Synaptic Vesicle Glycoprotein 2A Ligands in the Treatment of Epilepsy and Beyond

por Löscher, Wolfgang, Gillard, Michel, Sands, Zara A., Kaminski, Rafal M., Klitgaard, Henrik
Publicado 2016

Inhibiting Epileptiform Activity in Cognitive Disorders: Possibilities for a Novel Therapeutic Approach

por Horvath, Andras Attila, Csernus, Emoke Anna, Lality, Sara, Kaminski, Rafal M., Kamondi, Anita
Publicado 2020

Functional characterization of the antiepileptic drug candidate, padsevonil, on GABA(A) receptors

por Niespodziany, Isabelle, Ghisdal, Philippe, Mullier, Brice, Wood, Martyn, Provins, Laurent, Kaminski, Rafal M., Wolff, Christian
Publicado 2020

The Search for New Anticonvulsants in a Group of (2,5-Dioxopyrrolidin-1-yl)(phenyl)Acetamides with Hybrid Structure—Synthesis and In Vivo/In Vitro Studies

por Abram, Michał, Jakubiec, Marcin, Rapacz, Anna, Mogilski, Szczepan, Latacz, Gniewomir, Kamiński, Rafał M., Kamiński, Krzysztof
Publicado 2020

Effects of Cocaine-Kindling on the Expression of NMDA Receptors and Glutamate Levels in Mouse Brain

por Kaminski, Rafal M., Núñez-Taltavull, Juan F., Budziszewska, Bogusława, Lasoń, Władysław, Gasior, Maciej, Zapata, Agustin, Shippenberg, Toni S., Witkin, Jeffrey M.
Publicado 2010

Radiprodil, a NR2B negative allosteric modulator, from bench to bedside in infantile spasm syndrome

por Auvin, Stéphane, Dozières‐Puyravel, Blandine, Avbersek, Andreja, Sciberras, David, Collier, Jo, Leclercq, Karine, Mares, Pavel, Kaminski, Rafal M., Muglia, Pierandrea
Publicado 2020

Connectivity Mapping Using a Novel sv2a Loss-of-Function Zebrafish Epilepsy Model as a Powerful Strategy for Anti-epileptic Drug Discovery

por Zhang, Yifan, Heylen, Lise, Partoens, Michèle, Mills, James D., Kaminski, Rafal M., Godard, Patrice, Gillard, Michel, de Witte, Peter A. M., Siekierska, Aleksandra
Publicado 2022

Inhibition of glutamate decarboxylase (GAD) by ethyl ketopentenoate (EKP) induces treatment-resistant epileptic seizures in zebrafish

por Zhang, Yifan, Vanmeert, Michiel, Siekierska, Aleksandra, Ny, Annelii, John, Jubi, Callewaert, Geert, Lescrinier, Eveline, Dehaen, Wim, de Witte, Peter A. M., Kaminski, Rafal M.
Publicado 2017

Translocator protein PET imaging in temporal lobe epilepsy: A reliable test-retest study using asymmetry index

por Mahmud, Mohammad, Wade, Charles, Jawad, Sarah, Hadi, Zaeem, Otoul, Christian, Kaminski, Rafal M., Muglia, Pierandrea, Kadiu, Irena, Rabiner, Eugenii, Maguire, Paul, Owen, David R., Johnson, Michael R.
Publicado 2023

Identification of New Compounds with Anticonvulsant and Antinociceptive Properties in a Group of 3-substituted (2,5-dioxo-pyrrolidin-1-yl)(phenyl)-Acetamides

por Abram, Michał, Jakubiec, Marcin, Rapacz, Anna, Mogilski, Szczepan, Latacz, Gniewomir, Szulczyk, Bartłomiej, Szafarz, Małgorzata, Socała, Katarzyna, Nieoczym, Dorota, Wyska, Elżbieta, Wlaź, Piotr, Kamiński, Rafał M., Kamiński, Krzysztof
Publicado 2021

Different MicroRNA Profiles in Chronic Epilepsy Versus Acute Seizure Mouse Models

por Kretschmann, Anita, Danis, Benedicte, Andonovic, Lidija, Abnaof, Khalid, van Rikxoort, Marijke, Siegel, Franziska, Mazzuferi, Manuela, Godard, Patrice, Hanon, Etienne, Fröhlich, Holger, Kaminski, Rafal M., Foerch, Patrik, Pfeifer, Alexander
Publicado 2014

Intrinsic Inflammation Is a Potential Anti-Epileptogenic Target in the Organotypic Hippocampal Slice Model

por Chong, Seon-Ah, Balosso, Silvia, Vandenplas, Catherine, Szczesny, Gregory, Hanon, Etienne, Claes, Kasper, Van Damme, Xavier, Danis, Bénédicte, Van Eyll, Jonathan, Wolff, Christian, Vezzani, Annamaria, Kaminski, Rafal M., Niespodziany, Isabelle
Publicado 2018

