Potent inhibitors of toxic alpha-synuclein identified via cellular time-resolved FRET biosensors

por Braun, Anthony R., Liao, Elly E., Horvath, Mian, Kalra, Prakriti, Acosta, Karen, Young, Malaney C., Kochen, Noah Nathan, Lo, Chih Hung, Brown, Roland, Evans, Michael D., Pomerantz, William C. K., Rhoades, Elizabeth, Luk, Kelvin, Cornea, Razvan L., Thomas, David D., Sachs, Jonathan N.
Publicado 2021

Controlling Intramolecular Interactions in the Design of Selective, High-Affinity Ligands for the CREBBP Bromodomain

por Brand, Michael, Clayton, James, Moroglu, Mustafa, Schiedel, Matthias, Picaud, Sarah, Bluck, Joseph P., Skwarska, Anna, Bolland, Hannah, Chan, Anthony K. N., Laurin, Corentine M. C., Scorah, Amy R., See, Larissa, Rooney, Timothy P. C., Andrews, Katrina H., Fedorov, Oleg, Perell, Gabriella, Kalra, Prakriti, Vinh, Kayla B., Cortopassi, Wilian A., Heitel, Pascal, Christensen, Kirsten E., Cooper, Richard I., Paton, Robert S., Pomerantz, William C. K., Biggin, Philip C., Hammond, Ester M., Filippakopoulos, Panagis, Conway, Stuart J.
Publicado 2021