Delta-secretase cleavage of Tau mediates its pathology and propagation in Alzheimer’s disease

por Kang, Seong Su, Ahn, Eun Hee, Ye, Keqiang
Publicado 2020

Altered Regulation of Type II 11β-hydroxysteroid Dehydrogenase in the Kidney of Rats with Experimental Hypertension

por Kang, Seong Su, Kim, Soo Wan, Lee, JongUn
Publicado 2007

Inhibition of a novel specific neuroglial integrin signaling pathway increases STAT3-mediated CNTF expression

por Keasey, Matthew P, Kang, Seong Su, Lovins, Chiharu, Hagg, Theo
Publicado 2013

Gut dysbiosis contributes to amyloid pathology, associated with C/EBPβ/AEP signaling activation in Alzheimer’s disease mouse model

por Chen, Chun, Ahn, Eun Hee, Kang, Seong Su, Liu, Xia, Alam, Ashfaqul, Ye, Keqiang
Publicado 2020

Co-amplification of Phosphoinositide 3-kinase enhancer A and Cyclin-dependent kinase 4 Triggers Glioblastoma Progression

por Qi, Qi, Kang, Seong-Su, Zhang, Shuai, Pham, Cau, Fu, Haian, Brat, Daniel J., Ye, Keqiang
Publicado 2017

UNC5C Receptor Proteolytic Cleavage by Active AEP Promotes Dopaminergic Neuronal Degeneration in Parkinson's Disease

por Chen, Guiqin, Ahn, Eun Hee, Kang, Seong Su, Xia, Yiyuan, Liu, Xia, Zhang, Zhaohui, Ye, Keqiang
Publicado 2022

Oral Treatments With the TrkB Ligand Prodrug, R13, Promote Enhanced Axon Regeneration Following Peripheral Nerve Injury

por English, Arthur W., Carrasco, Dario, Hoffman, Dustin, Isaacson, Robin, Kang, Seong Su, Khan, Samia, Liu, Xia, Ye, Keqiang
Publicado 2022

The couple of netrin-1/α-Synuclein regulates the survival of dopaminergic neurons via α-Synuclein disaggregation

por Kang, Eun Ji, Jang, Seung Min, Lee, Ye Ji, Jeong, Ye Ji, Kim, You Jin, Kang, Seong Su, Ahn, Eun Hee
Publicado 2023

C/EBPβ/AEP is age-dependently activated in Parkinson’s disease and mediates α-synuclein in the gut and brain

por Wang, Hualong, Chen, Guiqin, Ahn, Eun Hee, Xia, Yiyuan, Kang, Seong Su, Liu, Xia, Liu, Chang, Han, Ming-Hu, Chen, Shengdi, Ye, Keqiang
Publicado 2023

Netrin-1 receptor UNC5C cleavage by active δ-secretase enhances neurodegeneration, promoting Alzheimer’s disease pathologies

por Chen, Guiqin, Kang, Seong Su, Wang, Zhihao, Ahn, Eun Hee, Xia, Yiyuan, Liu, Xia, Sandoval, Ivette M., Manfredsson, Fredric P., Zhang, Zhaohui, Ye, Keqiang
Publicado 2021

Netrin‐1 and its receptor DCC modulate survival and death of dopamine neurons and Parkinson’s disease features

por Jasmin, Mélissa, Ahn, Eun Hee, Voutilainen, Merja H, Fombonne, Joanna, Guix, Catherine, Viljakainen, Tuulikki, Kang, Seong Su, Yu, Li‐ying, Saarma, Mart, Mehlen, Patrick, Ye, Keqiang
Publicado 2020

GAP-43 closely interacts with BDNF in hippocampal neurons and is associated with Alzheimer's disease progression

por Lee, Ye Ji, Jeong, Ye Ji, Kang, Eun Ji, Kang, Beom Seok, Lee, Song Hee, Kim, You Jin, Kang, Seong Su, Suh, Sang Won, Ahn, Eun Hee
Publicado 2023

FSH and ApoE4 contribute to Alzheimer’s disease-like pathogenesis via C/EBPβ/δ-secretase in female mice

por Xiong, Jing, Kang, Seong Su, Wang, Mengmeng, Wang, Zhihao, Xia, Yiyuan, Liao, Jianming, Liu, Xia, Yu, Shan-Ping, Zhang, Zhaohui, Ryu, Vitaly, Yuen, Tony, Zaidi, Mone, Ye, Keqiang
Publicado 2023

Inhibition of delta-secretase improves cognitive functions in mouse models of Alzheimer's disease

por Zhang, Zhentao, Obianyo, Obiamaka, Dall, Elfriede, Du, Yuhong, Fu, Haian, Liu, Xia, Kang, Seong Su, Song, Mingke, Yu, Shan-Ping, Cabrele, Chiara, Schubert, Mario, Li, Xiaoguang, Wang, Jian-Zhi, Brandstetter, Hans, Ye, Keqiang
Publicado 2017

Discovery of a dual inhibitor of NQO1 and GSTP1 for treating glioblastoma

por Lei, Kecheng, Gu, Xiaoxia, Alvarado, Alvaro G., Du, Yuhong, Luo, Shilin, Ahn, Eun Hee, Kang, Seong Su, Ji, Bing, Liu, Xia, Mao, Hui, Fu, Haian, Kornblum, Harley I., Jin, Lingjing, Li, Hua, Ye, Keqiang
Publicado 2020

Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer’s disease

por Zhang, Zhentao, Song, Mingke, Liu, Xia, Kang, Seong Su, Kwon, Il-Sun, Duong, Duc M., Seyfried, Nicholas T., Hu, William T., Liu, Zhixue, Wang, Jian-zhi, Cheng, Liming, Sun, Yi E., Yu, Shan Ping, Levey, Allan I., Ye, Keqiang
Publicado 2014

Brain atlas for glycoprotein hormone receptors at single-transcript level

por Ryu, Vitaly, Gumerova, Anisa, Korkmaz, Funda, Kang, Seong Su, Katsel, Pavel, Miyashita, Sari, Kannangara, Hasni, Cullen, Liam, Chan, Pokman, Kuo, TanChun, Padilla, Ashley, Sultana, Farhath, Wizman, Soleil A, Kramskiy, Natan, Zaidi, Samir, Kim, Se-Min, New, Maria I, Rosen, Clifford J, Goosens, Ki A, Frolinger, Tal, Haroutunian, Vahram, Ye, Keqiang, Lizneva, Daria, Davies, Terry F, Yuen, Tony, Zaidi, Mone
Publicado 2022