The natural alkaloid Jerantinine B has activity in acute myeloid leukemia cells through a mechanism involving c-Jun

por Alhuthali, Hayaa Moeed, Bradshaw, Tracey D., Lim, Kuan-Hon, Kam, Toh-Seok, Seedhouse, Claire H.
Publicado 2020

Apoferritin-Encapsulated Jerantinine A for Transferrin Receptor Targeting and Enhanced Selectivity in Breast Cancer Therapy

por Abuzaid, Haneen, Abdelrazig, Salah, Ferreira, Lenny, Collins, Hilary M., Kim, Dong-Hyun, Lim, Kuan-Hon, Kam, Toh-Seok, Turyanska, Lyudmila, Bradshaw, Tracey D.
Publicado 2022

Sustainable Syntheses of (−)-Jerantinines A & E and Structural Characterisation of the Jerantinine-Tubulin Complex at the Colchicine Binding Site

por Smedley, Christopher J., Stanley, Paul A., Qazzaz, Mohannad E., Prota, Andrea E., Olieric, Natacha, Collins, Hilary, Eastman, Harry, Barrow, Andrew S., Lim, Kuan-Hon, Kam, Toh-Seok, Smith, Brian J., Duivenvoorden, Hendrika M., Parker, Belinda S., Bradshaw, Tracey D., Steinmetz, Michel O., Moses, John E.
Publicado 2018

Jerantinine A induces tumor-specific cell death through modulation of splicing factor 3b subunit 1 (SF3B1)

por Chung, Felicia Fei-Lei, Tan, Perry Faith Tze Ming, Raja, Vijay Joseph, Tan, Boon-Shing, Lim, Kuan-Hon, Kam, Toh-Seok, Hii, Ling-Wei, Tan, Si Hoey, See, Sze-Jia, Tan, Yuen-Fen, Wong, Li-Zhe, Yam, Wai Keat, Mai, Chun Wai, Bradshaw, Tracey D., Leong, Chee-Onn
Publicado 2017