AF4 and AF4-MLL mediate transcriptional elongation of 5-lipoxygenase mRNA by 1, 25-dihydroxyvitamin D(3)

por Ahmad, Khalil, Scholz, Bastian, Capelo, Ricardo, Schweighöfer, Ilona, Kahnt, Astrid Stefanie, Marschalek, Rolf, Steinhilber, Dieter
Publicado 2015

Urate transporter inhibitor lesinurad is a selective peroxisome proliferator-activated receptor gamma modulator (sPPARγM) in vitro

por Heitel, Pascal, Gellrich, Leonie, Heering, Jan, Goebel, Tamara, Kahnt, Astrid, Proschak, Ewgenij, Schubert-Zsilavecz, Manfred, Merk, Daniel
Publicado 2018

Three-dimensional growth reveals fine-tuning of 5-lipoxygenase by proliferative pathways in cancer

por Göbel, Tamara, Goebel, Bjarne, Hyprath, Marius, Lamminger, Ira, Weisser, Hannah, Angioni, Carlo, Mathes, Marius, Thomas, Dominique, Kahnt, Astrid S
Publicado 2023

Knock-out of 5-lipoxygenase in overexpressing tumor cells—consequences on gene expression and cellular function

por Weisser, Hannah, Göbel, Tamara, Melissa Krishnathas, G., Kreiß, Marius, Angioni, Carlo, Sürün, Duran, Thomas, Dominique, Schmid, Tobias, Häfner, Ann-Kathrin, Kahnt, Astrid S.
Publicado 2022

Inhibitors of Human 5-Lipoxygenase Potently Interfere With Prostaglandin Transport

por Kahnt, Astrid S., Angioni, Carlo, Göbel, Tamara, Hofmann, Bettina, Roos, Jessica, Steinbrink, Svenja D., Rörsch, Florian, Thomas, Dominique, Geisslinger, Gerd, Zacharowski, Kai, Grösch, Sabine, Steinhilber, Dieter, Maier, Thorsten J.
Publicado 2022

Structural Modifications Yield Novel Insights Into the Intriguing Pharmacodynamic Potential of Anti-inflammatory Nitro-Fatty Acids

por Hellmuth, Nadine, Brat, Camilla, Awad, Omar, George, Sven, Kahnt, Astrid, Bauer, Tom, Huynh Phuoc, Hai Phong, Steinhilber, Dieter, Angioni, Carlo, Hassan, Mohamed, Hock, Katharina J., Manolikakes, Georg, Zacharowski, Kai, Roos, Jessica, Maier, Thorsten J.
Publicado 2021

Zafirlukast Is a Dual Modulator of Human Soluble Epoxide Hydrolase and Peroxisome Proliferator-Activated Receptor γ

por Göbel, Tamara, Diehl, Olaf, Heering, Jan, Merk, Daniel, Angioni, Carlo, Wittmann, Sandra K., Buscato, Estel.la, Kottke, Ramona, Weizel, Lilia, Schader, Tim, Maier, Thorsten J., Geisslinger, Gerd, Schubert-Zsilavecz, Manfred, Steinhilber, Dieter, Proschak, Ewgenij, Kahnt, Astrid S.
Publicado 2019

Formation, Signaling and Occurrence of Specialized Pro-Resolving Lipid Mediators—What is the Evidence so far?

por Schebb, Nils Helge, Kühn, Hartmut, Kahnt, Astrid S., Rund, Katharina M., O’Donnell, Valerie B., Flamand, Nicolas, Peters-Golden, Marc, Jakobsson, Per-Johan, Weylandt, Karsten H., Rohwer, Nadine, Murphy, Robert C., Geisslinger, Gerd, FitzGerald, Garret A., Hanson, Julien, Dahlgren, Claes, Alnouri, Mohamad Wessam, Offermanns, Stefan, Steinhilber, Dieter
Publicado 2022