Chemically oligomerizable TDP-43: a novel chemogenetic tool for studying the pathophysiology of amyotrophic lateral sclerosis

por Kanekura, Kohsuke, Yamanaka, Yoshiaki, Miyagi, Tamami, Kuroda, Masahiko
Publicado 2022

Effect of Multivalency on Phase-Separated Droplets Consisting of Poly(PR) Dipeptide Repeats and RNA at the Solid/Liquid Interface

por Chen, Chen, Jia, Han, Nakamura, Yoshiki, Kanekura, Kohsuke, Hayamizu, Yuhei
Publicado 2022

Characterization of membrane penetration and cytotoxicity of C9orf72-encoding arginine-rich dipeptides

por Kanekura, Kohsuke, Harada, Yuichiro, Fujimoto, Mao, Yagi, Takuya, Hayamizu, Yuhei, Nagaoka, Kentaro, Kuroda, Masahiko
Publicado 2018

Neuroplastin Modulates Anti-inflammatory Effects of MANF

por Yagi, Takuya, Asada, Rie, Kanekura, Kohsuke, Eesmaa, Ave, Lindahl, Maria, Saarma, Mart, Urano, Fumihiko
Publicado 2020

A soluble endoplasmic reticulum factor as regenerative therapy for Wolfram syndrome

por Mahadevan, Jana, Morikawa, Shuntaro, Yagi, Takuya, Abreu, Damien, Lu, Simin, Kanekura, Kohsuke, Brown, Cris M., Urano, Fumihiko
Publicado 2020

The Patterning and Proportion of Charged Residues in the Arginine-Rich Mixed-Charge Domain Determine the Membrane-Less Organelle Targeted by the Protein

por Miyagi, Tamami, Yamazaki, Rio, Ueda, Koji, Narumi, Satoshi, Hayamizu, Yuhei, Uji-i, Hiroshi, Kuroda, Masahiko, Kanekura, Kohsuke
Publicado 2022

Acerola exosome-like nanovesicles to systemically deliver nucleic acid medicine via oral administration

por Umezu, Tomohiro, Takanashi, Masakatsu, Murakami, Yoshiki, Ohno, Shin-ichiro, Kanekura, Kohsuke, Sudo, Katsuko, Nagamine, Kenichi, Takeuchi, Shin, Ochiya, Takahiro, Kuroda, Masahiko
Publicado 2021

Neuroimaging evidence of deficient axon myelination in Wolfram syndrome

por Lugar, Heather M., Koller, Jonathan M., Rutlin, Jerrel, Marshall, Bess A., Kanekura, Kohsuke, Urano, Fumihiko, Bischoff, Allison N., Shimony, Joshua S., Hershey, Tamara
Publicado 2016

A Novel Homozygous Mutation of Thyroid Peroxidase Gene Abolishes a Disulfide Bond Leading to Congenital Hypothyroidism

por Yakou, Fumiyoshi, Suwanai, Hirotsugu, Ishikawa, Takuya, Itou, Mariko, Shikuma, Jumpei, Miwa, Takashi, Sakai, Hiroyuki, Kanekura, Kohsuke, Narumi, Satoshi, Suzuki, Ryo, Odawara, Masato
Publicado 2020

Differential toxicity and localization of arginine-rich C9ORF72 dipeptide repeat proteins depend on de-clustering of positive charges

por Miyagi, Tamami, Ueda, Koji, Sugimoto, Masahiro, Yagi, Takuya, Ito, Daisuke, Yamazaki, Rio, Narumi, Satoshi, Hayamizu, Yuhei, Uji-i, Hiroshi, Kuroda, Masahiko, Kanekura, Kohsuke
Publicado 2023

Comprehensive analysis of liver and blood miRNA in precancerous conditions

por Umezu, Tomohiro, Tsuneyama, Koichi, Kanekura, Kohsuke, Hayakawa, Michiyo, Tanahashi, Toshihito, Kawano, Mitsuoki, Taguchi, Y-h, Toyoda, Hidenori, Tamori, Akihiro, Kuroda, Masahiko, Murakami, Yoshiki
Publicado 2020

Targeting Cellular Calcium Homeostasis to Prevent Cytokine-Mediated Beta Cell Death

por Clark, Amy L., Kanekura, Kohsuke, Lavagnino, Zeno, Spears, Larry D., Abreu, Damien, Mahadevan, Jana, Yagi, Takuya, Semenkovich, Clay F., Piston, David W., Urano, Fumihiko
Publicado 2017

Phase separation and toxicity of C9orf72 poly(PR) depends on alternate distribution of arginine

por Chen, Chen, Yamanaka, Yoshiaki, Ueda, Koji, Li, Peiying, Miyagi, Tamami, Harada, Yuichiro, Tezuka, Sayaka, Narumi, Satoshi, Sugimoto, Masahiro, Kuroda, Masahiko, Hayamizu, Yuhei, Kanekura, Kohsuke
Publicado 2021

Expression of L-type amino acid transporter 1 is a poor prognostic factor for Non-Hodgkin’s lymphoma

por Jigjidkhorloo, Narangerel, Kanekura, Kohsuke, Matsubayashi, Jun, Akahane, Daigo, Fujita, Koji, Oikawa, Keiki, Kurata, Atsushi, Takanashi, Masakatsu, Endou, Hitoshi, Nagao, Toshitaka, Gotoh, Akihiko, Norov, Oyundelger, Kuroda, Masahiko
Publicado 2021

Pathological processes in aqueous humor due to iris atrophy predispose to early corneal graft failure in humans and mice

por Yamaguchi, Takefumi, Higa, Kazunari, Yagi-Yaguchi, Yukari, Ueda, Koji, Noma, Hisashi, Shibata, Shinsuke, Nagai, Toshihiro, Tomida, Daisuke, Yasu-Mimura, Ririko, Ibrahim, Osama, Matoba, Ryo, Tsubota, Kazuo, Hamrah, Pedram, Yamada, Jun, Kanekura, Kohsuke, Shimazaki, Jun
Publicado 2020