Engineering Smart Targeting Nanovesicles and Their Combination with Hydrogels for Controlled Drug Delivery

por Elkhoury, Kamil, Koçak, Polen, Kang, Alex, Arab-Tehrany, Elmira, Ellis Ward, Jennifer, Shin, Su Ryon
Publicado 2020

Point of Care Measurement of Body Mass Index and Thyroid Nodule Malignancy Risk Assessment

por Ahmadi, Sara, Pappa, Theodora, Kang, Alex S., Coleman, Alexandra K., Landa, Iñigo, Marqusee, Ellen, Kim, Matthew, Angell, Trevor E., Alexander, Erik K.
Publicado 2022

Clinical experience following implementation of routine SPECT-CT imaging following 131-iodine administration for thyroid cancer

por Ahmadi, Sara, Coleman, Alexandra, de Morais, Nathalie Silva, Landa, Iñigo, Pappa, Theodora, Kang, Alex, Kim, Matthew I, Marqusee, Ellen, Alexander, Erik K
Publicado 2022

p53 plays a central role in the development of osteoporosis

por Yu, Tao, You, Xiaomeng, Zhou, Haichao, Kang, Alex, He, Wenbao, Li, Zihua, Li, Bing, Xia, Jiang, Zhu, Hui, Zhao, Youguang, Yu, Guangrong, Xiong, Yuan, Yang, Yunfeng
Publicado 2020

De novo design of protein homodimers containing tunable symmetric protein pockets

por Hicks, Derrick R., Kennedy, Madison A., Thompson, Kirsten A., DeWitt, Michelle, Coventry, Brian, Kang, Alex, Bera, Asim K., Brunette, T. J., Sankaran, Banumathi, Stoddard, Barry, Baker, David
Publicado 2022

Hallucination of closed repeat proteins containing central pockets

por An, Linna, Hicks, Derrick R., Zorine, Dmitri, Dauparas, Justas, Wicky, Basile I. M., Milles, Lukas F., Courbet, Alexis, Bera, Asim K., Nguyen, Hannah, Kang, Alex, Carter, Lauren, Baker, David
Publicado 2023

Design of Diverse Asymmetric Pockets in De Novo Homo-oligomeric Proteins

por Gerben, Stacey R, Borst, Andrew J, Hicks, Derrick R, Moczygemba, Isabelle, Feldman, David, Coventry, Brian, Yang, Wei, Bera, Asim K., Miranda, Marcos, Kang, Alex, Nguyen, Hannah, Baker, David
Publicado 2023

Cyclic peptide structure prediction and design using AlphaFold

por Rettie, Stephen A., Campbell, Katelyn V., Bera, Asim K., Kang, Alex, Kozlov, Simon, De La Cruz, Joshmyn, Adebomi, Victor, Zhou, Guangfeng, DiMaio, Frank, Ovchinnikov, Sergey, Bhardwaj, Gaurav
Publicado 2023

De novo design of monomeric helical bundles for pH‐controlled membrane lysis

por Goldbach, Nicolas, Benna, Issa, Wicky, Basile I. M., Croft, Jacob T., Carter, Lauren, Bera, Asim K., Nguyen, Hannah, Kang, Alex, Sankaran, Banumathi, Yang, Erin C., Lee, Kelly K., Baker, David
Publicado 2023

Rapamycin rejuvenates oral health in aging mice

por An, Jonathan Y, Kerns, Kristopher A, Ouellette, Andrew, Robinson, Laura, Morris, H Douglas, Kaczorowski, Catherine, Park, So-Il, Mekvanich, Title, Kang, Alex, McLean, Jeffrey S, Cox, Timothy C, Kaeberlein, Matt
Publicado 2020

Exploration of Structured Symmetric Cyclic Peptides as Ligands for Metal-Organic Frameworks

por Said, Meerit Y., Kang, Christine S., Wang, Shunzhi, Sheffler, William, Salveson, Patrick J., Bera, Asim K., Kang, Alex, Nguyen, Hannah, Ballard, Ryanne, Li, Xinting, Bai, Hua, Stewart, Lance, Levine, Paul, Baker, David
Publicado 2022

