The acidic pathway of bile acid synthesis: Not just an alternative pathway(☆)

por Pandak, William M., Kakiyama, Genta
Publicado 2019

Mitochondrial Cholesterol Metabolites in a Bile Acid Synthetic Pathway Drive Nonalcoholic Fatty Liver Disease: A Revised “Two-Hit” Hypothesis

por Kakiyama, Genta, Rodriguez-Agudo, Daniel, Pandak, William M.
Publicado 2023

Profiling of Urinary Glucuronidated Bile Acids across Age Groups

por Muto, Yamato, Suzuki, Mitsuyoshi, Kakiyama, Genta, Sasaki, Takahiro, Murai, Tsuyoshi, Takei, Hajime, Nittono, Hiroshi
Publicado 2022

Characterization of long-chain fatty acid-linked bile acids: a major conjugation form of 3β-hydroxy bile acids in feces

por Takei, Hajime, Narushima, Seiko, Suzuki, Mitsuyoshi, Kakiyama, Genta, Sasaki, Takahiro, Murai, Tsuyoshi, Yamashiro, Yuichiro, Nittono, Hiroshi
Publicado 2022

Identification of Novel Regulatory Cholesterol Metabolite, 5-Cholesten, 3β,25-Diol, Disulfate

por Ren, Shunlin, Kim, Jin Koung, Kakiyama, Genta, Rodriguez-Agudo, Daniel, Pandak, William M., Min, Hae-Ki, Ning, Yanxia
Publicado 2014

Fxr signaling and microbial metabolism of bile salts in the zebrafish intestine

por Wen, Jia, Mercado, Gilberto Padilla, Volland, Alyssa, Doden, Heidi L., Lickwar, Colin R., Crooks, Taylor, Kakiyama, Genta, Kelly, Cecelia, Cocchiaro, Jordan L., Ridlon, Jason M., Rawls, John F.
Publicado 2021

Berberine Prevents Disease Progression of Nonalcoholic Steatohepatitis through Modulating Multiple Pathways

por Wang, Yanyan, Tai, Yun-Ling, Zhao, Derrick, Zhang, Yuan, Yan, Junkai, Kakiyama, Genta, Wang, Xuan, Gurley, Emily C., Liu, Jinze, Liu, Jinpeng, Liu, Jimin, Lai, Guanhua, Hylemon, Phillip B., Pandak, William M., Chen, Weidong, Zhou, Huiping
Publicado 2021

Insulin dysregulation drives mitochondrial cholesterol metabolite accumulation: initiating hepatic toxicity in nonalcoholic fatty liver disease

por Minowa, Kei, Rodriguez-Agudo, Daniel, Suzuki, Mitsuyoshi, Muto, Yamato, Hirai, Saeko, Wang, Yaping, Su, Lianyong, Zhou, Huiping, Chen, Qun, Lesnefsky, Edward J., Mitamura, Kuniko, Ikegawa, Shigeo, Takei, Hajime, Nittono, Hiroshi, Fuchs, Michael, Pandak, William M., Kakiyama, Genta
Publicado 2023

Gut microbial composition can differentially regulate bile acid synthesis in humanized mice

por Kang, Dae Joong, Hylemon, Phillip B, Gillevet, Patrick M, Sartor, R. Balfour, Betrapally, Naga S., Kakiyama, Genta, Sikaroodi, Masoumeh, Takei, Hajime, Nittono, Hiroshi, Zhou, Huiping, Pandak, William M., Yang, Jing, Jiao, Chunhua, Li, Xiaojiaoyang, Lippman, H. Robert, Heuman, Douglas M., Bajaj, Jasmohan S.
Publicado 2017

Berberine alters gut microbial function through modulation of bile acids

por Wolf, Patricia G., Devendran, Saravanan, Doden, Heidi L., Ly, Lindsey K., Moore, Tyler, Takei, Hajime, Nittono, Hiroshi, Murai, Tsuyoshi, Kurosawa, Takao, Chlipala, George E., Green, Stefan J., Kakiyama, Genta, Kashyap, Purna, McCracken, Vance J., Gaskins, H. Rex, Gillevet, Patrick M., Ridlon, Jason M.
Publicado 2021

Rifaximin Exerts Beneficial Effects Independent of its Ability to Alter Microbiota Composition

por Kang, Dae J, Kakiyama, Genta, Betrapally, Naga S, Herzog, Jeremy, Nittono, Hiroshi, Hylemon, Phillip B, Zhou, Huiping, Carroll, Ian, Yang, Jing, Gillevet, Patrick M, Jiao, Chunhua, Takei, Hajime, Pandak, William M, Iida, Takashi, Heuman, Douglas M, Fan, Sili, Fiehn, Oliver, Kurosawa, Takao, Sikaroodi, Masoumeh, Sartor, R B, Bajaj, Jasmohan S
Publicado 2016