New Phenylglycinamide Derivatives with Hybrid Structure as Candidates for New Broad-Spectrum Anticonvulsants

por Jakubiec, Marcin, Abram, Michał, Zagaja, Mirosław, Andres-Mach, Marta, Szewczyk, Aleksandra, Latacz, Gniewomir, Szulczyk, Bartłomiej, Socała, Katarzyna, Nieoczym, Dorota, Wlaź, Piotr, Metcalf, Cameron S., Wilcox, Karen, Kamiński, Rafał M., Kamiński, Krzysztof
Publicado 2022

Differential expression of miR-184 in temporal lobe epilepsy patients with and without hippocampal sclerosis – Influence on microglial function

por Danis, Bénédicte, van Rikxoort, Marijke, Kretschmann, Anita, Zhang, Jiong, Godard, Patrice, Andonovic, Lidija, Siegel, Franziska, Niehusmann, Pitt, Hanon, Etienne, Delev, Daniel, von Lehe, Marec, Kaminski, Rafal M., Pfeifer, Alexander, Foerch, Patrik
Publicado 2016

Implication of sestrin3 in epilepsy and its comorbidities

por Lovisari, Francesca, Roncon, Paolo, Soukoupova, Marie, Paolone, Giovanna, Labasque, Marilyne, Ingusci, Selene, Falcicchia, Chiara, Marino, Pietro, Johnson, Michael, Rossetti, Tiziana, Petretto, Enrico, Leclercq, Karine, Kaminski, Rafal M, Moyon, Ben, Webster, Zoe, Simonato, Michele, Zucchini, Silvia
Publicado 2020

Rare and common epilepsies converge on a shared gene regulatory network providing opportunities for novel antiepileptic drug discovery

por Delahaye-Duriez, Andree, Srivastava, Prashant, Shkura, Kirill, Langley, Sarah R., Laaniste, Liisi, Moreno-Moral, Aida, Danis, Bénédicte, Mazzuferi, Manuela, Foerch, Patrik, Gazina, Elena V., Richards, Kay, Petrou, Steven, Kaminski, Rafal M., Petretto, Enrico, Johnson, Michael R.
Publicado 2016

Genome-wide analysis of differential RNA editing in epilepsy

por Srivastava, Prashant Kumar, Bagnati, Marta, Delahaye-Duriez, Andree, Ko, Jeong-Hun, Rotival, Maxime, Langley, Sarah R., Shkura, Kirill, Mazzuferi, Manuela, Danis, Bénédicte, van Eyll, Jonathan, Foerch, Patrik, Behmoaras, Jacques, Kaminski, Rafal M., Petretto, Enrico, Johnson, Michael R.
Publicado 2017

Padsevonil randomized Phase IIa trial in treatment-resistant focal epilepsy: a translational approach

por Muglia, Pierandrea, Hannestad, Jonas, Brandt, Christian, DeBruyn, Steven, Germani, Massimiliano, Lacroix, Brigitte, Majoie, Marian, Otoul, Christian, Sciberras, David, Steinhoff, Bernhard J, Van Laere, Koen, Van Paesschen, Wim, Webster, Elizabeth, Kaminski, Rafal M, Werhahn, Konrad J, Toledo, Manuel
Publicado 2020

n-3 Docosapentaenoic acid-derived protectin D1 promotes resolution of neuroinflammation and arrests epileptogenesis

por Frigerio, Federica, Pasqualini, Giulia, Craparotta, Ilaria, Marchini, Sergio, van Vliet, Erwin A, Foerch, Patrick, Vandenplas, Catherine, Leclercq, Karin, Aronica, Eleonora, Porcu, Luca, Pistorius, Kimberly, Colas, Romain A, Hansen, Trond V, Perretti, Mauro, Kaminski, Rafal M, Dalli, Jesmond, Vezzani, Annamaria
Publicado 2018

A single‐center, open‐label positron emission tomography study to evaluate brivaracetam and levetiracetam synaptic vesicle glycoprotein 2A binding in healthy volunteers

por Finnema, Sjoerd J., Rossano, Samantha, Naganawa, Mika, Henry, Shannan, Gao, Hong, Pracitto, Richard, Maguire, Ralph P., Mercier, Joël, Kervyn, Sophie, Nicolas, Jean‐Marie, Klitgaard, Henrik, DeBruyn, Steven, Otoul, Christian, Martin, Paul, Muglia, Pierandrea, Matuskey, David, Nabulsi, Nabeel B., Huang, Yiyun, Kaminski, Rafal M., Hannestad, Jonas, Stockis, Armel, Carson, Richard E.
Publicado 2019