Synthesis, gene silencing activity, thermal stability, and serum stability of siRNA containing four (S)-5′-C-aminopropyl-2′-O-methylnucleosides (A, adenosine; U, uridine; G, guanos...

por Kajino, Ryohei, Sakamoto, Shuichi, Ueno, Yoshihito
Publicado 2022

Synthesis and evaluation of (S)-5′-C-aminopropyl and (S)-5′-C-aminopropyl-2′-arabinofluoro modified DNA oligomers for novel RNase H-dependent antisense oligonucleotides

por Zhou, Yujun, Kajino, Ryohei, Ishii, Seiichiro, Yamagishi, Kenji, Ueno, Yoshihito
Publicado 2020

Synthesis of siRNAs incorporated with cationic peptides R8G7 and R8A7 and the effect of the modifications on siRNA properties

por Matsubara, Miho, Honda, Kenji, Ozaki, Koki, Kajino, Ryohei, Kakisawa, Yuri, Maeda, Yusuke, Ueno, Yoshihito
Publicado 2020