Design and Synthesis of Novel Hybrid 8-Hydroxy Quinoline-Indole Derivatives as Inhibitors of Aβ Self-Aggregation and Metal Chelation-Induced Aβ Aggregation

por Bowroju, Suresh K., Mainali, Nirjal, Ayyadevara, Srinivas, Penthala, Narsimha R., Krishnamachari, Sesha, Kakraba, Samuel, Reis, Robert J. Shmookler, Crooks, Peter A.
Publicado 2020

Aggregate Interactome Based on Protein Cross-linking Interfaces Predicts Drug Targets to Limit Aggregation in Neurodegenerative Diseases

por Balasubramaniam, Meenakshisundaram, Ayyadevara, Srinivas, Ganne, Akshatha, Kakraba, Samuel, Penthala, Narsimha Reddy, Du, Xiuxia, Crooks, Peter A., Griffin, Sue T., Shmookler Reis, Robert J.
Publicado 2019

Thiadiazolidinone (TDZD) Analogs Inhibit Aggregation-Mediated Pathology in Diverse Neurodegeneration Models, and Extend C. elegans Life- and Healthspan

por Kakraba, Samuel, Ayyadevara, Srinivas, Mainali, Nirjal, Balasubramaniam, Meenakshisundaram, Bowroju, Suresh, Penthala, Narsimha Reddy, Atluri, Ramani, Barger, Steven W., Griffin, Sue T., Crooks, Peter A., Shmookler Reis, Robert J.
Publicado 2023

A Novel Microtubule-Binding Drug Attenuates and Reverses Protein Aggregation in Animal Models of Alzheimer’s Disease

por Kakraba, Samuel, Ayyadevara, Srinivas, Penthala, Narsimha Reddy, Balasubramaniam, Meenakshisundaram, Ganne, Akshatha, Liu, Ling, Alla, Ramani, Bommagani, Shoban Babu, Barger, Steven W., Griffin, W. Sue T., Crooks, Peter A., Shmookler Reis, Robert J.
Publicado 2019