Guiding Lights in Genome Editing for Inherited Retinal Disorders: Implications for Gene and Cell Therapy

por Sanjurjo-Soriano, Carla, Kalatzis, Vasiliki
Publicado 2018

Identification and Characterisation of the Murine Homologue of the Gene Responsible for Cystinosis, Ctns

por Cherqui, Stéphanie, Kalatzis, Vasiliki, Forestier, Lionel, Poras, Isabelle, Antignac, Corinne
Publicado 2000

Genome Editing as a Treatment for the Most Prevalent Causative Genes of Autosomal Dominant Retinitis Pigmentosa

por Diakatou, Michalitsa, Manes, Gaël, Bocquet, Beatrice, Meunier, Isabelle, Kalatzis, Vasiliki
Publicado 2019

Allele-Specific Knockout by CRISPR/Cas to Treat Autosomal Dominant Retinitis Pigmentosa Caused by the G56R Mutation in NR2E3

por Diakatou, Michalitsa, Dubois, Gregor, Erkilic, Nejla, Sanjurjo-Soriano, Carla, Meunier, Isabelle, Kalatzis, Vasiliki
Publicado 2021

Corneal Transduction by Intra-Stromal Injection of AAV Vectors In Vivo in the Mouse and Ex Vivo in Human Explants

por Hippert, Claire, Ibanes, Sandy, Serratrice, Nicolas, Court, Franck, Malecaze, François, Kremer, Eric J., Kalatzis, Vasiliki
Publicado 2012

Genome Editing in Patient iPSCs Corrects the Most Prevalent USH2A Mutations and Reveals Intriguing Mutant mRNA Expression Profiles

por Sanjurjo-Soriano, Carla, Erkilic, Nejla, Baux, David, Mamaeva, Daria, Hamel, Christian P., Meunier, Isabelle, Roux, Anne-Françoise, Kalatzis, Vasiliki
Publicado 2019

Preclinical pharmacology of a lipophenol in a mouse model of light-induced retinopathy

por Taveau, Nicolas, Cubizolle, Aurélie, Guillou, Laurent, Pinquier, Nicolas, Moine, Espérance, Cia, David, Kalatzis, Vasiliki, Vercauteren, Joseph, Durand, Thierry, Crauste, Céline, Brabet, Philippe
Publicado 2020

The effect of PTC124 on choroideremia fibroblasts and iPSC-derived RPE raises considerations for therapy

por Torriano, Simona, Erkilic, Nejla, Baux, David, Cereso, Nicolas, De Luca, Valerie, Meunier, Isabelle, Moosajee, Mariya, Roux, Anne-Francoise, Hamel, Christian P., Kalatzis, Vasiliki
Publicado 2018

Identification of the First Single GSDME Exon 8 Structural Variants Associated with Autosomal Dominant Hearing Loss

por Mansard, Luke, Vaché, Christel, Bianchi, Julie, Baudoin, Corinne, Perthus, Isabelle, Isidor, Bertrand, Blanchet, Catherine, Baux, David, Koenig, Michel, Kalatzis, Vasiliki, Roux, Anne-Françoise
Publicado 2022

Proof of concept for AAV2/5-mediated gene therapy in iPSC-derived retinal pigment epithelium of a choroideremia patient

por Cereso, Nicolas, Pequignot, Marie O, Robert, Lorenne, Becker, Fabienne, De Luca, Valerie, Nabholz, Nicolas, Rigau, Valerie, De Vos, John, Hamel, Christian P, Kalatzis, Vasiliki
Publicado 2014

Nonsense-mediated mRNA decay efficiency varies in choroideremia providing a target to boost small molecule therapeutics

por Sarkar, Hajrah, Mitsios, Andreas, Smart, Matthew, Skinner, Jane, Welch, Ailsa A, Kalatzis, Vasiliki, Coffey, Peter J, Dubis, Adam M, Webster, Andrew R, Moosajee, Mariya
Publicado 2019

USH2A variants causing retinitis pigmentosa or Usher syndrome provoke differential retinal phenotypes in disease-specific organoids

por Sanjurjo-Soriano, Carla, Jimenez-Medina, Carla, Erkilic, Nejla, Cappellino, Luisina, Lefevre, Arnaud, Nagel-Wolfrum, Kerstin, Wolfrum, Uwe, Van Wijk, Erwin, Roux, Anne-Françoise, Meunier, Isabelle, Kalatzis, Vasiliki
Publicado 2023

