Structural Insight Into the SARS-CoV-2 Nucleocapsid Protein C-Terminal Domain Reveals a Novel Recognition Mechanism for Viral Transcriptional Regulatory Sequences

por Yang, Mei, He, Suhua, Chen, Xiaoxue, Huang, Zhaoxia, Zhou, Ziliang, Zhou, Zhechong, Chen, Qiuyue, Chen, Shoudeng, Kang, Sisi
Publicado 2021

Structural insight reveals SARS-CoV-2 ORF7a as an immunomodulating factor for human CD14(+) monocytes

por Zhou, Ziliang, Huang, Chunliu, Zhou, Zhechong, Huang, Zhaoxia, Su, Lili, Kang, Sisi, Chen, Xiaoxue, Chen, Qiuyue, He, Suhua, Rong, Xia, Xiao, Fei, Chen, Jun, Chen, Shoudeng
Publicado 2021

Crystal structure of SARS-CoV-2 nucleocapsid protein RNA binding domain reveals potential unique drug targeting sites

por Kang, Sisi, Yang, Mei, Hong, Zhongsi, Zhang, Liping, Huang, Zhaoxia, Chen, Xiaoxue, He, Suhua, Zhou, Ziliang, Zhou, Zhechong, Chen, Qiuyue, Yan, Yan, Zhang, Changsheng, Shan, Hong, Chen, Shoudeng
Publicado 2020

Crystal Structures of Bat and Human Coronavirus ORF8 Protein Ig-Like Domain Provide Insights Into the Diversity of Immune Responses

por Chen, Xiaoxue, Zhou, Zhechong, Huang, Chunliu, Zhou, Ziliang, Kang, Sisi, Huang, Zhaoxia, Jiang, Guanmin, Hong, Zhongsi, Chen, Qiuyue, Yang, Mei, He, Suhua, Liu, Siqi, Chen, Jie, Li, Kenan, Li, Xin, Liao, Jing, Chen, Jun, Chen, Shoudeng
Publicado 2021

Structural insights of human mitofusin-2 into mitochondrial fusion and CMT2A onset

por Li, Yu-Jie, Cao, Yu-Lu, Feng, Jian-Xiong, Qi, Yuanbo, Meng, Shuxia, Yang, Jie-Feng, Zhong, Ya-Ting, Kang, Sisi, Chen, Xiaoxue, Lan, Lan, Luo, Li, Yu, Bing, Chen, Shoudeng, Chan, David C., Hu, Junjie, Gao, Song
Publicado 2019

A SARS-CoV-2 antibody curbs viral nucleocapsid protein-induced complement hyperactivation

por Kang, Sisi, Yang, Mei, He, Suhua, Wang, Yueming, Chen, Xiaoxue, Chen, Yao-Qing, Hong, Zhongsi, Liu, Jing, Jiang, Guanmin, Chen, Qiuyue, Zhou, Ziliang, Zhou, Zhechong, Huang, Zhaoxia, Huang, Xi, He, Huanhuan, Zheng, Weihong, Liao, Hua-Xin, Xiao, Fei, Shan, Hong, Chen, Shoudeng
Publicado 2021

Structural Basis of a Human Neutralizing Antibody Specific to the SARS-CoV-2 Spike Protein Receptor-Binding Domain

por Yang, Mei, Li, Jiaqi, Huang, Zhaoxia, Li, Heng, Wang, Yueming, Wang, Xiaoli, Kang, Sisi, Huang, Xing, Wu, Changwen, Liu, Tong, Jia, Zhenxing, Liang, Junlang, Yuan, Xiaohui, He, Suhua, Chen, Xiaoxue, Zhou, Zhechong, Chen, Qiuyue, Liu, Siqi, Li, Jing, Zheng, Huiwen, Liu, Xi, Li, Kenan, Yao, Xiaojun, Lang, Bin, Liu, Longding, Liao, Hua-Xin, Chen, Shoudeng
Publicado 2021

Highly pathogenic coronavirus N protein aggravates inflammation by MASP-2-mediated lectin complement pathway overactivation

por Gao, Ting, Zhu, Lin, Liu, Hainan, Zhang, Xiaopeng, Wang, Tingting, Fu, Yangbo, Li, Hongzhen, Dong, Qincai, Hu, Yong, Zhang, Zhang, Jin, Jing, Liu, Zijing, Yang, Weihong, Liu, Yaoning, Jin, Yanwen, Li, Kaitong, Xiao, Yongjiu, Liu, Junli, Zhao, Huailong, Liu, Yue, Li, Ping, Song, Jibo, Zhang, Lu, Gao, Yuwei, Kang, Sisi, Chen, Shoudeng, Ma, Qingjun, Bian, Xiuwu, Chen, Wei, Liu, Xuan, Mao, Qing, Cao, Cheng
Publicado 2022