Knowledge-guided gene prioritization reveals new insights into the mechanisms of chemoresistance

por Emad, Amin, Cairns, Junmei, Kalari, Krishna R., Wang, Liewei, Sinha, Saurabh
Publicado 2017

Transcriptome-Wide Analysis of UTRs in Non-Small Cell Lung Cancer Reveals Cancer-Related Genes with SNV-Induced Changes on RNA Secondary Structure and miRNA Target Sites

por Sabarinathan, Radhakrishnan, Wenzel, Anne, Novotny, Peter, Tang, Xiaojia, Kalari, Krishna R., Gorodkin, Jan
Publicado 2014

Mapping the dynamics of insulin-responsive pathways in the blood–brain barrier endothelium using time-series transcriptomics data

por Wang, Zengtao, Tang, Xiaojia, Swaminathan, Suresh K., Kandimalla, Karunya K., Kalari, Krishna R.
Publicado 2022

Identification of genetic variants or genes that are associated with Homoharringtonine (HHT) response through a genome-wide association study in human lymphoblastoid cell lines (LC...

por Tong, Yin, Niu, Nifang, Jenkins, Gregory, Batzler, Anthony, Li, Liang, Kalari, Krishna R., Wang, Liewei
Publicado 2015

Cell-level somatic mutation detection from single-cell RNA sequencing

por Vu, Trung Nghia, Nguyen, Ha-Nam, Calza, Stefano, Kalari, Krishna R, Wang, Liewei, Pawitan, Yudi
Publicado 2019

Frequency of MicroRNA Response Elements Identifies Pathologically Relevant Signaling Pathways in Triple-Negative Breast Cancer

por Nair, Asha A., Tang, Xiaojia, Thompson, Kevin J., Vedell, Peter T., Kalari, Krishna R., Subramanian, Subbaya
Publicado 2020

CDC25B partners with PP2A to induce AMPK activation and tumor suppression in triple negative breast cancer

por Cairns, Junmei, Ly, Reynold C, Niu, Nifang, Kalari, Krishna R, Carlson, Erin E, Wang, Liewei
Publicado 2020

Alternating EM algorithm for a bilinear model in isoform quantification from RNA-seq data

por Deng, Wenjiang, Mou, Tian, Kalari, Krishna R, Niu, Nifang, Wang, Liewei, Pawitan, Yudi, Vu, Trung Nghia
Publicado 2019

Isoform-level gene expression patterns in single-cell RNA-sequencing data

por Vu, Trung Nghia, Wills, Quin F, Kalari, Krishna R, Niu, Nifang, Wang, Liewei, Pawitan, Yudi, Rantalainen, Mattias
Publicado 2018

SLCO1B1: Application and Limitations of Deep Mutational Scanning for Genomic Missense Variant Function

por Zhang, Lingxin, Sarangi, Vivekananda, Ho, Ming-Fen, Moon, Irene, Kalari, Krishna R., Wang, Liewei, Weinshilboum, Richard M.
Publicado 2021

Copy number variation and cytidine analogue cytotoxicity: A genome-wide association approach

por Kalari, Krishna R, Hebbring, Scott J, Chai, High Seng, Li, Liang, Kocher, Jean-Pierre A, Wang, Liewei, Weinshilboum, Richard M
Publicado 2010

Circular RNAs and their associations with breast cancer subtypes

por Nair, Asha A., Niu, Nifang, Tang, Xiaojia, Thompson, Kevin J., Wang, Liewei, Kocher, Jean-Pierre, Subramanian, Subbaya, Kalari, Krishna R.
Publicado 2016

Stochastic changes in gene expression promote chaotic dysregulation of homeostasis in clonal breast tumors

por Felts, Sara J., Tang, Xiaojia, Willett, Benjamin, Van Keulen, Virginia P., Hansen, Michael J., Kalari, Krishna R., Pease, Larry R.
Publicado 2019

The lncRNA MIR2052HG regulates ERα levels and aromatase inhibitor resistance through LMTK3 by recruiting EGR1

por Cairns, Junmei, Ingle, James N., Kalari, Krishna R., Shepherd, Lois E., Kubo, Michiaki, Goetz, Matthew P., Weinshilboum, Richard M., Wang, Liewei
Publicado 2019

CYP2C9 and CYP2C19: Deep Mutational Scanning and Functional Characterization of Genomic Missense Variants

por Zhang, Lingxin, Sarangi, Vivekananda, Moon, Irene, Yu, Jia, Liu, Duan, Devarajan, Sandhya, Reid, Joel M., Kalari, Krishna R., Wang, Liewei, Weinshilboum, Richard
Publicado 2020

Model-based unsupervised learning informs metformin-induced cell-migration inhibition through an AMPK-independent mechanism in breast cancer

por Athreya, Arjun P., Kalari, Krishna R., Cairns, Junmei, Gaglio, Alan J., Wills, Quin F., Niu, Nifang, Weinshilboum, Richard, Iyer, Ravishankar K., Wang, Liewei
Publicado 2017

Gene expression in the corneal endothelium of Fuchs endothelial corneal dystrophy patients with and without expansion of a trinucleotide repeat in TCF4

por Wieben, Eric D., Aleff, Ross A., Tang, Xiaojia, Kalari, Krishna R., Maguire, Leo J., Patel, Sanjay V., Baratz, Keith H., Fautsch, Michael P.
Publicado 2018

Gene Expression and Missplicing in the Corneal Endothelium of Patients With a TCF4 Trinucleotide Repeat Expansion Without Fuchs' Endothelial Corneal Dystrophy

por Wieben, Eric D., Baratz, Keith H., Aleff, Ross A., Kalari, Krishna R., Tang, Xiaojia, Maguire, Leo J., Patel, Sanjay V., Fautsch, Michael P.
Publicado 2019

Plasma Copy Number Alteration-Based Prognostic and Predictive Multi-Gene Risk Score in Metastatic Castration-Resistant Prostate Cancer

por Huang, Jinyong, Du, Meijun, Soupir, Alex, Wang, Liewei, Tan, Winston, Kalari, Krishna R., Kilari, Deepak, Park, Jong, Huang, Chiang-Ching, Kohli, Manish, Wang, Liang
Publicado 2022

BBBomics-Human Blood Brain Barrier Transcriptomics Hub

por Kalari, Krishna R., Thompson, Kevin J., Nair, Asha A., Tang, Xiaojia, Bockol, Matthew A., Jhawar, Navya, Swaminathan, Suresh K., Lowe, Val J., Kandimalla, Karunya K.
Publicado 2016