Innate immune detection of lipid oxidation as a threat assessment strategy

por Zhivaki, Dania, Kagan, Jonathan C.
Publicado 2021

Protocol to purify recombinant inflammatory caspases and assess their catalytic activity in vitro

por Devant, Pascal, Kagan, Jonathan C.
Publicado 2022

Microbial strategies for antagonizing Toll-like-Receptor signal transduction

por Rosadini, Charles V., Kagan, Jonathan C.
Publicado 2015

Lipids that directly regulate innate immune signal transduction

por Barnett, Katherine C, Kagan, Jonathan C
Publicado 2019

Interferon-Independent Restriction of RNA Virus Entry and Replication by a Class of Damage-Associated Molecular Patterns

por Ernandes, Michael J., Kagan, Jonathan C.
Publicado 2021

Diverse Control Mechanisms of the Interleukin-1 Cytokine Family

por Evavold, Charles L., Kagan, Jonathan C.
Publicado 2022

Lipopolysaccharide detection by the innate immune system may be an uncommon defence strategy used in nature

por Gauthier, Anna E., Rotjan, Randi D., Kagan, Jonathan C.
Publicado 2022

Legionella Subvert the Functions of Rab1 and Sec22b to Create a Replicative Organelle

por Kagan, Jonathan C., Stein, Mary-Pat, Pypaert, Marc, Roy, Craig R.
Publicado 2004

Heterologous Expression and Assembly of Human TLR Signaling Components in Saccharomyces cerevisiae

por Coronas-Serna, Julia María, del Val, Elba, Kagan, Jonathan C., Molina, María, Cid, Víctor J.
Publicado 2021

Hepatitis C virus NS3‐4A inhibits the peroxisomal MAVS‐dependent antiviral signalling response

por Ferreira, Ana R., Magalhães, Ana C., Camões, Fátima, Gouveia, Ana, Vieira, Marta, Kagan, Jonathan C., Ribeiro, Daniela
Publicado 2016

Human Cytomegalovirus vMIA Inhibits MAVS Oligomerization at Peroxisomes in an MFF-Dependent Manner

por Ferreira, Ana Rita, Gouveia, Ana, Magalhães, Ana Cristina, Valença, Isabel, Marques, Mariana, Kagan, Jonathan C., Ribeiro, Daniela
Publicado 2022

Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-κB Signaling Adaptation

por de Oliveira Mann, Carina C., Orzalli, Megan H., King, David S., Kagan, Jonathan C., Lee, Amy S.Y., Kranzusch, Philip J.
Publicado 2019

Diverse intracellular pathogens activate Type III Interferon expression from peroxisomes

por Odendall, Charlotte, Dixit, Evelyn, Stavru, Fabrizia, Bierne, Helene, Franz, Kate M., Fiegen, Ann, Boulant, Steeve, Gehrke, Lee, Cossart, Pascale, Kagan, Jonathan C.
Publicado 2014

Gasdermin D pore-forming activity is redox-sensitive

por Devant, Pascal, Boršić, Elvira, Ngwa, Elsy M., Xiao, Haopeng, Chouchani, Edward T., Thiagarajah, Jay R., Hafner-Bratkovič, Iva, Evavold, Charles L., Kagan, Jonathan C.
Publicado 2023

Ultrasound-responsive low-dose doxorubicin liposomes trigger mitochondrial DNA release and activate cGAS-STING-mediated antitumour immunity

por Wang, Chaoyu, Zhang, Ruoshi, He, Jia, Yu, Lvshan, Li, Xinyan, Zhang, Junxia, Li, Sai, Zhang, Conggang, Kagan, Jonathan C., Karp, Jeffrey M., Kuai, Rui
Publicado 2023

Peroxisomes are platforms for cytomegalovirus’ evasion from the cellular immune response

por Magalhães, Ana Cristina, Ferreira, Ana Rita, Gomes, Sílvia, Vieira, Marta, Gouveia, Ana, Valença, Isabel, Islinger, Markus, Nascimento, Rute, Schrader, Michael, Kagan, Jonathan C., Ribeiro, Daniela
Publicado 2016

Inflammasomes within Hyperactive Murine Dendritic Cells Stimulate Long-Lived T Cell-Mediated Anti-tumor Immunity

por Zhivaki, Dania, Borriello, Francesco, Chow, Ohn A., Doran, Benjamin, Fleming, Ira, Theisen, Derek J., Pallis, Paris, Shalek, Alex K., Sokol, Caroline L., Zanoni, Ivan, Kagan, Jonathan C.
Publicado 2020

TBK1 and IKKε act like an OFF switch to limit NLRP3 inflammasome pathway activation

por Fischer, Fabian A., Mies, Linda F. M., Nizami, Sohaib, Pantazi, Eirini, Danielli, Sara, Demarco, Benjamin, Ohlmeyer, Michael, Lee, Michelle Sue Jann, Coban, Cevayir, Kagan, Jonathan C., Di Daniel, Elena, Bezbradica, Jelena S.
Publicado 2021

Glycine inhibits NINJ1 membrane clustering to suppress plasma membrane rupture in cell death

por Borges, Jazlyn P, Sætra, Ragnhild SR, Volchuk, Allen, Bugge, Marit, Devant, Pascal, Sporsheim, Bjørnar, Kilburn, Bridget R, Evavold, Charles L, Kagan, Jonathan C, Goldenberg, Neil M, Flo, Trude Helen, Steinberg, Benjamin Ethan
Publicado 2022

Control of the innate immune response by the mevalonate pathway

por Akula, Murali K., Shi, Man, Jiang, Zhaozhao, Foster, Celia E., Miao, David, Li, Annie S., Zhang, Xiaoman, Gavin, Ruth M., Forde, Sorcha D., Germain, Gail, Carpenter, Susan, Rosadini, Charles V., Gritsman, Kira, Chae, Jae Jin, Hampton, Randolph, Silverman, Neal, Gravallese, Ellen M., Kagan, Jonathan C., Fitzgerald, Katherine A., Kastner, Daniel L., Golenbock, Douglas T., Bergo, Martin O., Wang, Donghai
Publicado 2016