The new-generation selective ROS1/NTRK inhibitor DS-6051b overcomes crizotinib resistant ROS1-G2032R mutation in preclinical models

por Katayama, Ryohei, Gong, Bo, Togashi, Noriko, Miyamoto, Masaya, Kiga, Masaki, Iwasaki, Shiho, Kamai, Yasuki, Tominaga, Yuichi, Takeda, Yasuyuki, Kagoshima, Yoshiko, Shimizu, Yuki, Seto, Yosuke, Oh-hara, Tomoko, Koike, Sumie, Nakao, Naoki, Hanzawa, Hiroyuki, Watanabe, Kengo, Yoda, Satoshi, Yanagitani, Noriko, Hata, Aaron N., Shaw, Alice T., Nishio, Makoto, Fujita, Naoya, Isoyama, Takeshi
Publicado 2019

A novel Menin-MLL1 inhibitor, DS-1594a, prevents the progression of acute leukemia with rearranged MLL1 or mutated NPM1

por Numata, Masashi, Haginoya, Noriyasu, Shiroishi, Machiko, Hirata, Tsuyoshi, Sato-Otsubo, Aiko, Yoshikawa, Kenji, Takata, Yoshimi, Nagase, Reina, Kashimoto, Yoshinori, Suzuki, Makoto, Schulte, Nina, Polier, Gernot, Kurimoto, Akiko, Tomoe, Yumiko, Toyota, Akiko, Yoneyama, Tomoko, Imai, Emi, Watanabe, Kenji, Hamada, Tomoaki, Kanada, Ryutaro, Watanabe, Jun, Kagoshima, Yoshiko, Tokumaru, Eri, Murata, Kenji, Baba, Takayuki, Shinozaki, Taeko, Ohtsuka, Masami, Goto, Koichi, Karibe, Tsuyoshi, Deguchi, Takao, Gocho, Yoshihiro, Yoshida, Masanori, Tomizawa, Daisuke, Kato, Motohiro, Tsutsumi, Shinji, Kitagawa, Mayumi, Abe, Yuki
Publicado 2023