Native RNA Purification Method for Small RNA Molecules Based on Asymmetrical Flow Field-Flow Fractionation

por Levanova, Alesia A., Lampi, Mirka, Kalke, Kiira, Hukkanen, Veijo, Poranen, Minna M., Eskelin, Katri
Publicado 2022

Attenuated Replication-Competent Herpes Simplex Virus Expressing an ECM-Modifying Transgene Hyaluronan Synthase 2 of Naked Mole Rat in Oncolytic Gene Therapy

por Palomäki, Jussi, Kalke, Kiira, Orpana, Julius, Lund, Liisa, Frejborg, Fanny, Paavilainen, Henrik, Järveläinen, Hannu, Hukkanen, Veijo
Publicado 2023

The In Vitro Replication, Spread, and Oncolytic Potential of Finnish Circulating Strains of Herpes Simplex Virus Type 1

por Kalke, Kiira, Orpana, Julius, Lasanen, Tuomas, Esparta, Olaya, Lund, Liisa M., Frejborg, Fanny, Vuorinen, Tytti, Paavilainen, Henrik, Hukkanen, Veijo
Publicado 2022

Swarms of chemically modified antiviral siRNA targeting herpes simplex virus infection in human corneal epithelial cells

por Kalke, Kiira, Lund, Liisa M., Nyman, Marie C., Levanova, Alesia A., Urtti, Arto, Poranen, Minna M., Hukkanen, Veijo, Paavilainen, Henrik
Publicado 2022

Enzymatically synthesized 2′-fluoro-modified Dicer-substrate siRNA swarms against herpes simplex virus demonstrate enhanced antiviral efficacy and low cytotoxicity

por Levanova, Alesia A., Kalke, Kiira M., Lund, Liisa M., Sipari, Nina, Sadeghi, Mohammadreza, Nyman, Marie C., Paavilainen, Henrik, Hukkanen, Veijo, Poranen, Minna M.
Publicado 2020

Herpes Simplex Virus Type 1 Clinical Isolates Respond to UL29-Targeted siRNA Swarm Treatment Independent of Their Acyclovir Sensitivity

por Kalke, Kiira, Lehtinen, Jenni, Gnjatovic, Jelena, Lund, Liisa M., Nyman, Marie C., Paavilainen, Henrik, Orpana, Julius, Lasanen, Tuomas, Frejborg, Fanny, Levanova, Alesia A., Vuorinen, Tytti, Poranen, Minna M., Hukkanen, Veijo
Publicado 2020