Validation of a multiplexed and targeted lipidomics assay for accurate quantification of lipidomes

por Zhang, Nanyan Rena, Hatcher, Nathan G., Ekroos, Kim, Kedia, Komal, Kandebo, Monika, Marcus, Jacob N., Smith, Sean M., Bateman, Kevin P., Spellman, Daniel S.
Publicado 2022

Decreased glucocerebrosidase activity and substrate accumulation of glycosphingolipids in a novel GBA1 D409V knock-in mouse model

por Polinski, Nicole K., Martinez, Terina N., Gorodinsky, Alexander, Gareus, Ralph, Sasner, Michael, Herberth, Mark, Switzer, Robert, Ahmad, Syed O., Cosden, Mali, Kandebo, Monika, Drolet, Robert E., Buckett, Peter D., Shan, Weisong, Chen, Yi, Pellegrino, Lee J., Ellsworth, Gregory D., Dungan, Leo B., Hirst, Warren D., Clark, Sean W., Dave, Kuldip D.
Publicado 2021

Discovery of MK-8189, a Highly Potent and Selective PDE10A Inhibitor for the Treatment of Schizophrenia

por Layton, Mark E., Kern, Jeffrey C., Hartingh, Timothy J., Shipe, William D., Raheem, Izzat, Kandebo, Monika, Hayes, Robert P., Huszar, Sarah, Eddins, Donnie, Ma, Bennett, Fuerst, Joy, Wollenberg, Gordon K., Li, Jing, Fritzen, Jeff, McGaughey, Georgia B., Uslaner, Jason M., Smith, Sean M., Coleman, Paul J., Cox, Christopher D.
Publicado 2023