Computational design of a synthetic PD-1 agonist

por Bryan, Cassie M., Rocklin, Gabriel J., Bick, Matthew J., Ford, Alex, Majri-Morrison, Sonia, Kroll, Ashley V., Miller, Chad J., Carter, Lauren, Goreshnik, Inna, Kang, Alex, DiMaio, Frank, Tarbell, Kristin V., Baker, David
Publicado 2021

Reconfigurable asymmetric protein assemblies through implicit negative design

por Sahtoe, Danny D., Praetorius, Florian, Courbet, Alexis, Hsia, Yang, Wicky, Basile I.M., Edman, Natasha I., Miller, Lauren M., Timmermans, Bart J. R., Decarreau, Justin, Morris, Hana M., Kang, Alex, Bera, Asim K., Baker, David
Publicado 2022

Precisely patterned nanofibres made from extendable protein multiplexes

por Bethel, Neville P., Borst, Andrew J., Parmeggiani, Fabio, Bick, Matthew J., Brunette, TJ, Nguyen, Hannah, Kang, Alex, Bera, Asim K., Carter, Lauren, Miranda, Marcos C., Kibler, Ryan D., Lamb, Mila, Li, Xinting, Sankaran, Banumathi, Baker, David
Publicado 2023

De novo design of small beta barrel proteins

por Kim, David E., Jensen, Davin R., Feldman, David, Tischer, Doug, Saleem, Ayesha, Chow, Cameron M., Li, Xinting, Carter, Lauren, Milles, Lukas, Nguyen, Hannah, Kang, Alex, Bera, Asim K., Peterson, Francis C., Volkman, Brian F., Ovchinnikov, Sergey, Baker, David
Publicado 2023

Design of multi-scale protein complexes by hierarchical building block fusion

por Hsia, Yang, Mout, Rubul, Sheffler, William, Edman, Natasha I., Vulovic, Ivan, Park, Young-Jun, Redler, Rachel L., Bick, Matthew J., Bera, Asim K., Courbet, Alexis, Kang, Alex, Brunette, T. J., Nattermann, Una, Tsai, Evelyn, Saleem, Ayesha, Chow, Cameron M., Ekiert, Damian, Bhabha, Gira, Veesler, David, Baker, David
Publicado 2021

Design of stimulus-responsive two-state hinge proteins

por Praetorius, Florian, Leung, Philip J. Y., Tessmer, Maxx H., Broerman, Adam, Demakis, Cullen, Dishman, Acacia F., Pillai, Arvind, Idris, Abbas, Juergens, David, Dauparas, Justas, Li, Xinting, Levine, Paul M., Lamb, Mila, Ballard, Ryanne K., Gerben, Stacey R., Nguyen, Hannah, Kang, Alex, Sankaran, Banumathi, Bera, Asim K., Volkman, Brian F., Nivala, Jeff, Stoll, Stefan, Baker, David
Publicado 2023

Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains

por Wang, Jing Yang (John), Khmelinskaia, Alena, Sheffler, William, Miranda, Marcos C., Antanasijevic, Aleksandar, Borst, Andrew J., Torres, Susana V., Shu, Chelsea, Hsia, Yang, Nattermann, Una, Ellis, Daniel, Walkey, Carl, Ahlrichs, Maggie, Chan, Sidney, Kang, Alex, Nguyen, Hannah, Sydeman, Claire, Sankaran, Banumathi, Wu, Mengyu, Bera, Asim K., Carter, Lauren, Fiala, Brooke, Murphy, Michael, Baker, David, Ward, Andrew B., King, Neil P.
Publicado 2023

De novo design of energy transfer proteins housing excitonically coupled chlorophyll special pairs

por Ennist, Nathan, Wang, Shunzhi, Kennedy, Madison, Curti, Mariano, Sutherland, George, Vasilev, Cvetelin, Redler, Rachel, Maffeis, Valentin, Shareef, Saeed, Sica, Anthony, Hua, Ash, Deshmukh, Arundhati, Moyer, Adam, Hicks, Derrick, Swartz, Avi, Cacho, Ralph, Novy, Nathan, Bera, Asim, Kang, Alex, Sankaran, Banumathi, Johnson, Matthew, Reppert, Mike, Ekiert, Damian, Bhabha, Gira, Stewart, Lance, Caram, Justin, Stoddard, Barry, Romero, Elisabet, Hunter, C. Neil, Baker, David
Publicado 2023