 2021

QSPcc reduces bottlenecks in computational model simulations

por Tomasoni, Danilo, Paris, Alessio, Giampiccolo, Stefano, Reali, Federico, Simoni, Giulia, Marchetti, Luca, Kaddi, Chanchala, Neves-Zaph, Susana, Priami, Corrado, Azer, Karim, Lombardo, Rosario
Publicado 2021

History and Future Perspectives on the Discipline of Quantitative Systems Pharmacology Modeling and Its Applications

por Azer, Karim, Kaddi, Chanchala D., Barrett, Jeffrey S., Bai, Jane P. F., McQuade, Sean T., Merrill, Nathaniel J., Piccoli, Benedetto, Neves-Zaph, Susana, Marchetti, Luca, Lombardo, Rosario, Parolo, Silvia, Immanuel, Selva Rupa Christinal, Baliga, Nitin S.
Publicado 2021

Quantitative Systems Pharmacology Modeling of Acid Sphingomyelinase Deficiency and the Enzyme Replacement Therapy Olipudase Alfa Is an Innovative Tool for Linking Pathophysiology a...

por Kaddi, Chanchala D., Niesner, Bradley, Baek, Rena, Jasper, Paul, Pappas, John, Tolsma, John, Li, Jing, van Rijn, Zachary, Tao, Mengdi, Ortemann‐Renon, Catherine, Easton, Rachael, Tan, Sharon, Puga, Ana Cristina, Schuchman, Edward H., Barrett, Jeffrey S., Azer, Karim
Publicado 2018

A Quantitative Systems Pharmacology Model of Gaucher Disease Type 1 Provides Mechanistic Insight Into the Response to Substrate Reduction Therapy With Eliglustat

por Abrams, Ruth, Kaddi, Chanchala D., Tao, Mengdi, Leiser, Randolph J., Simoni, Giulia, Reali, Federico, Tolsma, John, Jasper, Paul, van Rijn, Zachary, Li, Jing, Niesner, Bradley, Barrett, Jeffrey S., Marchetti, Luca, Peterschmitt, M. Judith, Azer, Karim, Neves‐Zaph, Susana
Publicado 2020