Inhibition of cancer-type amino acid transporter LAT1 suppresses B16-F10 melanoma metastasis in mouse models

por Shi, Zitong, Kaneda-Nakashima, Kazuko, Ohgaki, Ryuichi, Xu, Minhui, Okanishi, Hiroki, Endou, Hitoshi, Nagamori, Shushi, Kanai, Yoshikatsu
Publicado 2023

Effect to Therapy of Sodium-Iodine Symporter Expression by Alpha-Ray Therapeutic Agent via Sodium/Iodine Symporter

por Kaneda-Nakashima, Kazuko, Shirakami, Yoshifumi, Watabe, Tadashi, Ooe, Kazuhiro, Yoshimura, Takashi, Toyoshima, Atsushi, Wang, Yang, Haba, Hiromitsu, Fukase, Koichi
Publicado 2022

Enhancement of (211)At Uptake via the Sodium Iodide Symporter by the Addition of Ascorbic Acid in Targeted α-Therapy of Thyroid Cancer

por Watabe, Tadashi, Kaneda-Nakashima, Kazuko, Liu, Yuwei, Shirakami, Yoshifumi, Ooe, Kazuhiro, Toyoshima, Atsushi, Shimosegawa, Eku, Fukuda, Mitsuhiro, Shinohara, Atsushi, Hatazawa, Jun
Publicado 2019

Preclinical Evaluation of Radiation-Induced Toxicity in Targeted Alpha Therapy Using [(211)At] NaAt in Mice: A Revisit()

por Liu, Yuwei, Watabe, Tadashi, Kaneda-Nakashima, Kazuko, Ooe, Kazuhiro, Shirakami, Yoshifumi, Toyoshima, Atsushi, Shimosegawa, Eku, Nakano, Takashi, Shinohara, Atsushi, Hatazawa, Jun
Publicado 2020

Mathematical Model for Evaluation of Tumor Response in Targeted Radionuclide Therapy with (211)At Using Implanted Mouse Tumor

por Yonekura, Yoshiharu, Toki, Hiroshi, Watabe, Tadashi, Kaneda-Nakashima, Kazuko, Shirakami, Yoshifumi, Ooe, Kazuhiro, Toyoshima, Atsushi, Nakajima, Hiroo, Tomiyama, Noriyuki, Bando, Masako
Publicado 2022

Targeted alpha therapy using astatine ((211)At)-labeled phenylalanine: A preclinical study in glioma bearing mice

por Watabe, Tadashi, Kaneda-Nakashima, Kazuko, Shirakami, Yoshifumi, Liu, Yuwei, Ooe, Kazuhiro, Teramoto, Takahiro, Toyoshima, Atsushi, Shimosegawa, Eku, Nakano, Takashi, Kanai, Yoshikatsu, Shinohara, Atsushi, Hatazawa, Jun
Publicado 2020

Astatine-211-Labeled Gold Nanoparticles for Targeted Alpha-Particle Therapy via Intravenous Injection

por Huang, Xuhao, Kaneda-Nakashima, Kazuko, Kadonaga, Yuichiro, Kabayama, Kazuya, Shimoyama, Atsushi, Ooe, Kazuhiro, Kato, Hiroki, Toyoshima, Atsushi, Shinohara, Atsushi, Haba, Hiromitsu, Wang, Yang, Fukase, Koichi
Publicado 2022

Suppression of GPR56 expression by pyrrole-imidazole polyamide represents a novel therapeutic drug for AML with high EVI1 expression

por Saha, Hasi Rani, Kaneda-Nakashima, Kazuko, Shimosaki, Shunsuke, Suekane, Akira, Sarkar, Bidhan, Saito, Yusuke, Ogoh, Honami, Nakahata, Shingo, Inoue, Kentaro, Watanabe, Takayoshi, Nagase, Hiroki, Morishita, Kazuhiro
Publicado 2018

Targeted α-therapy using astatine ((211)At)-labeled PSMA1, 5, and 6: a preclinical evaluation as a novel compound

por Watabe, Tadashi, Kaneda-Nakashima, Kazuko, Shirakami, Yoshifumi, Kadonaga, Yuichiro, Ooe, Kazuhiro, Wang, Yang, Haba, Hiromitsu, Toyoshima, Atsushi, Cardinale, Jens, Giesel, Frederik L., Tomiyama, Noriyuki, Fukase, Koichi
Publicado 2022

Extended single-dose toxicity study of [(211)At]NaAt in mice for the first-in-human clinical trial of targeted alpha therapy for differentiated thyroid cancer

por Watabe, Tadashi, Kaneda-Nakashima, Kazuko, Ooe, Kazuhiro, Liu, Yuwei, Kurimoto, Kenta, Murai, Takashi, Shidahara, Yuka, Okuma, Kenji, Takeuchi, Masanori, Nishide, Masayuki, Toyoshima, Atsushi, Shinohara, Atsushi, Shirakami, Yoshifumi
Publicado 2021

Fibroblast activation protein targeted therapy using [(177)Lu]FAPI-46 compared with [(225)Ac]FAPI-46 in a pancreatic cancer model

por Liu, Yuwei, Watabe, Tadashi, Kaneda-Nakashima, Kazuko, Shirakami, Yoshifumi, Naka, Sadahiro, Ooe, Kazuhiro, Toyoshima, Atsushi, Nagata, Kojiro, Haberkorn, Uwe, Kratochwil, Clemens, Shinohara, Atsushi, Hatazawa, Jun, Giesel, Frederik
Publicado 2021

Comparison of the Therapeutic Effects of [(211)At]NaAt and [(131)I]NaI in an NIS-Expressing Thyroid Cancer Mouse Model

por Watabe, Tadashi, Liu, Yuwei, Kaneda-Nakashima, Kazuko, Sato, Tatsuhiko, Shirakami, Yoshifumi, Ooe, Kazuhiro, Toyoshima, Atsushi, Shimosegawa, Eku, Wang, Yang, Haba, Hiromitsu, Nakano, Takashi, Shinohara, Atsushi, Hatazawa, Jun
Publicado 2022

α‐Emitting cancer therapy using (211)At‐AAMT targeting LAT1

por Kaneda‐Nakashima, Kazuko, Zhang, ZiJian, Manabe, Yoshiyuki, Shimoyama, Atsushi, Kabayama, Kazuya, Watabe, Tadashi, Kanai, Yoshikatsu, Ooe, Kazuhiro, Toyoshima, Atsushi, Shirakami, Yoshifumi, Yoshimura, Takashi, Fukuda, Mitsuhiro, Hatazawa, Jun, Nakano, Takashi, Fukase, Koichi, Shinohara, Atsushi
Publicado 2021

Evaluation of Astatine-211-Labeled Fibroblast Activation Protein Inhibitor (FAPI): Comparison of Different Linkers with Polyethylene Glycol and Piperazine

por Aso, Ayaka, Nabetani, Hinako, Matsuura, Yoshifumi, Kadonaga, Yuichiro, Shirakami, Yoshifumi, Watabe, Tadashi, Yoshiya, Taku, Mochizuki, Masayoshi, Ooe, Kazuhiro, Kawakami, Atsuko, Jinno, Naoya, Toyoshima, Atsushi, Haba, Hiromitsu, Wang, Yang, Cardinale, Jens, Giesel, Frederik Lars, Shimoyama, Atsushi, Kaneda-Nakashima, Kazuko, Fukase, Koichi
Publicado 2023