Retinoic acid delays initial photoreceptor differentiation and results in a highly structured mature retinal organoid

por Sanjurjo-Soriano, Carla, Erkilic, Nejla, Damodar, Krishna, Boukhaddaoui, Hassan, Diakatou, Michalitsa, Garita-Hernandez, Marcela, Mamaeva, Daria, Dubois, Gregor, Jazouli, Zhour, Jimenez-Medina, Carla, Goureau, Olivier, Meunier, Isabelle, Kalatzis, Vasiliki
Publicado 2022

SPACR Encoded by IMPG1 Is Essential for Photoreceptor Survival by Interplaying between the Interphotoreceptor Matrix and the Retinal Pigment Epithelium

por Olivier, Guillaume, Brabet, Philippe, Pirot, Nelly, Broyon, Morgane, Guillou, Laurent, Cazevieille, Chantal, Sar, Chamroeun, Quiles, Melanie, Sarzi, Emmanuelle, Pequignot, Marie, Andreo, Ervann, Roubertie, Agathe, Meunier, Isabelle, Muller, Agnès, Kalatzis, Vasiliki, Manes, Gaël
Publicado 2022

A Novel Chromosomal Translocation Identified due to Complex Genetic Instability in iPSC Generated for Choroideremia

por Erkilic, Nejla, Gatinois, Vincent, Torriano, Simona, Bouret, Pauline, Sanjurjo-Soriano, Carla, De Luca, Valerie, Damodar, Krishna, Cereso, Nicolas, Puechberty, Jacques, Sanchez-Alcudia, Rocio, Hamel, Christian P., Ayuso, Carmen, Meunier, Isabelle, Pellestor, Franck, Kalatzis, Vasiliki
Publicado 2019

Zika virus induces strong inflammatory responses and impairs homeostasis and function of the human retinal pigment epithelium

por Simonin, Yannick, Erkilic, Nejla, Damodar, Krishna, Clé, Marion, Desmetz, Caroline, Bolloré, Karine, Taleb, Mehdi, Torriano, Simona, Barthelemy, Jonathan, Dubois, Grégor, Lajoix, Anne Dominique, Foulongne, Vincent, Tuaillon, Edouard, Van de Perre, Philippe, Kalatzis, Vasiliki, Salinas, Sara
Publicado 2018

The Cell Adhesion Molecule “CAR” and Sialic Acid on Human Erythrocytes Influence Adenovirus In Vivo Biodistribution

por Seiradake, Elena, Henaff, Daniel, Wodrich, Harald, Billet, Olivier, Perreau, Matthieu, Hippert, Claire, Mennechet, Franck, Schoehn, Guy, Lortat-Jacob, Hugues, Dreja, Hanna, Ibanes, Sandy, Kalatzis, Vasiliki, Wang, Jennifer P., Finberg, Robert W., Cusack, Stephen, Kremer, Eric J.
Publicado 2009

Lysosomal and network alterations in human mucopolysaccharidosis type VII iPSC-derived neurons

por Bayó-Puxan, Neus, Terrasso, Ana Paula, Creyssels, Sophie, Simão, Daniel, Begon-Pescia, Christina, Lavigne, Marina, Salinas, Sara, Bernex, Florence, Bosch, Assumpció, Kalatzis, Vasiliki, Levade, Thierry, Cuervo, Ana Maria, Lory, Philippe, Consiglio, Antonella, Brito, Catarina, Kremer, Eric J.
Publicado 2018

Study of Usutu virus neuropathogenicity in mice and human cellular models

por Clé, Marion, Barthelemy, Jonathan, Desmetz, Caroline, Foulongne, Vincent, Lapeyre, Lina, Bolloré, Karine, Tuaillon, Edouard, Erkilic, Nejla, Kalatzis, Vasiliki, Lecollinet, Sylvie, Beck, Cécile, Pirot, Nelly, Glasson, Yaël, Gosselet, Fabien, Alvarez Martinez, Maria Teresa, Van de Perre, Philippe, Salinas, Sara, Simonin, Yannick
Publicado 2020

CRB1-Related Retinal Dystrophies in a Cohort of 50 Patients: A Reappraisal in the Light of Specific Müller Cell and Photoreceptor CRB1 Isoforms

por Mairot, Kévin, Smirnov, Vasily, Bocquet, Béatrice, Labesse, Gilles, Arndt, Carl, Defoort-Dhellemmes, Sabine, Zanlonghi, Xavier, Hamroun, Dalil, Denis, Danièle, Picot, Marie-Christine, David, Thierry, Grunewald, Olivier, Pégart, Mako, Huguet, Hélèna, Roux, Anne-Françoise, Kalatzis, Vasiliki, Dhaenens, Claire-Marie, Meunier, Isabelle
Publicado 2021