Mutant TP53 driving the Warburg Effect in Mantle Cell lymphoma

por Kliebhan, Johannes, Besse, Andrej, Kampa‐Schittenhelm, Kerstin, Schittenhelm, Marcus, Driessen, Christoph
Publicado 2022

Quizartinib (AC220) is a potent second generation class III tyrosine kinase inhibitor that displays a distinct inhibition profile against mutant-FLT3, -PDGFRA and -KIT isoforms

por Kampa-Schittenhelm, Kerstin Maria, Heinrich, Michael Charles, Akmut, Figen, Döhner, Hartmut, Döhner, Konstanze, Schittenhelm, Marcus Matthias
Publicado 2013

Dronabinol has preferential antileukemic activity in acute lymphoblastic and myeloid leukemia with lymphoid differentiation patterns

por Kampa-Schittenhelm, Kerstin Maria, Salitzky, Olaf, Akmut, Figen, Illing, Barbara, Kanz, Lothar, Salih, Helmut Rainer, Schittenhelm, Marcus Matthias
Publicado 2016

ASPP2κ Is Expressed In Human Colorectal Carcinoma And Promotes Chemotherapy Resistance And Tumorigenesis

por Rieger, Ingmar, Tsintari, Vasileia, Overkamp, Mathis, Fend, Falko, Lopez, Charles D., Schittenhelm, Marcus M., Kampa-Schittenhelm, Kerstin M.
Publicado 2021

Crenolanib is a type I tyrosine kinase inhibitor that inhibits mutant KIT D816 isoforms prevalent in systemic mastocytosis and core binding factor leukemia

por Kampa-Schittenhelm, Kerstin Maria, Frey, Julia, Haeusser, Lara A., Illing, Barbara, Pavlovsky, Ashly A., Blumenstock, Gunnar, Schittenhelm, Marcus Matthias
Publicado 2017

Dasatinib overrides the differentiation blockage in a patient with mutant-KIT D816V positive CBFβ-MYH11 leukemia

por Kampa-Schittenhelm, Kerstin M., Vogel, Wichard, Bonzheim, Irina, Fend, Falko, Horger, Marius, Kanz, Lothar, Soekler, Martin, Schittenhelm, Marcus M.
Publicado 2018

Alternative splicing of Apoptosis Stimulating Protein of TP53-2 (ASPP2) results in an oncogenic isoform promoting migration and therapy resistance in soft tissue sarcoma (STS)

por Tsintari, Vasileia, Walter, Bianca, Fend, Falko, Overkamp, Mathis, Rothermundt, Christian, Lopez, Charles D., Schittenhelm, Marcus M., Kampa-Schittenhelm, Kerstin M.
Publicado 2022

Cell cycle-dependent activity of the novel dual PI3K-MTORC1/2 inhibitor NVP-BGT226 in acute leukemia

por Kampa-Schittenhelm, Kerstin Maria, Heinrich, Michael Charles, Akmut, Figen, Rasp, Katharina Henriette, Illing, Barbara, Döhner, Hartmut, Döhner, Konstanze, Schittenhelm, Marcus Matthias
Publicado 2013

Attenuated Expression of Apoptosis Stimulating Protein of p53-2 (ASPP2) in Human Acute Leukemia Is Associated with Therapy Failure

por Schittenhelm, Marcus M., Illing, Barbara, Ahmut, Figen, Rasp, Katharina Henriette, Blumenstock, Gunnar, Döhner, Konstanze, Lopez, Charles D., Kampa-Schittenhelm, Kerstin M.
Publicado 2013

Alternative splicing of the tumor suppressor ASPP2 results in a stress-inducible, oncogenic isoform prevalent in acute leukemia

por Schittenhelm, Marcus Matthias, Walter, Bianca, Tsintari, Vasileia, Federmann, Birgit, Bajrami Saipi, Mihada, Akmut, Figen, Illing, Barbara, Mau-Holzmann, Ulrike, Fend, Falko, Lopez, Charles Darin, Kampa-Schittenhelm, Kerstin Maria
Publicado 2019