Antitumor activity of the MEK inhibitor trametinib on intestinal polyp formation in Apc(Δ716) mice involves stromal COX-2

por Fujishita, Teruaki, Kajino-Sakamoto, Rie, Kojima, Yasushi, Taketo, Makoto Mark, Aoki, Masahiro
Publicado 2015

Intestinal Epithelial-Derived TAK1 Signaling Is Essential for Cytoprotection against Chemical-Induced Colitis

por Kim, Jae-Young, Kajino-Sakamoto, Rie, Omori, Emily, Jobin, Christian, Ninomiya-Tsuji, Jun
Publicado 2009

TAK1 kinase determines TRAIL sensitivity by modulating reactive oxygen species and cIAP

por Morioka, Sho, Omori, Emily, Kajino, Taisuke, Kajino-Sakamoto, Rie, Matsumoto, Kunihiro, Ninomiya-Tsuji, Jun
Publicado 2009

Stromal iodothyronine deiodinase 2 (DIO2) promotes the growth of intestinal tumors in Apc (Δ716) mutant mice

por Kojima, Yasushi, Kondo, Yuriko, Fujishita, Teruaki, Mishiro‐Sato, Emi, Kajino‐Sakamoto, Rie, Taketo, Makoto Mark, Aoki, Masahiro
Publicado 2019

Decreased liver B vitamin-related enzymes as a metabolic hallmark of cancer cachexia

por Kojima, Yasushi, Mishiro-Sato, Emi, Fujishita, Teruaki, Satoh, Kiyotoshi, Kajino-Sakamoto, Rie, Oze, Isao, Nozawa, Kazuki, Narita, Yukiya, Ogata, Takatsugu, Matsuo, Keitaro, Muro, Kei, Taketo, Makoto Mark, Soga, Tomoyoshi, Aoki, Masahiro
Publicado 2023

L-2hydroxyglutaric acid rewires amino acid metabolism in colorectal cancer via the mTOR-ATF4 axis

por Tabata, Sho, Kojima, Yasushi, Sakamoto, Takeharu, Igarashi, Kaori, Umetsu, Ko, Ishikawa, Takamasa, Hirayama, Akiyoshi, Kajino-Sakamoto, Rie, Sakamoto, Naoya, Yasumoto, Ken-ichi, Okano, Keiichi, Suzuki, Yasuyuki, Yachida, Shinichi, Aoki, Masahiro, Soga, Tomoyoshi
Publicado 2023