A rare subpopulation of melanoma cells with low expression of metastasis suppressor NME1 is highly metastatic in vivo

por Snyder, Devin, Wang, Ying, Kaetzel, David M.
Publicado 2020

NM23 deficiency promotes metastasis in a UV radiation-induced mouse model of human melanoma

por Jarrett, Stuart G., Novak, Marian, Harris, Nathan, Merlino, Glenn, Slominski, Andrezj, Kaetzel, David M.
Publicado 2012

Pigmented Epithelioid Melanocytoma (PEM)/Animal Type Melanoma (ATM): Quest for an Origin. Report of One Unusual Case Indicating Follicular Origin and Another Arising in an Intrader...

por Tarasen, Ashley, Carlson, J. Andrew, Leonard, M. Kathryn, Merlino, Glenn, Kaetzel, David, Slominski, Andrzej T.
Publicado 2017

The HGF/SF Mouse Model of UV-Induced Melanoma as an In Vivo Sensor for Metastasis-Regulating Gene

por Leonard, M. Kathryn, Pamidimukkala, Nidhi, Puts, Gemma S., Snyder, Devin E., Slominski, Andrzej T., Kaetzel, David M.
Publicado 2017

Metastasis suppressor NME1 regulates melanoma cell morphology, self‐adhesion and motility via induction of fibronectin expression

por Novak, Marián, Leonard, Mary Kathryn, Yang, Xiuwei H., Kowluru, Anjan, Belkin, Alexey M., Kaetzel, David M.
Publicado 2015

Identification of a gene expression signature associated with the metastasis suppressor function of NME1: prognostic value in human melanoma

por Leonard, M. Kathryn, McCorkle, Joseph R., Snyder, Devin, Novak, Marian, Zhang, Qingbei, Shetty, Amol, Mahurkar, Anup A., Kaetzel, David M.
Publicado 2017

Nme1 and Nme2 genes exert metastasis-suppressor activities in a genetically engineered mouse model of UV-induced melanoma

por Pamidimukkala, Nidhi, Puts, Gemma S., Kathryn Leonard, M., Snyder, Devin, Dabernat, Sandrine, De Fabo, Edward C., Noonan, Frances P., Slominski, Andrzej, Merlino, Glenn, Kaetzel, David M.
Publicado 2020

c-Abl and Arg are activated in human primary melanomas, promote melanoma cell invasion via distinct pathways, and drive metastatic progression

por Ganguly, Sourik S., Fiore, Leann S., Sims, Jonathan T., Friend, J. Woodrow, Srinivasan, Divyamani, Thacker, Matthew A., Cibull, Michael L., Wang, Chi, Novak, Marian, Kaetzel, David M., Plattner, Rina
Publicado 2011

Harvesting multipotent progenitor cells from a small sample of tonsillar biopsy for clinical applications

por Khatri, Raju, Arad, Michal, Ortlip, Timothy, Portney, Benjamin A., Meltzer, W. Alex, Diaconu, Silviu, Silipino, Lorna E., Wang, Ying, Kaetzel, David M., Taylor, Rodney J., Zalzman, Michal
Publicado 2017

Metastasis Suppressor NME1 Modulates Choice of Double-Strand Break Repair Pathways in Melanoma Cells by Enhancing Alternative NHEJ while Inhibiting NHEJ and HR

por Puts, Gemma, Jarrett, Stuart, Leonard, Mary, Matsangos, Nicolette, Snyder, Devin, Wang, Ying, Vincent, Richard, Portney, Benjamin, Abbotts, Rachel, McLaughlin, Lena, Zalzman, Michal, Rassool, Feyruz, Kaetzel, David
Publicado 2020

c-Abl and Arg induce cathepsin-mediated lysosomal degradation of the NM23-H1 metastasis suppressor in invasive cancer

por Fiore, Leann S., Ganguly, Sourik S., Sledziona, James, Cibull, Michael L., Wang, Chi, Richards, Dana L., Neltner, Janna M., Beach, Carol, McCorkle, Joseph R., Kaetzel, David M., Plattner, Rina
Publicado 2013

CD151-α3β1 integrin complexes suppress ovarian tumor growth by repressing slug-mediated EMT and canonical Wnt signaling

por Baldwin, Lauren A., Hoff, John T., Lefringhouse, Jason, Zhang, Michael, Jia, Changhe, Liu, Zeyi, Erfani, Sonia, Jin, Hongyan, Xu, Mei, She, Qing-Bai, van Nagell, John R., Wang, Chi, Chen, Li, Plattner, Rina, Kaetzel, David M., Luo, Jia, Lu, Michael, West, Dava, Liu, Chunming, Ueland, Fred R., Drapkin, Ronny, Zhou, Binhua P., Yang, Xiuwei H.
Publicado 2014

Comprehensive molecular profiling of UV-induced metastatic melanoma in Nme1/Nme2-deficient mice reveals novel markers of survival in human patients

por Leonard, M. Kathryn, Puts, Gemma S., Pamidimukkala, Nidhi, Adhikary, Gautam, Xu, Yili, Kwok, Eric, Jin, Yuxin, Snyder, Devin, Matsangos, Nicolette, Novak, Marián, Mahurkar, Anup, Shetty, Amol C., Slominski, Radomir M., De Fabo, Edward C., Noonan, Frances P., Day, Chi-Ping, Rigi, Mohammed, Slominski, Andrzej T., Webb, Michelle G., Craig, David W., Merlino, Glenn, Eckert, Richard L., Carpten, John D., Manojlovic, Zarko, Kaetzel, David M.
Publicado 2021